Population pharmacokinetic modeling of dolutegravir/lamivudine to support a once-daily fixed-dose combination regimen in virologically suppressed adults living with HIV-1.

Autor: Chandasana H; Clinical Pharmacology Modeling & Simulation, GSK, Collegeville, Pennsylvania, USA., Singh R; Clinical Pharmacology Modeling & Simulation, GSK, Collegeville, Pennsylvania, USA., Adkison K; ViiV Healthcare, Durham, North Carolina, USA., Ait-Khaled M; ViiV Healthcare Ltd., Brentford, United Kingdom., Pene Dumitrescu T; Clinical Pharmacology Modeling & Simulation, GSK, Collegeville, Pennsylvania, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 May 02; Vol. 68 (5), pp. e0150423. Date of Electronic Publication: 2024 Apr 08.

Peritoneal Mesothelioma: Clinical and Therapeutic Aspects

Autor: Mihaela-Iustina Mesina-Botoran, Mihai Călin Ciorbagiu, Cosmin Vasile Obleaga, Cristian Mesina, Dumitrescu T

Mesothelioma is a very rare malignant disease that originates from mesothelial cells that line the serosa: pleura, peritoneum, pericardium, or testicular vaginal tunic. Peritoneal mesothelioma accounts for 7–10% of all mesotheliomas diagnosed, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab81b4b1b9cf8dc0619fd646f4ac7cec
https://doi.org/10.5772/intechopen.93536

A Novel Method for Studying the Pharmacokinetics of [¹⁴C]Umeclidinium After Application to the Axilla or Palm of Healthy Male Subjects.

Autor: Pene Dumitrescu, T¹, Santos, LL², Hughes, SC³, Pereira, AI³, Young, GC³, Hussey, E², Charlton, P², Baptiste‐Brown, S⁴, Stuart, JS², Vincent, V⁵, Marle, SP⁶, Schmith, VD¹

Publikováno v: CTS: Clinical & Translational Science. Aug2016, Vol. 9 Issue 4, p183-191. 9p.

Autophagy and Neovascularization in Colorectal Cancer.

Autor: USCATU, C. D.^1,2 daniel_uscatu@yahoo.com, DUMITRESCU, T.^3,4, DELIU, IONELA CRISTINA⁵, DUMITRESCU, ALEXANDRA⁶, SCHENKER, M.⁷, MIXICH, F.¹

Publikováno v: Current Health Sciences Journal. Jul-Sep2015, Vol. 41 Issue 3, p204-208. 5p.

Relative Bioavailability and Food Effect of GSK3640254 Tablet and Capsule Formulations in Healthy Participants.

Autor: Johnson M; ViiV Healthcare, Research Triangle Park, North Carolina, USA., Pene Dumitrescu T; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Joshi SR; ViiV Healthcare, Branford, Connecticut, USA., Mathew A; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Bainbridge V; GlaxoSmithKline, Brentford, UK., Zhan J; GlaxoSmithKline, Collegeville, Pennsylvania, USA., Lataillade M; ViiV Healthcare, Branford, Connecticut, USA.

Publikováno v: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 May; Vol. 11 (5), pp. 632-639. Date of Electronic Publication: 2022 Jan 07.