Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Duncan W. Wilson"'
Autor:
Duncan W. Wilson
Publikováno v:
Viruses, Vol 13, Iss 8, p 1622 (2021)
The alphaherpesviruses are pathogens of the mammalian nervous system. Initial infection is commonly at mucosal epithelia, followed by spread to, and establishment of latency in, the peripheral nervous system. During productive infection, viral gene e
Externí odkaz:
https://doaj.org/article/b5b8a8a1b93341ecbc4b8ef797ab40da
Autor:
Derek Walsh, Jeffrey N. Savas, Ewa Bomba-Warczak, Himanshu Kharkwal, Sofia V. Zaichick, Vladimir Jovasevic, DongHo Kim, Gregory A. Smith, Duncan W. Wilson, Patricia J. Sollars, Gary E. Pickard, Caitlin E. Pegg
Publikováno v:
Nature. 599:662-666
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established1. Recurrent infections arise sporadically from the peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a876cab33ba4e2d167899e3ff73eab7
https://doi.org/10.1038/s41586-021-04106-w
https://doi.org/10.1038/s41586-021-04106-w
Publikováno v:
J Virol
The assembly and egress of alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), within neurons is poorly understood. A key unresolved question is the structure of the viral particle that moves by anterograde tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d957174266a9f85e77fe573c4e24ed25
https://doi.org/10.1128/jvi.02178-21
https://doi.org/10.1128/jvi.02178-21
Autor:
Caitlin E, Pegg, Sofia V, Zaichick, Ewa, Bomba-Warczak, Vladimir, Jovasevic, DongHo, Kim, Himanshu, Kharkwal, Duncan W, Wilson, Derek, Walsh, Patricia J, Sollars, Gary E, Pickard, Jeffrey N, Savas, Gregory A, Smith
Publikováno v:
Nature. 599(7886)
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4895b3087537a3bff0b81fd50cfe96b9
https://pubmed.ncbi.nlm.nih.gov/34811520
https://pubmed.ncbi.nlm.nih.gov/34811520
Autor:
Imran Nazir Ahmad, Duncan W. Wilson
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 5969, p 5969 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 5969, p 5969 (2020)
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA replication, capsid assembly, and genome packaging take place in the infected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785d9b350d795609c00df379ff760ce8
http://europepmc.org/articles/PMC7503644
http://europepmc.org/articles/PMC7503644
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008597 (2020)
PLoS Pathogens
PLoS Pathogens
During infection of neurons by alphaherpesviruses including Pseudorabies virus (PRV) and Herpes simplex virus type 1 (HSV-1) viral nucleocapsids assemble in the cell nucleus, become enveloped in the cell body then traffic into and down axons to nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd0a65d1520fefc98e2c78bf40137dc
https://doaj.org/article/fccfc18945144d52943a48fe94b8ae36
https://doaj.org/article/fccfc18945144d52943a48fe94b8ae36
Autor:
Duncan W. Wilson, Jenna Barnes
Publikováno v:
J Virol
Capsid envelopment during assembly of the neurotropic herpesviruses herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV) in the infected cell cytoplasm is thought to involve the late-acting cellular ESCRT (endosomal sorting complex required fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360a1bac5f793b655c6d6e6da45d49bd
https://doi.org/10.1128/jvi.01641-19
https://doi.org/10.1128/jvi.01641-19
Autor:
Jenna Barnes, Duncan W. Wilson
Publikováno v:
Journal of Virology. 93
The Herpesviridae are structurally complex DNA viruses whose capsids undergo primary envelopment at the inner nuclear membrane and secondary envelopment at organelles in the cytoplasm. In both locations, there is evidence that envelope formation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a726e282ec481cb3cc97d9a92fbe6648
https://doi.org/10.1128/jvi.00392-19
https://doi.org/10.1128/jvi.00392-19
Publikováno v:
Journal of Virology. 90:7257-7267
UL36p (VP1/2) is the largest protein encoded by herpes simplex virus 1 (HSV-1) and resides in the innermost layer of tegument, the complex protein layer between the capsid and envelope. UL36p performs multiple functions in the HSV life cycle, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59367fada2fb4e0ef668f19bd6957b6
https://doi.org/10.1128/jvi.00857-16
https://doi.org/10.1128/jvi.00857-16
Autor:
Duncan W. Wilson, Drishya Diwaker
Publikováno v:
Viruses
The Alphaherpesvirinae include the neurotropic pathogens herpes simplex virus and varicella zoster virus of humans and pseudorabies virus of swine. These viruses establish lifelong latency in the nuclei of peripheral ganglia, but utilize the peripher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3884eff8b4bb8a6724a4173e3d28f151
https://doi.org/10.3390/v11121165
https://doi.org/10.3390/v11121165