PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.

Autor: Jeung HC; MD Anderson Cancer Center, Houston, TX, USA; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Gangnam-Gu, Seoul, South Korea., Puentes R; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Aleshin A; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Indarte M; PHusis Therapeutics, La Jolla, CA, USA., Correa RG; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Bankston LA; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Layng FIAL; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Ahmed Z; MD Anderson Cancer Center, Houston, TX, USA., Wistuba I; MD Anderson Cancer Center, Houston, TX, USA., Yao Y; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Duenas DG; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Zhang S; MD Anderson Cancer Center, Houston, TX, USA., Meuillet EJ; PHusis Therapeutics, La Jolla, CA, USA., Marassi F; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Liddington RC; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA., Kirkpatrick L; PHusis Therapeutics, La Jolla, CA, USA., Powis G; Sanford Burnham Prebys Medical Discovery Institute Cancer Center, La Jolla, CA, USA; PHusis Therapeutics, La Jolla, CA, USA. Electronic address: gpowis@phusistherapeutics.com.

Publikováno v: Experimental cell research [Exp Cell Res] 2021 Dec 15; Vol. 409 (2), pp. 112930. Date of Electronic Publication: 2021 Nov 17.