Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Duncan Hieu M. Dam"'
Publikováno v:
Materials Chemistry Frontiers. 3:1113-1122
Intervention for non-melanoma skin cancer (NMSC) remains largely surgical, and development of an effective, tissue-salvaging, less invasive therapy is a significant unmet need. Photodynamic therapy is a non-invasive approach for NMSC, but depends on
Autor:
Jeong Min Yu, Sophia A. Jelsma, Haoming Liu, Betty Y. Kong, Duncan Hieu M. Dam, Amy S. Paller
Publikováno v:
J Invest Dermatol
IGF-1 receptor (IGF1R) signaling promotes keratinocyte proliferation, migration, and survival. However, the mechanism of IGF1R endocytosis in normal keratinocytes remains unclear. Confocal, super resolution structured illumination microscopy, total i
Autor:
Duncan Hieu M. Dam, Amy S. Paller
An organized series of complicated biological and molecular phenomena is required for normal skin wound healing. These processes depend on normal cellular responses to cytokines, growth factors, and other mediators, such as clotting factors, prostagl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd34923daa49338626e16f9fcffdef3
https://doi.org/10.1016/bs.pmbts.2017.12.006
https://doi.org/10.1016/bs.pmbts.2017.12.006
Publikováno v:
Wound Healing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d611f976a172e2c111e9e21e78e408
https://doi.org/10.1002/9781119282518.ch13
https://doi.org/10.1002/9781119282518.ch13
Publikováno v:
ACS Nano. 9:9859-9867
This paper describes how gold nanoparticle nanoconstructs can enhance anti-cancer effects of lysosomal targeting aptamers in breast cancer cells. Nanoconstructs consisting of anti-HER2 aptamer (human epidermal growth factor receptor 2, HApt) densely
Publikováno v:
Nano Letters
This paper describes how in vitro efficacy of aptamer-loaded gold nanostars (Apt-AuNS) can be enhanced by the increased loading of a G-quadruplex homodimer AS1411 (Apt) on the AuNS surface. In a low pH buffer environment, the loading density of Apt o
Publikováno v:
Molecular Pharmaceutics
We report the design of a nanoconstruct that can function as a cell-type independent agent by targeting the ubiquitous protein nucleolin. Gold nanostars (AuNS) loaded with high densities of nucleolin-specific DNA aptamer AS1411 (Apt-AuNS) produced an
Publikováno v:
Therapeutic Delivery. 3:1263-1267
Nuclear-targeted therapy has received increasing attention as a potential strategy to improve the therapeutic efficacy of treating cancer. The main challenges include targeting, drug-delivery efficiency and release of anticancer agents to the cancer
Autor:
Xiao Qi Wang, Luke Miller, Duncan Hieu M. Dam, Amy S. Paller, Mahima Vijay, Sarah L. Sheu, Desmond Shipp
Activation of insulin-like growth factor-1 (IGF-1) receptor (IGF1R) signaling induces keratinocyte migration, but little is known about its regulation, including in diabetic wounds. GM3, a lipid raft ganglioside synthesized by GM3 synthase (GM3S), re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32b3a7bf149db5c3644eeefcd34f97f
https://europepmc.org/articles/PMC5499673/
https://europepmc.org/articles/PMC5499673/
Publikováno v:
The journal of physical chemistry letters. 6(24)
This Letter reports the shape-dependent third-order nonlinear optical properties of anisotropic gold nanoparticles. We characterized the nonlinear absorption coefficients of nanorods, nanostars, and nanoshells using femtosecond Z-scan measurements. B