Zobrazeno 1 - 10
of 573
pro vyhledávání: '"Duncan, Steele"'
Autor:
Chrispin Chaguza, Innocent Chibwe, David Chaima, Patrick Musicha, Latif Ndeketa, Watipaso Kasambara, Chimwemwe Mhango, Upendo L. Mseka, Joseph Bitilinyu-Bangoh, Bernard Mvula, Wakisa Kipandula, Patrick Bonongwe, Richard J. Munthali, Selemani Ngwira, Chikondi A. Mwendera, Akuzike Kalizang’oma, Kondwani C. Jambo, Dzinkambani Kambalame, Arox W. Kamng’ona, A. Duncan Steele, Annie Chauma-Mwale, Daniel Hungerford, Matthew Kagoli, Martin M. Nyaga, Queen Dube, Neil French, Chisomo L. Msefula, Nigel A. Cunliffe, Khuzwayo C. Jere
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Malawi experienced its deadliest Vibrio cholerae (Vc) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths reported between March 2022 and May 2023. Here, we use population genomics to investigate the attributes and o
Externí odkaz:
https://doaj.org/article/6b7cbc3890c14711a1a922c4cd6b9c0a
Autor:
Robyn-Lee Potgieter, Peter N. Mwangi, Milton T. Mogotsi, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Mapaseka L. Seheri, A. Duncan Steele, Jason M. Mwenda, Martin M. Nyaga
Publikováno v:
Viruses, Vol 15, Iss 12, p 2321 (2023)
Although the introduction of rotavirus vaccines has substantially contributed to the reduction in rotavirus morbidity and mortality, concerns persist about the re-emergence of variant strains that might alter vaccine effectiveness in the long term. T
Externí odkaz:
https://doaj.org/article/dd966503499b4d3bb2da10be3bd8b22e
Autor:
Tarun Saluja, Bishnu Rath Giri, Shipra Chaudhary, Dipesh Tamrakar, Piush Kanodia, Sonali Palkar, Sridhar Vemula, Suchada Chinaworapong, Bomi Kim, Birendra Prasad Gupta, Sue Kyoung Jo, Sanet Aspinall, Ganesh Kumar Rai, Duncan Steele, Jerome H. Kim, T. Anh Wartel, Sushant Sahastrabuddhe
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2149-2157 (2021)
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations,
Externí odkaz:
https://doaj.org/article/e12334ef5c8b46b391245a371de2d894
Autor:
Peter N. Mwangi, Robyn-Lee Potgieter, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Jason M. Mwenda, Milton T. Mogotsi, Kebareng Rakau, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga
Publikováno v:
Pathogens, Vol 12, Iss 5, p 658 (2023)
Africa has a high level of genetic diversity of rotavirus strains, which is suggested to be a possible reason contributing to the suboptimal effectiveness of rotavirus vaccines in this region. One strain that contributes to this rotavirus diversity i
Externí odkaz:
https://doaj.org/article/092bb1ddf66948888b519336b715ae59
Autor:
Kebareng G. Rakau, Martin M. Nyaga, Maemu P. Gededzha, Jason M. Mwenda, M. Jeffrey Mphahlele, L. Mapaseka Seheri, A. Duncan Steele
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background G12 rotaviruses were first observed in sub-Saharan Africa in 2004 and since then have continued to emerge and spread across the continent and are reported as a significant human rotavirus genotype in several African countries, bot
Externí odkaz:
https://doaj.org/article/daa3eb624ee94be2afd83e9e7b0bcf2f
Autor:
Joshua Ndung’u Gikonyo, Betty Mbatia, Patrick W. Okanya, George F.O. Obiero, Carlene Sang, Duncan Steele, James Nyangao
Publikováno v:
International Journal of Infectious Diseases, Vol 100, Iss , Pp 434-440 (2020)
Background: Rotaviruses are primary etiological agents of gastroenteritis in young children. In Kenya, G1P8 monovalent vaccine (Rotarix) was introduced in July 2014 for mandatory vaccination of all newborns at 6 and 10 weeks of age. Since then, no st
Externí odkaz:
https://doaj.org/article/53264c50f5c140db83ad411d86569733
Autor:
Peter N. Mwangi, Robyn-Lee Potgieter, Julia Simwaka, Evans M. Mpabalwani, Jason M. Mwenda, Milton T. Mogotsi, Nonkululeko Magagula, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga
Publikováno v:
Viruses, Vol 15, Iss 2, p 501 (2023)
The G2P[4] genotype is among the rotavirus strains that circulate commonly in humans. Several countries have reported its immediate upsurge after the introduction of rotavirus vaccination, raising concern about sub-optimal vaccine effectiveness again
Externí odkaz:
https://doaj.org/article/96579e4189d947bbb725374959353339
Autor:
Kebareng Rakau, Maemu Gededzha, Ina Peenze, Pengwei Huang, Ming Tan, Andrew Duncan Steele, Luyanda Mapaseka Seheri
Publikováno v:
Viruses, Vol 14, Iss 12, p 2735 (2022)
Objectives: Recently, histo-blood group antigens (HBGAs) have been identified as receptors or attachment factors of several viral pathogens. Among rotaviruses, HBGAs interact with the outer viral protein, VP4, which has been identified as a potential
Externí odkaz:
https://doaj.org/article/ff73e6897e5b4fac82cb1fc80820dac3
Autor:
Frederick N. Were, Khuzwayo C. Jere, George E. Armah, M. Jeffrey Mphahlele, Jason M. Mwenda, A. Duncan Steele
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1463 (2022)
The 13th African Rotavirus Symposium was held as a virtual event hosted by the University of Nairobi, Kenya and The Kenya Paediatric Association on 3rd and 4th November 2021. This biennial event organized under the auspices of the African Rotavirus N
Externí odkaz:
https://doaj.org/article/72ebc5502b00495ea35576590d551e18
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1536 (2022)
In recent years, there has been a resurgence of interest in the development of vaccines against Shigella driven by the growing awareness of the impact of this pathogen on global health [...]
Externí odkaz:
https://doaj.org/article/a787e0acd4e3445894bcdde877bead96