Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dulcie Lautu-Gumal"'
Autor:
Sarah Charnaud, Jacob E. Munro, Lucie Semenec, Ramin Mazhari, Jessica Brewster, Caitlin Bourke, Shazia Ruybal-Pesántez, Robert James, Dulcie Lautu-Gumal, Harin Karunajeewa, Ivo Mueller, Melanie Bahlo
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.
Externí odkaz:
https://doaj.org/article/1253400878aa4613b58d44f5bfe36819
Autor:
Dulcie Lautu-Gumal, Zahra Razook, Tamarah Koleala, Elma Nate, Samuel McEwen, Diana Timbi, Manuel W. Hetzel, Evelyn Lavu, Nakapi Tefuarani, Leo Makita, James Kazura, Ivo Mueller, William Pomat, Moses Laman, Leanne J. Robinson, Alyssa E. Barry
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 188-193 (2021)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated with delayed parasite clearance hav
Externí odkaz:
https://doaj.org/article/198619d3abfe4e2bbb6d7c0403e93cc4
Autor:
Abebe A. Fola, Eline Kattenberg, Zahra Razook, Dulcie Lautu-Gumal, Stuart Lee, Somya Mehra, Melanie Bahlo, James Kazura, Leanne J. Robinson, Moses Laman, Ivo Mueller, Alyssa E. Barry
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-15 (2020)
Abstract Background Genomic surveillance of malaria parasite populations has the potential to inform control strategies and to monitor the impact of interventions. Barcodes comprising large numbers of single nucleotide polymorphism (SNP) markers are
Externí odkaz:
https://doaj.org/article/47c2a8a7586e429bb5e17b5cb1a7b59f
Autor:
Elma Nate, Samuel McEwen, Nakapi Tefuarani, James W. Kazura, William Pomat, Leanne J. Robinson, Zahra Razook, Tamarah Koleala, Dulcie Lautu-Gumal, Alyssa E. Barry, Diana Timbi, Evelyn Lavu, Manuel W Hetzel, Leo Makita, Ivo Mueller, Moses Laman
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss, Pp 188-193 (2021)
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss, Pp 188-193 (2021)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated with delayed parasite clearance hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb796ee5e83e844e32d47f712daaf9
https://doi.org/10.1016/j.ijpddr.2021.06.004
https://doi.org/10.1016/j.ijpddr.2021.06.004
Autor:
Céline Barnadas, Maria Ome-Kaius, Alyssa E. Barry, Ivo Mueller, Abebe A. Fola, Peter Siba, James W. Kazura, Cristian Koepfli, Charlie Jennison, Johanna H Kattenberg, Zahra Razook, Leanne J. Robinson, Dulcie Lautu-Gumal, Raksmei Keo, Ingrid Felger
Publikováno v:
Mol Ecol
Monitoring the genetic structure of pathogen populations may be an economical and sensitive approach to quantify the impact of control on transmission dynamics, highlighting the need for a better understanding of changes in population genetic paramet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e208d6958672f573c48d5ebaf4670b5
https://doi.org/10.1111/mec.15654
https://doi.org/10.1111/mec.15654
Autor:
Sarah Charnaud, Jacob E. Munro, Lucie Semenec, Ramin Mazhari, Jessica Brewster, Caitlin Bourke, Shazia Ruybal-Pesántez, Robert James, Dulcie Lautu-Gumal, Harin Karunajeewa, Ivo Mueller, Melanie Bahlo
Publikováno v:
Communications biology. 5(1)
The CYP2D6 enzyme is estimated to metabolize 25% of commonly used pharmaceuticals and is of intense pharmacogenetic interest due to the polymorphic nature of the CYP2D6 gene. Accurate allele typing of CYP2D6 has proved challenging due to frequent cop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85c297e2b924d7ce119017590031dff
https://pubmed.ncbi.nlm.nih.gov/35217695
https://pubmed.ncbi.nlm.nih.gov/35217695
Autor:
Melanie Bahlo, Moses Laman, Alyssa E. Barry, Abebe A. Fola, Ivo Mueller, Zahra Razook, Somya Mehra, Didier Menard, Digjaya Utama, Leanne J. Robinson, Dulcie Lautu-Gumal, James W. Kazura, Brittany Gilchrist
Malaria parasite genomes have been generated predominantly using short read sequencing technology which can be slow, requires advanced laboratory training and does not adequately interrogate complex genomic regions that harbour important malaria viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48dc506d508b883d40572c49c932e7d8
https://doi.org/10.1101/2020.12.17.423341
https://doi.org/10.1101/2020.12.17.423341
Autor:
Somya Mehra, Eline Kattenberg, Leanne J. Robinson, Dulcie Lautu-Gumal, James W. Kazura, Abebe A. Fola, Stuart Lee, Ivo Mueller, Alyssa E. Barry, Zahra Razook, Moses Laman, Melanie Bahlo
Publikováno v:
Malaria Journal
Malaria Journal, Vol 19, Iss 1, Pp 1-15 (2020)
Malaria Journal, Vol 19, Iss 1, Pp 1-15 (2020)
Background Genomic surveillance of malaria parasite populations has the potential to inform control strategies and to monitor the impact of interventions. Barcodes comprising large numbers of single nucleotide polymorphism (SNP) markers are accurate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50cf5e3f87c5b7133afe4322c34c2df
https://pubmed.ncbi.nlm.nih.gov/33081815
https://pubmed.ncbi.nlm.nih.gov/33081815