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Differences in target cell DNA fragmentation induced by mouse cytotoxic T lymphocytes and natural killer cells

Autor: Duke, R. C., J. John Cohen, Chervenak, R.

Publikováno v: Scopus-Elsevier

Fragmentation of YAC-1 target cell DNA during cytolysis mediated by mouse natural killer (NK) cells and cytotoxic T lymphocytes (CTL) was compared. Cleavage of nuclear chromatin was always an extensive and early event in CTL-mediated cytolysis, where

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81830f691c5aa28b76c5e4491fee9da
https://doi.org/10.4049/jimmunol.137.5.1442

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Periodical

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis.

Autor: Duke, R C, Chervenak, R, Cohen, J J

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; October 1983, Vol. 80 Issue: 20 p6361-6365, 5p

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Periodical

Apoptosis and Programmed Cell Death in Immunity

Autor: Cohen, J J, Duke, R C, Fadok, V A, Sellins, K S

Publikováno v: Annual Review of Immunology; April 1992, Vol. 10 Issue: 1 p267-293, 27p

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Periodical

Differential effects of staphylococcal toxic shock syndrome toxin-1 on B cell apoptosis.

Autor: Hofer, M F, Newell, K, Duke, R C, Schlievert, P M, Freed, J H, Leung, D Y

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; May 1996, Vol. 93 Issue: 11 p5425-5430, 6p

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Periodical

Self recognition by T cells. I. Bystander killing of target cells bearing syngeneic MHC antigens.

Autor: Duke, R C

Publikováno v: The Journal of Experimental Medicine; July 1989, Vol. 170 Issue: 1 p59-71, 13p

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Periodical

Purified perforin induces target cell lysis but not DNA fragmentation.

Autor: Duke, R C, Persechini, P M, Chang, S, Liu, C C, Cohen, J J, Young, J D

Publikováno v: The Journal of Experimental Medicine; October 1989, Vol. 170 Issue: 4 p1451-1456, 6p

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Cytotoxic lymphocyte-derived lytic granules do not induce DNA fragmentation in target cells

Autor: Duke, R. C., Sellins, K. S., J. John Cohen

Publikováno v: Scopus-Elsevier

When target cells are exposed to CTL, they very quickly sustain nuclear damage, including DNA cleavage, and then they lyse. Nuclear damage of this type is not seen when cells are killed by antibody and C. The role of nuclear damage in the T cell-medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5ba37c3b1a27d11ef53df58bd2d914
http://www.scopus.com/inward/record.url?eid=2-s2.0-0023692859&partnerID=MN8TOARS