Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dugarmaa Ulzii"'
Autor:
Masutaka Furue, Dugarmaa Ulzii, Takeshi Nakahara, Gaku Tsuji, Kazuhisa Furue, Akiko Hashimoto-Hachiya, Makiko Kido-Nakahara
Publikováno v:
Allergology International, Vol 69, Iss 3, Pp 412-416 (2020)
Atopic dermatitis (AD) is a common eczematous skin disorder characterized by skin inflammation, barrier disruption, chronic pruritus and marked scratching. Th2 cytokines, especially IL-13, play a pathogenic role in AD. IL-13 signals via a heterodimer
Externí odkaz:
https://doaj.org/article/d85247d5c0504bf8bfba455a73a0ffac
Publikováno v:
Iranian Journal of Immunology, Vol 16, Iss 2, Pp 97-107 (2019)
Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies t
Externí odkaz:
https://doaj.org/article/fbd977b951014a1395d3a28a52ecec9c
Autor:
Masutaka Furue, Takahito Chiba, Gaku Tsuji, Dugarmaa Ulzii, Makiko Kido-Nakahara, Takeshi Nakahara, Takafumi Kadono
Publikováno v:
Allergology International, Vol 66, Iss 3, Pp 398-403 (2017)
Atopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic skin disorder mostly associated with IgE elevation and skin barrier dysfunction due to decreased filaggrin expression. The lesional skin of AD exhibits Th2- a
Externí odkaz:
https://doaj.org/article/0e79bab2e2aa4d2d88cde3366653592d
Publikováno v:
International Journal of Dermatology. 61
Autor:
Gaku Tsuji, Takeshi Nakahara, Dugarmaa Ulzii, Masutaka Furue, Makiko Kido-Nakahara, Akiko Hashimoto-Hachiya, Kazuhisa Furue
Publikováno v:
Allergology International, Vol 69, Iss 3, Pp 412-416 (2020)
Atopic dermatitis (AD) is a common eczematous skin disorder characterized by skin inflammation, barrier disruption, chronic pruritus and marked scratching. Th2 cytokines, especially IL-13, play a pathogenic role in AD. IL-13 signals via a heterodimer
Autor:
Takeshi Nakahara, Kazuhisa Furue, Dugarmaa Ulzii, Masutaka Furue, Gaku Tsuji, Yen Hai Vu, Takamichi Ito, Makiko Kido-Nakahara
Publikováno v:
Immunology
Despite sharing interleukin‐4 receptor α (IL‐4Rα) in their signaling cascades, IL‐4 and IL‐13 have different functions in atopic inflammation. IL‐13 preferentially participates in the peripheral tissues because tissue‐resident group 2 i
Autor:
Masutaka Furue, Takeshi Nakahara, Makiko Kido-Nakahara, Gaku Tsuji, Yen Hai Vu, Dugarmaa Ulzii
Publikováno v:
Current Treatment Options in Allergy. 6:200-210
To summarize recent topics on type 2 signatures in atopic dermatitis (AD). Therapeutic success of anti-IL-4 receptor antibody dupilumab does suggest that type 2 cytokines IL-4 and IL-13 have pivotal roles in the pathogenesis of AD. Lesional skin of A
Autor:
Gaku Tsuji, Masutaka Furue, Kei Fujishima, Makiko Kido-Nakahara, Takahito Chiba, Sawako Sakai, Dugarmaa Ulzii, Sho Miake, Takeshi Nakahara
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Endothelin-1 (ET-1) is well known as the most potent vasoconstrictor, and can evoke histamine-independent pruritus. Recently, its involvement in cutaneous inflammation has begun to draw attention. The upregulation of ET-1 expression in the epidermis
Autor:
Kazuhisa Furue, Gaku Tsuji, Masutaka Furue, Yuka Tanaka, Dugarmaa Ulzii, Takamichi Ito, Takeshi Nakahara, Makiko Kido-Nakahara
Publikováno v:
The Journal of dermatologyReferences. 47(9)
Mechanical scratching, a common external stress affecting the skin, is induced by various causes, such as pruritus. Scratch injury to epidermal keratinocytes upregulates the production and release of chemokine (C-C motif) ligand 20 (CCL20) in vitro,
Autor:
Masutaka Furue, Gaku Tsuji, Dugarmaa Ulzii, Masaki Takemura, Makiko Kido-Nakahara, Bing Wang, Takeshi Nakahara, Fumitaka Ohno
Publikováno v:
AllergyREFERENCES. 76(1)
Background Endothelin-1 (EDN1) can evoke histamine-independent pruritus in mammals and is upregulated in the lesional epidermis of atopic dermatitis (AD). EDN1 increases the production of interleukin 25 (IL-25) from keratinocytes to accelerate T help