Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dulce Alonso"'
Autor:
Eduardo Campos-Chavez, Sneha Paul, Zunwu Zhou, Dulce Alonso, Anjali R. Verma, Jingyi Fei, Alfonso Mondragón
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract T-box riboswitches are noncoding RNA elements involved in genetic regulation of most Gram-positive bacteria. They regulate amino acid metabolism by assessing the aminoacylation status of tRNA, subsequently affecting the transcription or tran
Externí odkaz:
https://doaj.org/article/0af80516b9e14819b7c238fbf849483c
Autor:
Jiacheng Zhang, Bhaskar Chetnani, Eric D Cormack, Dulce Alonso, Wei Liu, Alfonso Mondragón, Jingyi Fei
Publikováno v:
eLife, Vol 7 (2018)
T-box riboswitches are cis-regulatory RNA elements that regulate the expression of proteins involved in amino acid biosynthesis and transport by binding to specific tRNAs and sensing their aminoacylation state. While the T-box modular structural elem
Externí odkaz:
https://doaj.org/article/31ea41cbdfdd4781a946d6e0dd8a7d47
Autor:
Dulce Alonso, Alfonso Mondragón
Publikováno v:
Biochemical Society Transactions. 49:1529-1535
Ribozymes are folded catalytic RNA molecules that perform important biological functions. Since the discovery of the first RNA with catalytic activity in 1982, a large number of ribozymes have been reported. While most catalytic RNA molecules act alo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bab7871ba728ddb221c4e0a9cbd4ec
https://doi.org/10.1042/bst20200465
https://doi.org/10.1042/bst20200465
Autor:
Dulce Alonso, Aprajita Garg, Kirk W. Deitsch, Choukri Ben Mamoun, Donna Wesolowski, Sidney Altman
Publikováno v:
Proceedings of the National Academy of Sciences. 112:11935-11940
Identification and genetic validation of new targets from available genome sequences are critical steps toward the development of new potent and selective antimalarials. However, no methods are currently available for large-scale functional analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc62e4e46fcce76bbe4f540f2691f3e5
https://doi.org/10.1073/pnas.1515864112
https://doi.org/10.1073/pnas.1515864112
Publikováno v:
Bioconjugate Chemistry. 24:1186-1190
When suitably labeled bulk tRNAs are transfected into cells they give rise to FRET (fluorescence resonance energy transfer) signals via binding to ribosomes that provide a measure of total protein synthesis. Application of this approach to monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d38e09f04741d28936927ebe4ca109
https://doi.org/10.1021/bc400062d
https://doi.org/10.1021/bc400062d
Autor:
Elena Junquera, Mar Martín-Fontecha, Mariola Tortosa, Emilio Aicart, Bellinda Benhamú, Alma Viso, Silvia Ortega-Gutiérrez, Ana M. Gamo, María F. Martínez-Esperón, Henar Vázquez-Villa, María L. López-Rodríguez, Dulce Alonso, Roberto Fernández de la Pradilla
Publikováno v:
ACS Medicinal Chemistry Letters. 1:249-253
In this work, we report the design and synthesis of a set of fluorescent probes targeting the human 5-HT1A receptor (h5-HT1AR). Among the synthesized compounds, derivative 4 deserves special attention as being a high-affinity ligand (Ki = 2 nM) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d291bd5f1370b87d3b8970378c28af
https://doi.org/10.1021/ml100053y
https://doi.org/10.1021/ml100053y
Autor:
Oscar Llorca, Rafael Núñez-Ramírez, Sonia Huecas, Claudia Schaffner-Barbero, Dulce Alonso, María L. López-Rodríguez, Antonio J. Martin-Galiano, Laura B. Ruiz-Avila, José Manuel Andreu
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
20 p.-8 fig.-5 fig. supl.-1 tab. supl.
Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation an
Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ca13ab291e60fc3f2d2e27516da3fe
https://doi.org/10.1074/jbc.m109.094722
https://doi.org/10.1074/jbc.m109.094722
Publikováno v:
Tetrahedron Letters. 48:907-910
New 1-formamido-2-siloxy-1,3-butadienes have been generated from 1,3-dichloroacetone by means of phosphorane formation, formamido substitution, Wittig olefination and silylation. The procedure demonstrates the utility and versatility of this methodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3808d6aa445291a0c14d2db4c92fc16f
https://doi.org/10.1016/j.tetlet.2006.12.039
https://doi.org/10.1016/j.tetlet.2006.12.039
Autor:
Ana Marquina, Jesús Jiménez-Barbero, Moisés Balabasquer, Sandra Blasco-Benito, Nagore I. Marín-Ramos, Silvia Ortega-Gutiérrez, Henar Vázquez-Villa, María L. López-Rodríguez, Ángeles Canales, Jaime Moscoso del Prado, Dulce Alonso, Mar Martín-Fontecha, Clara Andradas, Cristina Sánchez, Francisco J. Ortega-Nogales, Eduardo Pérez-Gómez
Publikováno v:
Journal of medicinal chemistry. 58(9)
Angiogenesis is a requirement for the sustained growth and proliferation of solid tumors, and the development of new compounds that induce a sustained inhibition of the proangiogenic signaling generated by tumor hypoxia still remains as an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71de1ed03a7cedf7e0a65156638fb27
https://pubmed.ncbi.nlm.nih.gov/25906180
https://pubmed.ncbi.nlm.nih.gov/25906180