Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis.

Autor: Thiel J; Division of Rheumatology and Clinical Immunology, Medical University of Graz, Graz, Austria marta.rizzi@uniklinik-freiburg.de jens.thiel@medunigraz.at.; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Schmidt FM; Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Lorenzetti R; Division of Rheumatology and Clinical Immunology, Medical University of Graz, Graz, Austria.; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Troilo A; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Janowska I; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Nießen L; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Pfeiffer S; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Staniek J; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Benassini B; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Bott MT; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Korzhenevich J; Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Konstantinidis L; Department of Orthopedics and Trauma Surgery, University of Freiburg, Freiburg im Breisgau, Germany., Burgbacher F; Department of Orthopedics and Trauma Surgery, University of Freiburg, Freiburg im Breisgau, Germany., Dufner AK; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Frede N; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Voll RE; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.; Centre of Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Stuchly J; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Bakardjieva M; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Kalina T; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Smulski CR; Medical Physics Department, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Bariloche, Argentina., Venhoff N; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Rizzi M; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany marta.rizzi@uniklinik-freiburg.de jens.thiel@medunigraz.at.; Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.; Centre of Chronic Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2024 Oct 21; Vol. 83 (11), pp. 1536-1548. Date of Electronic Publication: 2024 Oct 21.