Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Duncan W, Wilson"'
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008597 (2020)
During infection of neurons by alphaherpesviruses including Pseudorabies virus (PRV) and Herpes simplex virus type 1 (HSV-1) viral nucleocapsids assemble in the cell nucleus, become enveloped in the cell body then traffic into and down axons to nerve
Externí odkaz:
https://doaj.org/article/fccfc18945144d52943a48fe94b8ae36
Autor:
Duncan W. Wilson
Publikováno v:
Viruses, Vol 13, Iss 8, p 1622 (2021)
The alphaherpesviruses are pathogens of the mammalian nervous system. Initial infection is commonly at mucosal epithelia, followed by spread to, and establishment of latency in, the peripheral nervous system. During productive infection, viral gene e
Externí odkaz:
https://doaj.org/article/b5b8a8a1b93341ecbc4b8ef797ab40da
Autor:
Derek Walsh, Jeffrey N. Savas, Ewa Bomba-Warczak, Himanshu Kharkwal, Sofia V. Zaichick, Vladimir Jovasevic, DongHo Kim, Gregory A. Smith, Duncan W. Wilson, Patricia J. Sollars, Gary E. Pickard, Caitlin E. Pegg
Publikováno v:
Nature. 599:662-666
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established1. Recurrent infections arise sporadically from the peripheral
Autor:
Imran Ahmad, Duncan W. Wilson
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 5969 (2020)
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA replication, capsid assembly, and genome packaging take place in the infected
Externí odkaz:
https://doaj.org/article/31edaf4a101f4134847b3e83c7a525d1
Publikováno v:
J Virol
The assembly and egress of alphaherpesviruses, including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), within neurons is poorly understood. A key unresolved question is the structure of the viral particle that moves by anterograde tran
Autor:
Caitlin E, Pegg, Sofia V, Zaichick, Ewa, Bomba-Warczak, Vladimir, Jovasevic, DongHo, Kim, Himanshu, Kharkwal, Duncan W, Wilson, Derek, Walsh, Patricia J, Sollars, Gary E, Pickard, Jeffrey N, Savas, Gregory A, Smith
Publikováno v:
Nature. 599(7886)
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008597 (2020)
PLoS Pathogens
PLoS Pathogens
During infection of neurons by alphaherpesviruses including Pseudorabies virus (PRV) and Herpes simplex virus type 1 (HSV-1) viral nucleocapsids assemble in the cell nucleus, become enveloped in the cell body then traffic into and down axons to nerve
Autor:
Duncan W. Wilson, Jenna Barnes
Publikováno v:
J Virol
Capsid envelopment during assembly of the neurotropic herpesviruses herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV) in the infected cell cytoplasm is thought to involve the late-acting cellular ESCRT (endosomal sorting complex required fo
Autor:
Jenna Barnes, Duncan W. Wilson
Publikováno v:
Journal of Virology. 93
The Herpesviridae are structurally complex DNA viruses whose capsids undergo primary envelopment at the inner nuclear membrane and secondary envelopment at organelles in the cytoplasm. In both locations, there is evidence that envelope formation and
Publikováno v:
Journal of Virology. 90:7257-7267
UL36p (VP1/2) is the largest protein encoded by herpes simplex virus 1 (HSV-1) and resides in the innermost layer of tegument, the complex protein layer between the capsid and envelope. UL36p performs multiple functions in the HSV life cycle, includi