Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Dudley K, Strickland"'
Autor:
Jackie M. Zhang, Dianaly T. Au, Hisashi Sawada, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Pengjun Wang, Brittany O. Aicher, Brian Hampton, Mary Migliorini, Fenge Ni, Adam E. Mullick, Mashhood M. Wani, Areck A. Ucuzian, Hong S. Lu, Selen C. Muratoglu, Alan Daugherty, Dudley K. Strickland
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor–related protein 1 (LRP1), a large endocytic signaling receptor that recogn
Externí odkaz:
https://doaj.org/article/ed0a8984fa804ee7ba6b0ca5af6a4865
Autor:
Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2255-2269
Deficiency in blood coagulation factor VIII (FVIII) results in life-threating bleeding (hemophilia A) treated by infusions of FVIII concentrates. To improve disease treatment, FVIII has been modified to increase its plasma half-life, which requires u
Autor:
Lisa M. Leung, William E. Fondrie, Yohei Doi, J. Kristie Johnson, Dudley K. Strickland, Robert K. Ernst, David R. Goodlett
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Rapid diagnostics that enable identification of infectious agents improve patient outcomes, antimicrobial stewardship, and length of hospital stay. Current methods for pathogen detection in the clinical laboratory include biological culture,
Externí odkaz:
https://doaj.org/article/156f61f087a64257a20eeb277fb83d6c
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Hepatic inflammation is associated with the development of insulin resistance, which can perpetuate the disease state and may increase the risk of metabolic syndrome and diabetes. Despite recent advances, mechanisms linking hepatic inflammation and i
Externí odkaz:
https://doaj.org/article/d76786fdc8a149b1b12ab4d6e906b392
Autor:
Jackie M. Zhang, Dianaly T. Au, Hisashi Sawada, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Pengjun Wang, Brittany O. Aicher, Brian Hampton, Mary Migliorini, Fenge Ni, Adam E. Mullick, Mashhood M. Wani, Areck A. Ucuzian, Hong S. Lu, Selen C. Muratoglu, Alan Daugherty, Dudley K. Strickland
Publikováno v:
JCI insight.
Vascular smooth muscle cells (vSMC) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor-related protein 1 (LRP1), a large endocytic and signaling receptor that recog
Autor:
Joanna M Cooper, Aurelien Lathuiliere, John Dickson, Calina Glynn, Zhanyun Fan, Cameron Donahue, Mary Migliorini, Bradley T. Hyman, Dudley K Strickland
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
The metabolic syndrome is an escalating worldwide public health concern. Defined by a combination of physiological, metabolic, and biochemical factors, the metabolic syndrome is used as a clinical guideline to identify individuals with a higher risk
Externí odkaz:
https://doaj.org/article/337e8301816a43c49d17048188129ffe
Publikováno v:
Thrombosis and haemostasis. 122(11)
Numerous studies have revealed the involvement of fibrinogen in the inflammatory response. To explain the molecular mechanisms underlying fibrinogen-dependent inflammation, two bridging mechanisms have been proposed in which fibrin(ogen) bridges leuk
Correction: LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.
Autor:
Anna P Lillis, Selen Catania Muratoglu, Dianaly T Au, Mary Migliorini, Mi-Jeong Lee, Susan K Fried, Irina Mikhailenko, Dudley K Strickland
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147457 (2016)
Externí odkaz:
https://doaj.org/article/03c4d359873f48c88a6f24c5b9852c3c
Autor:
Dudley K. Strickland, David Peeney, William G. Stetler-Stevenson, Allison L. Arai, Selen C. Muratoglu, Mary Migliorini, Elizabeth Hahn-Dantona, Dianaly T. Au
Publikováno v:
Biochemistry
Matrix metalloprotease (MMP) activation contributes to the degradation of the extracellular matrix (ECM), resulting in a multitude of pathologies. Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifaceted endocytic and signaling rec