Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Duncan A. White"'
Publikováno v:
Infection Control & Hospital Epidemiology. 38:1204-1208
OBJECTIVETo evaluate the effectiveness of a computerized clinical decision support intervention aimed at reducing inappropriate Clostridium difficile testingDESIGNRetrospective cohort studySETTINGUniversity of Pennsylvania Health System, comprised of
Highly Non-linear Microfluidic Resistor Elements for Flow Rate-dependent Addressing of Microchannels
Publikováno v:
International Journal of Nonlinear Sciences and Numerical Simulation. 13:319-323
We have developed a microfluidic resistor element exhibiting a hydrodynamic resistance that is strongly dependent on the pressure at the inlet of the device. Such an element can be used to construct microfluidic circuits that possess a highly non-lin
Autor:
Christopher M. Dobson, Tuomas P. J. Knowles, Duncan A. White, Anne Dhulesia, Mark E. Welland, Alexander K. Buell
Publikováno v:
Angewandte Chemie. 124:5339-5344
Autor:
Adam R. Abate, Samuel I. A. Cohen, Duncan A. White, Christopher M. Dobson, Tuomas P. J. Knowles, Erwin De Genst, Ralph A. Sperling, David A. Weitz, Jeremy J. Agresti
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14746-14751
The crucial early stages of amyloid growth, in which normally soluble proteins are converted into fibrillar nanostructures, are challenging to study using conventional techniques yet are critical to the protein aggregation phenomena implicated in man
Autor:
Tuomas P. J. Knowles, Christopher M. Dobson, Duncan A. White, Alexander K. Buell, Mark E. Welland
Publikováno v:
Journal of the American Chemical Society. 132:5170-5175
The physicochemical parameters of biomolecules are the key determinants of the multitude of processes that govern the normal and aberrant behavior of living systems. A particularly important aspect of such behavior is the role it plays in the self-as
Publikováno v:
Rheologica Acta. 46:531-537
The shear rheological properties of suspensions of gelled agar fibres in a low viscosity Newtonian matrix fluid were investigated. Two classes of fibres, low aspect ratio fibres and high aspect ratio fibres with an aspect ratio of the order of 10 and
Autor:
Emma V. Yates, Paolo Arosio, Erwin De Genst, Therese W. Herling, Christopher M. Dobson, Francesco A. Aprile, Thomas Müller, Duncan A. White, Luke Rajah, Samuel I. A. Cohen, Tuomas P. J. Knowles, Yingbo Zhang, Michele Vendruscolo, Sara Linse
Publikováno v:
ACS nano. 10(1)
Characterizing the sizes and interactions of macromolecules under native conditions is a challenging problem in many areas of molecular sciences, which fundamentally arises from the polydisperse nature of biomolecular mixtures. Here, we describe a mi
We present an approach for interfacing an electromechanical sensor with a microfluidic device for the accurate quantification of the dry mass of analytes within microchannels. We show that depositing solutes onto the active surface of a quartz crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec534aa8b659d4c537be6f5de1432992
Autor:
Eugene M. Terentjev, Samuel I. A. Cohen, Tuomas P. J. Knowles, Alexander K. Buell, Christopher M. Dobson, Michele Vendruscolo, C. H. Yoon, David A. Weitz, Luke Rajah, Duncan A. White, Reisa A. Sperling
Publikováno v:
Physical review letters. 112(9)
We consider the spatial dependence of filamentous protein self-assembly. Through studying the cases where the spreading of aggregated material is dominated either by diffusion or by growth, we derive analytical results for the spatial evolution of fi
Autor:
Mark E. Welland, Tuomas P. J. Knowles, Anne Dhulesia, Christopher M. Dobson, Duncan A. White, Alexander K. Buell
Publikováno v:
Angewandte Chemie (International ed. in English). 51(21)
Solubility is a key requirement for the functioning of a protein within the complex network of cellular components. A class of highly debilitating disorders, including Alzheimer s and Parkinson s diseases, is related to the loss of solubility of pept