Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dug-Keun Lee"'
Autor:
Kyoung Baek Choi, Dug Keun Lee, Moon-Jong Noh, Guang Fan Chi, Youngsuk Yi, Chae-Lyul Lim, Seong-Jin Kim, In-Suk Oh, Young-Deog Cha, Hyeon-Youl Lee, Kwan Hee Lee, Jong-Pil Hyun, J. Kelly Ganjei, Sun U. Song, Jeoung-Uk Han
Publikováno v:
Tissue Engineering. 11:1516-1526
The purpose of this study was to investigate the efficacy of cartilage regeneration when using a mixture of transforming growth factor-beta1 (TGF-beta1)-producing human chondrocytes (hChon-TGF-beta1) and primary human chondrocytes (hChon) ("mixed cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d622a4eaf9b9e4f0f6ace9a85f567f
https://doi.org/10.1089/ten.2005.11.1516
https://doi.org/10.1089/ten.2005.11.1516
Autor:
Kyoung Baek Choi, Dug Keun Lee, Jeannie Kim, Chae-Lyul Lim, Guang Fan Chi, Eun Byul Lee, Kwan Hee Lee, In Suk Oh, Sally Hwang, Youngsuk Yi, Sun U. Song, Moon Jong Noh, Vivian Yip, Hyeon-Youl Lee, Jong-Pil Hyun
Publikováno v:
Tissue Engineering. 11:310-318
One of the most important factors in the production of cartilage is transforming growth factor beta1 (TGF-beta1). To obtain sustained release of TGF-beta1, a cell-mediated gene therapy technique was introduced. We infected chondrocytes with a retrovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965d0293d7df5658ff9a1767f22d94a2
https://doi.org/10.1089/ten.2005.11.310
https://doi.org/10.1089/ten.2005.11.310
Autor:
Youngsuk Yi, Lillian Yun, Sung Ho Hahm, Kwan Hee Lee, Sally Hwang, Moon Jong Noh, Dug Keun Lee
Publikováno v:
Journal of Virological Methods. 121:127-136
Retroviral vectors have been widely used in gene therapy due to their simple genomic structure and high transduction efficiency. We report a construction of Moloney murine sarcoma virus (MoMSV) and Moloney murine leukemia virus (MoMLV) hybrid-based r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5708ad89a0bd1e7ac50bf1ee18a09dc2
https://doi.org/10.1016/j.jviromet.2004.05.014
https://doi.org/10.1016/j.jviromet.2004.05.014
Autor:
Ronald A. Morton, Dug Keun Lee, Isaac Yi Kim, Seth P. Lerner, Dong Hyeon Lee, Seong-Jin Kim, Wun-Jae Kim, Moses M. Kim
Publikováno v:
Cancer Research. 64:7355-7360
Bone morphogenetic proteins (BMPs), potential regulators of cellular growth and metastasis that signal through an interaction with plasma membrane receptors, have been suggested to be important regulators of malignant cells. The present study was car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc9fe735c3825ffddfb9813a5b04457
https://doi.org/10.1158/0008-5472.can-04-0154
https://doi.org/10.1158/0008-5472.can-04-0154
Autor:
Isaac Yi Kim, Han Jong Ahn, Dong Hyeon Lee, Ronald A. Morton, Moses M. Kim, Seong-Jin Kim, Dug Keun Lee
Publikováno v:
Oncogene. 23:7651-7659
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta superfamily and signal through a number of membrane receptors. We have previously demonstrated that the loss of expression of BMP receptors (BMPRs) type IA, -IB, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39379416fb9a561984da415c82ab71f
https://doi.org/10.1038/sj.onc.1207924
https://doi.org/10.1038/sj.onc.1207924
Autor:
Sae Ra Lee, Angelina Felici, James G. McNally, Tatiana S. Karpova, Byung-Chul Kim, Ho Jae Lee, Seok Hee Park, Dug Keun Lee, Seong-Jin Kim
Publikováno v:
Molecular and Cellular Biology. 24:2251-2262
Smad7 inhibits responses mediated by transforming growth factor beta (TGF-beta) and acts in a negative-feedback loop to regulate the intensity or duration of the TGF-beta signal. However, the aberrant expression and continued presence of Smad7 may ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d15de94e77eae76fb725b09b694bd3
https://doi.org/10.1128/mcb.24.6.2251-2262.2004
https://doi.org/10.1128/mcb.24.6.2251-2262.2004
Publikováno v:
Journal of Biological Chemistry. 277:38557-38564
The human papillomavirus (HPV) oncoprotein E7 is implicated in the etiology of cervical cancer associated with infection by HPV. HPV-positive cells develop resistance to TGF-beta growth inhibitory activity through the inhibition of hypophosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f56efca9ae80a6a676b328f143f168a
https://doi.org/10.1074/jbc.m206786200
https://doi.org/10.1074/jbc.m206786200
Publikováno v:
Biochemical Pharmacology. 62:1439-1447
We studied the effect of DW2282-,[(S)-(+)-4-phenyl-1-[N-(4-aminobenzoyl)-indoline-5-sulfonyl-4,5-dihydro-2-imidazolone].hydrochloride], a newly developed anti-cancer agent, on cell proliferation, cell cycle progression, and induction of apoptosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb265f992107bbc6c81b6055f513a564
https://doi.org/10.1016/s0006-2952(01)00796-1
https://doi.org/10.1016/s0006-2952(01)00796-1
Autor:
Seok Hee Park, Youngsuk Yi, W. Tony Parks, Hye Seong Cho, Seong-Jin Kim, Cecile Lee, Yosef Shaul, Anita B. Roberts, Shin Geon Choi, Mark P. de Caestecker, Dug Keun Lee
Publikováno v:
Genes & Development. 15:455-466
Hepatitis B, one of the most common infectious diseases in the world, is closely associated with acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Many clinical investigations have revealed that hepatic fibrosis is an important co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d672155ded3a127f36b14ae5000ee9a
https://doi.org/10.1101/gad.856201
https://doi.org/10.1101/gad.856201
Publikováno v:
European Journal of Biochemistry. 268:565-572
The equilibrium binding and association kinetics of the fos-jun dimer (basic and leucine zipper domain) to the AP-1 DNA were studied using a quantitative assay. The basic-region and leucine zipper (bZip) domain of c-fos was expressed as a fusion prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f30505190ac9150540dd4bad7e66820
https://doi.org/10.1046/j.1432-1327.2001.01897.x
https://doi.org/10.1046/j.1432-1327.2001.01897.x