Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Duk Su Koh"'
Autor:
Duk-Su Koh, Anastasiia Stratiievska, Subhashis Jana, Shauna C Otto, Teresa M Swanson, Anthony Nhim, Sara Carlson, Marium Raza, Ligia Araujo Naves, Eric N Senning, Ryan A Mehl, Sharona E Gordon
Publikováno v:
eLife, Vol 12 (2024)
Ligands such as insulin, epidermal growth factor, platelet-derived growth factor, and nerve growth factor (NGF) initiate signals at the cell membrane by binding to receptor tyrosine kinases (RTKs). Along with G-protein-coupled receptors, RTKs are the
Externí odkaz:
https://doaj.org/article/4da9d7ab97974baea2685bfc3abbcc20
Autor:
Tae-Don Kim, Hong-Ryul Jung, Sang-Hwan Seo, Se-Chan Oh, Youngho Ban, Xiaoxia Tan, Jung Min Kim, Sang Hyun Lee, Duk-Su Koh, Haiyoung Jung, Young-Jun Park, Suk Ran Yoon, Junsang Doh, Sang-Jun Ha, Inpyo Choi, Philip D. Greenberg
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Regulation of intracellular Ca2+ signaling is a major determinant of CD8+ T cell responsiveness, but the mechanisms underlying this regulation of Ca2+ levels, especially in naïve CD8+ T cells, are not fully defined. Here, we showed that mic
Externí odkaz:
https://doaj.org/article/30c9bb05268048c4babaae073c535db7
Publikováno v:
BioTechniques, Vol 55, Iss 1, Pp 34-37 (2013)
Here we present a convenient method for easy hand selection of enzymatically isolated small tissues such as islets of Langerhans. Islets are continuously collected in a micropipette tip connected to a peristaltic pump. After entering the conical micr
Externí odkaz:
https://doaj.org/article/f9abf7cae8124067aad4eb8af1a528ec
Publikováno v:
Proc Natl Acad Sci U S A
The pineal gland secretes melatonin principally at night. Regulated by norepinephrine released from sympathetic nerve terminals, adrenergic receptors on pinealocytes activate aralkylamine N-acetyltransferase that converts 5-hydroxytryptamine (5-HT, s
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144432 (2015)
Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) of the plasma membrane by phospholipase C (PLC) generates two critical second messengers, inositol-1,4,5-trisphosphate and diacylglycerol. For the enzymatic reaction, PIP2 binds to positively
Externí odkaz:
https://doaj.org/article/6957131b1439410bb6b999d2668420c6
Publikováno v:
Proc Natl Acad Sci U S A
β-arrestins regulate many cellular functions including intracellular signaling and desensitization of G protein–coupled receptors (GPCRs). Previous studies show that β-arrestin signaling and receptor endocytosis are modulated by the plasma membra
Publikováno v:
Proceedings of the National Academy of Sciences. 118
β-arrestins regulate many cellular functions including intracellular signaling and desensitization of G protein-coupled receptors (GPCRs). Previous studies show that β-arrestin signaling and receptor endocytosis are modulated by the plasma membrane
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81893 (2013)
Alcohol abuse is a major cause of pancreatitis. However alcohol toxicity has not been fully elucidated in the pancreas and little is known about the effect of alcohol on pancreatic ducts. We report the molecular mechanisms of ethanol-induced damage o
Externí odkaz:
https://doaj.org/article/77e40e486c704657b5166b0aea0ea87e
Autor:
Jongyun Myeong, Byung-Chang Suh, Seung-Ryoung Jung, Bertil Hille, Jun-Hee Yeon, Duk Su Koh, Lizbeth de la Cruz
Publikováno v:
Journal of General Physiology. 152
The dynamic metabolism of membrane phosphoinositide lipids involves several cellular compartments including the ER, Golgi, and plasma membrane. There are cycles of phosphorylation and dephosphorylation and of synthesis, transfer, and breakdown. The s
Publikováno v:
J Pineal Res
INTRODUCTION: At night, the pineal gland produces the indoleamines, melatonin, N-acetylserotonin (NAS), and N-acetyltryptamine (NAT). Melatonin is accepted as a hormone of night. Could NAS and NAT serve that role too? METHODS: Concentration-response