Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Duncan M. Short"'
Autor:
Janet M. Paterson, Thomas H. Gillingwater, Michael A. Cousin, Sara Meredith, Kevin A. Robertson, Mayank B. Dutia, Calum Sutherland, Thomas M. Wishart, Duncan M. Short
Publikováno v:
Molecular & Cellular Proteomics. 6:1318-1330
Non-somatic synaptic and axonal compartments of neurons are primary pathological targets in many neurodegenerative conditions, ranging from Alzheimer disease through to motor neuron disease. Axons and synapses are protected from degeneration by the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305325958eca68006ee711c55973262d
https://doi.org/10.1074/mcp.m600457-mcp200
https://doi.org/10.1074/mcp.m600457-mcp200
Autor:
Duncan M. Short, David G. Watson, Elizabeth M. Ellis, Oleg A. Barski, Gail McGarvie, Robert C. Lyon
Publikováno v:
Toxicology and Applied Pharmacology. 210:163-170
The reductive metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, was studied in mouse liver. Using an HPLC-based stopped assay, the primary reduced metabolite was identified as 6-hydroxy-trans, trans-2,4-hexadienal (OH/CHO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41918cddad6ffb1d6757480218f76e9b
https://doi.org/10.1016/j.taap.2005.09.017
https://doi.org/10.1016/j.taap.2005.09.017
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 3:246-252
Saccharomyces cerevisiae flavocytochrome b 2 couples the oxidation of L-lactate to the reduction of cytochrome c. The second-order rate constant for cytochrome c reduction by flavocytochrome b 2 depends on the rate of complex formation and is sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0367a3f61910ae3ade9cc0a0b6756d1
https://doi.org/10.1007/pl00010651
https://doi.org/10.1007/pl00010651
Autor:
Forbes D C Manson, C Bell, P White, Simon Daff, Sharp Re, Duncan M. Short, S K Chapman, G A Reid
Publikováno v:
Biochemistry. 35:6351-6357
Flavocytochrome b2 from Saccharomyces cerevisiae couples L-lactate dehydrogenation to cytochrome c reduction. At 25 degrees C, 0.10 M ionic strength, and saturating L-lactate concentration, the turnover rate is 207 s-1 [per cytochrome c reduced; Mile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8a8f108be64b54d3e0461da30e5c8d
https://doi.org/10.1021/bi9522561
https://doi.org/10.1021/bi9522561
Autor:
Michael Allerhand, Lorraine E. Kerr, Ruth F. Deighton, Ian R. Whittle, Duncan M. Short, James McCulloch
Publikováno v:
Proteomics. 10(6)
Thirteen proteins (identified with 2-D gels and MALDI-TOF MS) are significantly altered during staurosporine-induced apoptosis in SH-SY5Y cells. To gain further insight into the integrated cellular response to apoptosis, we have investigated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313e5e2368bc9a6541535e42251eea57
https://pubmed.ncbi.nlm.nih.gov/20377384
https://pubmed.ncbi.nlm.nih.gov/20377384
Autor:
James McCulloch, Alan J. Gow, Ruth F. Deighton, Duncan M. Short, Ian R. Whittle, Richard J. McGregor
Publikováno v:
Journal of neuroscience methods. 180(2)
Proteomic studies offer enormous potential for gaining insight into cellular dynamics and disease processes. An immediate challenge for enhancing the utility of proteomics in translational research lies in methods of handling and interpreting the lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3911fc86e20e3adb36696ccbdadfaa
https://pubmed.ncbi.nlm.nih.gov/19464520
https://pubmed.ncbi.nlm.nih.gov/19464520
Autor:
Colin Smith, Lorraine E. Kerr, Ian R. Whittle, Ruth F. Deighton, Duncan M. Short, James McCulloch
Publikováno v:
British journal of neurosurgery. 21(6)
Primary malignant brain tumours (anaplastic glioma and glioblastoma) display heterogenous histopathology and diverse genetic abnormalities. These tumours remain incurable with no significant improvement in median survival times in the last 20 years,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad46e24ad77d503c767abf53dbba64e7
https://pubmed.ncbi.nlm.nih.gov/18071984
https://pubmed.ncbi.nlm.nih.gov/18071984
Autor:
James McCulloch, John Sharkey, Lorraine E. Kerr, Ian D. Heron, Jui-Lee A. Birse-Archbold, Duncan M. Short
Publikováno v:
Proteomics. 7(17)
Apoptosis contributes to cell death after cerebral ischaemia. A quantitative proteomics approach has been employed to define alterations in protein levels in apoptosis induced with staurosporine (STS). Human neuroblastoma derived SH-SY5Y cells were t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cead5e0a5ea19937e90d314ed8580d56
https://pubmed.ncbi.nlm.nih.gov/17676660
https://pubmed.ncbi.nlm.nih.gov/17676660
Autor:
J Sharkey, Ailsa L. McGregor, Jui-Lee A. Birse-Archbold, Duncan M. Short, John S. Kelly, Lorraine E. Kerr, G Carlson, James McCulloch, I. Heron, Jane Thompson, D. C. Macdonald
Publikováno v:
Oncogene. 26(18)
The proapoptotic B-cell lymphoma-2 family protein Bax is a key regulatory point in the intrinsic apoptotic pathway. However, the factors controlling the process of Bax activation and translocation to mitochondria have yet to be fully identified and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a06ed41efc18b912668bdde54e711f
https://pubmed.ncbi.nlm.nih.gov/17072349
https://pubmed.ncbi.nlm.nih.gov/17072349
Publikováno v:
Biochemical Society transactions. 24(1)
Introduction Most of the recent intense scientific effort towards providing an understanding of electron transfer in proteins has focused on intraprotein electron transfer and on the pathway between the donor (D) and acceptor (A) redox centres. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04e26485dc2ed1b0092b48de7376b9c
https://pubmed.ncbi.nlm.nih.gov/8674751
https://pubmed.ncbi.nlm.nih.gov/8674751