Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Duncan R. Hewett"'
Autor:
Natasha L. Friend, Duncan R. Hewett, Vasilios Panagopoulos, Jacqueline E. Noll, Kate Vandyke, Krzysztof M. Mrozik, Stephen Fitter, Andrew C.W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 9, Pp 554-572 (2020)
Abstract The protein SAMSN1 was recently identified as a putative tumor suppressor in multiple myeloma, with re‐expression of Samsn1 in the 5TGM1/KaLwRij murine model of myeloma leading to a near complete abrogation of intramedullary tumor growth.
Externí odkaz:
https://doaj.org/article/156a98f254f24fe5bd74506dfb885296
Autor:
Krzysztof M. Mrozik, Chee M. Cheong, Duncan R. Hewett, Jacqueline E. Noll, Khatora S. Opperman, Alaknanda Adwal, Darryl L. Russell, Orest W. Blaschuk, Kate Vandyke, Andrew C. W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 6, Pp 339-353 (2020)
Abstract N‐cadherin is a homophilic cell‐cell adhesion molecule that plays a critical role in maintaining vascular stability and modulating endothelial barrier permeability. Pre‐clinical studies have shown that the N‐cadherin antagonist pepti
Externí odkaz:
https://doaj.org/article/c6826197d1b54a479b78471d9ab82b5d
Autor:
Mara N. Zeissig, Duncan R. Hewett, Vasilios Panagopoulos, Krzysztof M. Mrozik, L. Bik To, Peter I. Croucher, Andrew C.W. Zannettino, Kate Vandyke
Publikováno v:
Haematologica, Vol 106, Iss 12 (2020)
Multiple myeloma (MM) disease progression is dependent on the ability of MM plasma cells (PC) to egress from the bone marrow (BM), enter the circulation and disseminate to distal BM sites. Expression of the chemokine CXCL12 by BM stromal cells is cru
Externí odkaz:
https://doaj.org/article/6d1b9b271dcc4ee990634f98c7077a89
Autor:
Duncan R. Hewett, Kate Vandyke, David M. Lawrence, Natasha Friend, Jacqueline E. Noll, Joel M. Geoghegan, Peter I. Croucher, Andrew C.W. Zannettino
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 972-981 (2017)
Multiple myeloma (MM) is a hematological malignancy resulting from the uncontrolled proliferation of antibody-producing plasma cells in the bone marrow. At diagnosis, independent plasma cell tumors are found throughout the skeleton. The recirculation
Externí odkaz:
https://doaj.org/article/9891e1730b4e4a3a92cc6a87bb1595a4
Autor:
Jacqueline E. Noll, Duncan R. Hewett, Sharon A. Williams, Kate Vandyke, Chung Kok, Luen B. To, Andrew C.W. Zannettino
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 572-585 (2014)
Multiple myeloma (MM), a hematological malignancy characterized by the clonal growth of malignant plasma cells (PCs) in the bone marrow, is preceded by the benign asymptomatic condition, monoclonal gammopathy of undetermined significance (MGUS). Seve
Externí odkaz:
https://doaj.org/article/d9be91c1837a4d4c8250daf7aca31327
Autor:
Natasha Friend, Jacqueline E Noll, Khatora S Opperman, Kimberley C Clark, Krzysztof M Mrozik, Kate Vandyke, Duncan R Hewett, Andrew C W Zannettino
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228408 (2020)
Multiple myeloma, a plasma cell malignancy, is a genetically heterogeneous disease and the genetic factors that contribute to its development and progression remain to be fully elucidated. The tumour suppressor gene GLIPR1 has previously been shown t
Externí odkaz:
https://doaj.org/article/7cb27827dcad42d981a5755b63258ea0
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Disease progression and relapse in multiple myeloma is dependent on the ability of the multiple myeloma plasma cells (PC) to reenter the circulation and disseminate throughout the bone marrow. Increased bone marrow hypoxia is associated with increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7becda77a17ee4d0f7f53c99a9f7db93
https://doi.org/10.1158/0008-5472.c.6509067.v1
https://doi.org/10.1158/0008-5472.c.6509067.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Table of genes dysregulated with overexpression of HIF-2alpha in LP-1 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1748287a0abc55f9f56d92b93286e3c9
https://doi.org/10.1158/0008-5472.22414728.v1
https://doi.org/10.1158/0008-5472.22414728.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Supplementary Figure Legends and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e9da169194aece84a84b17d52ede9d
https://doi.org/10.1158/0008-5472.22414731.v1
https://doi.org/10.1158/0008-5472.22414731.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Supp. Figure 3. CCR1 expression is upregulated by hypoxia in human MM cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab4117931f9b2b3437db2c911888946
https://doi.org/10.1158/0008-5472.22414740
https://doi.org/10.1158/0008-5472.22414740