Výsledky vyhledávání - "Duncan Casson"

Combined OX40L and mTOR blockade controls effector T cell activation while preserving T reg reconstitution after transplant

Autor: Kayla Betz, Katie Zeleski, Jeffrey S. Miller, Victor Tkachev, Ian Kirby, Melanie Brown, Benjamin Watkins, Leslie S. Kean, Duncan Casson, Phil Bland-Ward, Sarah Cooley, Daniel J. Hunt, John B. Schell, Bruce R. Blazar, Scott N. Furlan, Alison Yu, Angela Panoskaltsis-Mortari, Hengqi Betty Zheng

Publikováno v: Science Translational Medicine. 9

A critical question facing the field of transplantation is how to control effector T cell (Teff) activation while preserving regulatory T cell (Treg) function. Standard calcineurin inhibitor-based strategies can partially control Teffs, but breakthro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fc4a5b788f9c32951cecc249a43daf3
https://doi.org/10.1126/scitranslmed.aan3085

Zobrazit plný text záznamu

A Novel Therapeutic Strategy to Control Conventional T-Cells While Supporting Treg Reconstitution Post-Transplant: Long-Term GVHD-Free Survival by Combining OX40L Blockade with Rapamycin

Autor: Duncan Casson, Kayla Betz, Daniel J. Hunt, Katie Zeleski, Melanie Brown, Hengqi Zheng, Benjamin Watkins, Alison Yu, Leslie S. Kean, Angela Panoskaltsis-Mortari, Phil Bland-Ward, Victor Tkachev, Ian Kirby, Scott N. Furlan, Bruce R. Blazar

Publikováno v: Biology of Blood and Marrow Transplantation. 23:S20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eeed62d2342db708ed796ad0e9b94cee
https://doi.org/10.1016/j.bbmt.2016.12.004

Zobrazit plný text záznamu

Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin

Autor: Daniel J. Hunt, Duncan Casson, Kayla Betz, Ian Kirby, Katie Zeleski, Melanie Brown, Phil Bland-Ward, Alison Yu, Angela Panoskaltsis-Mortari, Ben Watkins, Scott N. Furlan, Betty Zheng, Bruce R. Blazar, Leslie S. Kean, Victor Tkachev

Publikováno v: Blood. 128:3341-3341

While calcineurin inhibition (CNI)-based strategies remain the mainstay for GVHD prevention, CNI are notoriously antagonistic to immune tolerance induction. Rapamycin (Rapa) has been shown to be more pro-tolerogenic; however, the best agents to combi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c992827f157f5dbbb5615b67f3136431
https://doi.org/10.1182/blood.v128.22.3341.3341

Zobrazit plný text záznamu

The biotransformation of t -butylacetonitrile and its boron-containing analogue trimethylamine-cyanoborane by Brevibacterium R312

Autor: Christopher J. Knowles, Anthony J. Millais, John A Lovelady, Andrea M. Nicholson, Duncan Casson

Publikováno v: Archives of Microbiology. 168:164-168

The ability of the nitrile hydratase/amidase system from Brevibacterium R312 to biotransform tert-butylacetonitrile was studied with a view to their utilisation in the production of novel amino acids from isostructural compounds. Brevibacterium R312

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d34da6decf15482ef84eea8b77cc481
https://doi.org/10.1007/s002030050483

Zobrazit plný text záznamu

Impact of EC regulations on a UK biotechnology company

Autor: Duncan Casson

Publikováno v: Journal of Chemical Technology AND Biotechnology. 64:305-307

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ade19f4153a54a59f6ae75d6e26ef71
https://doi.org/10.1002/jctb.280640318

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání