Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Duncan B. Judd"'
Autor:
Nick Bailey, Stuart Travers, Richard Storer, Andrew T. Merritt, Duncan B. Judd, Michael C. Hawes, Andrea L. Gore, Anthony W. Dean, Martyn J. Deal, Anthony W.J. Cooper, Stephen P. Watson
Publikováno v:
CHIMIA, Vol 51, Iss 11 (1997)
Solution-phase approaches in combinatorial chemistry complement solid-phase approaches and each can be used to advantage in particular circumstances. Solution-phase synthesis of pools of compounds, whilst allowing successful identification of a selec
Externí odkaz:
https://doaj.org/article/7183308e4fd84a7da26bf2c714528ab2
Autor:
Igor Tokarchuk, Oleksandr Mushii, Alona Dreus, Anastasia A. Koziaruk, Dmyto O. Shapochka, Oleg A. Ryzhak, Serhii O. Venhryk, Iurii S. Golovko, Sergey V. Ryabuhin, Anton I. Hanopolskyi, Duncan B. Judd, Dmitriy M. Volochnyuk
Gastric and colorectal cancer models are essential for the advancement of precision medicine discovery and development. 2D attached monolayer, spheroid and organoid approaches have all been used in the formation of biobanks containing primary patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1347dd3db2f8a9c664a0b877d0f198
https://doi.org/10.1101/2023.02.26.529716
https://doi.org/10.1101/2023.02.26.529716
Publikováno v:
Chemistry – A European Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd14b5abbc3a240056ff1464c238ecb9
https://doi.org/10.1002/chem.202080662
https://doi.org/10.1002/chem.202080662
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(6)
All pharmaceutical products contain organic molecules; the source may be a natural product or a fully synthetic molecule, or a combination of both. Thus, it follows that organic chemistry underpins both existing and upcoming pharmaceutical products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104a008deac7add7a7a3ede9034baa6b
https://pubmed.ncbi.nlm.nih.gov/31429510
https://pubmed.ncbi.nlm.nih.gov/31429510
Autor:
Sergey V. Ryabukhin, Yuliana Zabolotna, Alexander Chuprina, Alexandre Varnek, Yurii S. Moroz, Duncan B. Judd, Olena Savych, Dragos Horvath, Dmitriy M. Volochnyuk
Publikováno v:
Drug Discovery Today Biosilico
Drug Discovery Today Biosilico, Elsevier, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Drug Discovery Today
Drug Discovery Today, Elsevier, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Drug Discovery Today, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Drug Discovery Today Biosilico, Elsevier, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Drug Discovery Today
Drug Discovery Today, Elsevier, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Drug Discovery Today, 2019, 24 (2), pp.390-402. ⟨10.1016/j.drudis.2018.10.016⟩
Over recent years, an industry of compound suppliers has grown to provide drug discovery with screening compounds: it is estimated that there are over 16 million compounds available from these sources. Here, we review the chemical space covered by su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae81d0b6d741b065584d36ab697b64c
https://hal.archives-ouvertes.fr/hal-02347044
https://hal.archives-ouvertes.fr/hal-02347044
Autor:
Laura E. Cross, Kimberley Hughes, Clive A. Smith, Andrew Merritt, Duncan B. Judd, Rebecca Davis
Publikováno v:
Tetrahedron Letters. 50:4906-4911
A powerful direct reductive amination (DRA) method is developed, using catalytic MoO2Cl2 and phenylsilane (PhSiH3) as the reducing agent. The alkylation of a range of amines (pKa 0–7.8) with both an electron-deficient and two electron-rich-aldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e216acd48def3ce0853550861131a13
https://doi.org/10.1016/j.tetlet.2009.06.071
https://doi.org/10.1016/j.tetlet.2009.06.071
Publikováno v:
Organic Letters. 7:843-846
The use of the pentafluorophenyl (PFP) group as a sulfonic acid protecting group has allowed the synthesis of new biaryl- and heterobiaryl-PFP-sulfonate esters by use of the Suzuki-Miyaura reaction. The successful employment of a novel inorganic base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdcd549a22136b61a0645968ca4d522
https://doi.org/10.1021/ol047422o
https://doi.org/10.1021/ol047422o
Autor:
Duncan B. Judd
Publikováno v:
Drug Discovery Today. 18:907-909
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99635f1e8bfceb01a833ca5e9a88278
https://doi.org/10.1016/j.drudis.2013.08.008
https://doi.org/10.1016/j.drudis.2013.08.008
Publikováno v:
QSAR & Combinatorial Science. 23:902-905
A convenient microwave assisted synthesis of sulfonamides from PFP-sulfonates is described. Reaction of various commercially available amines with pentafluorophenyl (PFP) sulfonate esters under microwave irradiation led to the corresponding sulfonami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ceb7f3086be050f6a5da5b0f743e92
https://doi.org/10.1002/qsar.200420038
https://doi.org/10.1002/qsar.200420038
Autor:
Melanie T. Reich, Jonathan D. Wilden, Duncan B. Judd, Stephen Caddick, Daniel Hamza, S. N. Wadman
Publikováno v:
Tetrahedron Letters. 45:2363-2366
Pentafluorophenyl (PFP) acrylate, a stable compact bifunctional scaffold undergoes rapid N-ethylpiperidinium hypophosphite (EPHP) mediated conjugate radical addition to yield a variety of active esters susceptible to further functionalization by amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6abfb2bf60e046e368ba051484eedf
https://doi.org/10.1016/j.tetlet.2004.01.082
https://doi.org/10.1016/j.tetlet.2004.01.082