Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Dudley K. Strickland"'
Autor:
Jackie M. Zhang, Dianaly T. Au, Hisashi Sawada, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Pengjun Wang, Brittany O. Aicher, Brian Hampton, Mary Migliorini, Fenge Ni, Adam E. Mullick, Mashhood M. Wani, Areck A. Ucuzian, Hong S. Lu, Selen C. Muratoglu, Alan Daugherty, Dudley K. Strickland
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor–related protein 1 (LRP1), a large endocytic signaling receptor that recogn
Externí odkaz:
https://doaj.org/article/ed0a8984fa804ee7ba6b0ca5af6a4865
Autor:
Lisa M. Leung, William E. Fondrie, Yohei Doi, J. Kristie Johnson, Dudley K. Strickland, Robert K. Ernst, David R. Goodlett
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Rapid diagnostics that enable identification of infectious agents improve patient outcomes, antimicrobial stewardship, and length of hospital stay. Current methods for pathogen detection in the clinical laboratory include biological culture,
Externí odkaz:
https://doaj.org/article/156f61f087a64257a20eeb277fb83d6c
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Hepatic inflammation is associated with the development of insulin resistance, which can perpetuate the disease state and may increase the risk of metabolic syndrome and diabetes. Despite recent advances, mechanisms linking hepatic inflammation and i
Externí odkaz:
https://doaj.org/article/d76786fdc8a149b1b12ab4d6e906b392
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
The metabolic syndrome is an escalating worldwide public health concern. Defined by a combination of physiological, metabolic, and biochemical factors, the metabolic syndrome is used as a clinical guideline to identify individuals with a higher risk
Externí odkaz:
https://doaj.org/article/337e8301816a43c49d17048188129ffe
Autor:
Jose Ruiz, Diana Kouiavskaia, Molly Migliorini, Susan Robinson, Evgueni L. Saenko, Natalia Gorlatova, Donghua Li, Daniel Lawrence, Bradley T. Hyman, Karl H. Weisgraber, Dudley K. Strickland
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1721-1731 (2005)
Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction with members of the LDL receptor family. ApoE exists as three common isoforms that have important distinct functional and biological properties. Two apoE isoforms, ap
Externí odkaz:
https://doaj.org/article/ccd16cc9ff0f46a5b185bb9560a19daf
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1859-1869 (2003)
Inhibitors of the human immunodeficiency virus (HIV)-1 protease have proven to be effective antiretroviral drugs. However, patients receiving these drugs develop serious metabolic abnormalities, including hypercholesterolemia. The objective of the pr
Externí odkaz:
https://doaj.org/article/de3037d26dbe46d892ea1e4eb7deb4b6
Autor:
Lennart Nilsson, Mats Gåfvels, Leena Musakka, Katharina Ensler, Dudley K. Strickland, Bo Angelin, Anders Hamsten, Per Eriksson
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 5, Pp 913-919 (1999)
The potential role of the very low density lipoprotein (VLDL) receptor in mediating VLDL-induced plasminogen activator inhibitor-1 (PAI-1) expression was studied in vitro. Cultured endothelial cells incubated with VLDL showed an increased secretion o
Externí odkaz:
https://doaj.org/article/7f34a73bfa334f6f9e9759ac046c73d9
Autor:
Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2255-2269
Deficiency in blood coagulation factor VIII (FVIII) results in life-threating bleeding (hemophilia A) treated by infusions of FVIII concentrates. To improve disease treatment, FVIII has been modified to increase its plasma half-life, which requires u
Autor:
Jackie M. Zhang, Dianaly T. Au, Hisashi Sawada, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Pengjun Wang, Brittany O. Aicher, Brian Hampton, Mary Migliorini, Fenge Ni, Adam E. Mullick, Mashhood M. Wani, Areck A. Ucuzian, Hong S. Lu, Selen C. Muratoglu, Alan Daugherty, Dudley K. Strickland
Publikováno v:
JCI insight.
Vascular smooth muscle cells (vSMC) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor-related protein 1 (LRP1), a large endocytic and signaling receptor that recog
Autor:
Joanna M Cooper, Aurelien Lathuiliere, John Dickson, Calina Glynn, Zhanyun Fan, Cameron Donahue, Mary Migliorini, Bradley T. Hyman, Dudley K Strickland
Publikováno v:
Alzheimer's & Dementia. 18