Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Duncan Bassett"'
Autor:
Jonathan H. Tobias, Emma L. Duncan, Erika Kague, Chrissy L. Hammond, Celia L. Gregson, Duncan Bassett, Graham R. Williams, Josine L. Min, Tom R. Gaunt, David Karasik, Claes Ohlsson, Fernando Rivadeneira, James R. Edwards, Fadil M. Hannan, John P. Kemp, Sophie J. Gilbert, Nerea Alonso, Neelam Hassan, Juliet E. Compston, Stuart H. Ralston
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
The discovery that sclerostin is the defective protein underlying the rare heritable bone mass disorder, sclerosteosis, ultimately led to development of anti-sclerostin antibodies as a new treatment for osteoporosis. In the era of large scale GWAS, m
Externí odkaz:
https://doaj.org/article/213a3053bba14147b16d8929aed76dac
Autor:
Natalie Butterfield, Naila Mannan, Katherine Curry, Elizabeth McAninch, Antonio Bianco, Graham Williams, Duncan Bassett
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100634- (2020)
Externí odkaz:
https://doaj.org/article/51109b36e34e4d38a10fafa2d8210bc8
Autor:
Gregson, Celia L., Newell, Felicity, Leo, Paul J., Clark, Graeme R., Paternoster, Lavinia, Marshall, Mhairi, Forgetta, Vincenzo, Morris, John A., Ge, Bing, Bao, Xiao, Duncan Bassett, J.H., Williams, Graham R., Youlten, Scott E., Croucher, Peter I., Davey Smith, George, Evans, David M., Kemp, John P., Brown, Matthew A., Tobias, Jon H., Duncan, Emma L.
Publikováno v:
In Bone September 2018 114:62-71
Autor:
Anna L Swan, Christine Schütt, Jan Rozman, Maria Del Mar Muñiz Moreno, Stefan Brandmaier, Michelle Simon, Stefanie Leuchtenberger, Mark Griffiths, Robert Brommage, Piia Keskivali-Bond, Harald Grallert, Thomas Werner, Raffaele Teperino, Lore Becker, Gregor Miller, Ala Moshiri, John R Seavitt, Derek D Cissell, Terrence F Meehan, Elif F Acar, Christopher J Lelliott, Ann M Flenniken, Marie-France Champy, Tania Sorg, Abdel Ayadi, Robert E Braun, Heather Cater, Mary E Dickinson, Paul Flicek, Juan Gallegos, Elena J Ghirardello, Jason D Heaney, Sylvie Jacquot, Connor Lally, John G Logan, Lydia Teboul, Jeremy Mason, Nadine Spielmann, Colin McKerlie, Stephen A Murray, Lauryl M J Nutter, Kristian F Odfalk, Helen Parkinson, Jan Prochazka, Corey L Reynolds, Mohammed Selloum, Frantisek Spoutil, Karen L Svenson, Taylor S Vales, Sara E Wells, Jacqueline K White, Radislav Sedlacek, Wolfgang Wurst, K C Kent Lloyd, Peter I Croucher, Helmut Fuchs, Graham R Williams, J H Duncan Bassett, Valerie Gailus-Durner, Yann Herault, Ann-Marie Mallon, Steve D M Brown, Philipp Mayer-Kuckuk, Martin Hrabe de Angelis, IMPC Consortium
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009190 (2020)
The genetic landscape of diseases associated with changes in bone mineral density (BMD), such as osteoporosis, is only partially understood. Here, we explored data from 3,823 mutant mouse strains for BMD, a measure that is frequently altered in a ran
Externí odkaz:
https://doaj.org/article/14895730ccd5432c954b9d406684a8d3
Autor:
Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras
Publikováno v:
eLife, Vol 9 (2020)
Functional characterisation of cell-type-specific regulatory networks is key to establish a causal link between genetic variation and phenotype. The osteoclast offers a unique model for interrogating the contribution of co-regulated genes to in vivo
Externí odkaz:
https://doaj.org/article/3598a6a41082456e82266d54eb35c4ad
Autor:
Kourosh Ahmadzadeh, Marie Pereira, Margot Vanoppen, Eline Bernaerts, Jeong‐Hun Ko, Tania Mitera, Christy Maksoudian, Bella B Manshian, Stefaan Soenen, Carlos D Rose, Graham R Williams, J H Duncan Bassett, Patrick Matthys, Carine Wouters, Jacques Behmoaras
Publikováno v:
EMBO Rep
Macrophages undergo plasma membrane fusion and cell multinucleation to form multinucleated giant cells (MGCs) such as osteoclasts in bone, Langhans giant cells (LGCs) as part of granulomas or foreign-body giant cells (FBGCs) in reaction to exogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bbea4f523b4670ab9d0e6c9b5031dc
https://europepmc.org/articles/PMC10074087/
https://europepmc.org/articles/PMC10074087/
Autor:
null Kreepa G. Kooblall, null Mark Stevenson, null Michelle Stewart, null Lachlan Harris, null Oressia Zalucki, null Hannah Dewhurst, null Natalie Butterfield, null Houfu Leng, null Tertius A. Hough, null Da Ma, null Bernard Siow, null Paul Potter, null Roger D. Cox, null Stephen D.M. Brown, null Nicole Horwood, null Benjamin Wright, null Helen Lockstone, null David Buck, null Tonia L. Vincent, null Fadil M. Hannan, null J.H. Duncan Bassett, null Graham R. Williams, null Kate E. Lines, null Michael Piper, null Sara Wells, null Lydia Teboul, null Raoul C. Hennekam, null Rajesh V. Thakker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc95ca703920ea3db5407b11d4acf4a
https://doi.org/10.1002/jbm4.10739/v3/response1
https://doi.org/10.1002/jbm4.10739/v3/response1
Autor:
Kreepa G. Kooblall, Mark Stevenson, Michelle Stewart, Lachlan Harris, Oressia Zalucki, Hannah Dewhurst, Natalie Butterfield, Houfu Leng, Tertius A. Hough, Da Ma, Bernard Siow, Paul Potter, Roger D. Cox, Stephen D.M. Brown, Nicole Horwood, Benjamin Wright, Helen Lockstone, David Buck, Tonia L. Vincent, Fadil M. Hannan, J.H. Duncan Bassett, Graham R. Williams, Kate E. Lines, Michael Piper, Sara Wells, Lydia Teboul, Raoul C. Hennekam, Rajesh V. Thakker
Publikováno v:
JBMR Plus. Wiley-Blackwell Publishing Ltd
The nuclear factor I/X (NFIX) gene encodes a ubiquitously expressed transcription factor whose mutations lead to two allelic disorders characterized by developmental, skeletal, and neural abnormalities, namely, Malan syndrome (MAL) and Marshall–Smi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733e05fc692ac539a58842e462a2270c
Autor:
Carmen Ruggiero, Nelly Durand, Marielle Jarjat, Jacques Barhanin, Elena J. Ghirardello, Michael R.G. Dack, Graham R. Williams, J.H. Duncan Bassett, Enzo Lalli
Publikováno v:
Clinical and Translational Discovery. 2
Background ECRG4/C2ORF40 is a tumour suppressor gene downregulated in several cancer types, which encodes the secreted protein augurin. A wide number of functions in health and disease have been assigned to augurin, but the signalling pathways it reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a015a65bf9cee50bc1088331a6f8ff
https://doi.org/10.1002/ctd2.113
https://doi.org/10.1002/ctd2.113
Autor:
J. Brent Richards, Kaiqiong Zhao, Vincenzo Forgetta, Julyan Keller-Baruch, J. H. Duncan Bassett, Vincent Mooser, Celia M. T. Greenwood, Despoina Manousaki, William D. Leslie
Publikováno v:
Journal of Bone and Mineral Research. 35:1935-1941
Some commonly prescribed drugs are associated with increased risk of osteoporotic fractures. However, fracture risk stratification using skeletal measures is not often performed to identify those at risk before these medications are prescribed. We te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92294d2edba957075bdda8e514d746fd
https://doi.org/10.1002/jbmr.4104
https://doi.org/10.1002/jbmr.4104