Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype.

Autor: Whitehall, VLJ, Dumenil, TD, McKeone, DM, Bond, CE, Bettington, ML, Buttenshaw, RL, Bowdler, L, Montgomery, GW, Wockner, LF, Leggett, BA

Publikováno v: Epigenetics; Nov2014, Vol. 9 Issue 11, p1454-1460, 7p

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.

Autor: Bond CE; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., McKeone DM; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kalimutho M; Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Bettington ML; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Envoi Specialist Pathologists, Brisbane, Queensland, Australia.; School of Medicine, University of Queensland, Brisbane, Queensland, Australia., Pearson SA; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Dumenil TD; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Wockner LF; Cancer and Population Studies, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Burge M; Department of Oncology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia., Leggett BA; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Medicine, University of Queensland, Brisbane, Queensland, Australia.; Department of Gastroenterology and Hepatology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia., Whitehall VL; Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Medicine, University of Queensland, Brisbane, Queensland, Australia.; Pathology Queensland, Brisbane, Queensland, Australia.

Publikováno v: Oncotarget [Oncotarget] 2016 Oct 25; Vol. 7 (43), pp. 70589-70600.