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Autor:
Chinmoy, Saha, Prarthana, Mohanraju, Andrew, Stubbs, Gaurav, Dugar, Youri, Hoogstrate, Gert-Jan, Kremers, Wiggert A, van Cappellen, Deborah, Horst-Kreft, Charlie, Laffeber, Joyce H G, Lebbink, Serena, Bruens, Duncan, Gaskin, Dior, Beerens, Maarten, Klunder, Rob, Joosten, Jeroen A A, Demmers, Dik, van Gent, Johan W, Mouton, Peter J, van der Spek, John, van der Oost, Peter, van Baarlen, Rogier, Louwen
Publikováno v:
Science Advances
CjeCas9 causes DNA damage in human cells.
CRISPR-Cas9 systems are enriched in human pathogenic bacteria and have been linked to cytotoxicity by an unknown mechanism. Here, we show that upon infection of human cells, Campylobacter jejuni secretes
CRISPR-Cas9 systems are enriched in human pathogenic bacteria and have been linked to cytotoxicity by an unknown mechanism. Here, we show that upon infection of human cells, Campylobacter jejuni secretes