Peptide Inhibitors of the Interaction of the SARS-CoV-2 Receptor-Binding Domain with the ACE2 Cell Receptor

Autor: Bibilashvili, R. Sh., Sidorova, M. V., Dudkina, U. S., Palkeeva, M. E., Molokoedov, A. S., Kozlovskaya, L. I., Egorov, A. M., Ishmukhametov, A. A., Parfyonova, E.V.

Publikováno v: Biochemistry (Moscow) Supplement. Series B, Biomedical Chemistry

Computer simulation has been used to identify peptides that mimic the natural target of the SARS-CoV-2 coronavirus spike (S) protein, the angiotensin-converting enzyme type 2 (ACE2) cell receptor. Based on the structure of the complex of the protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a1ac98c8cab6e8c6c76cd1ff9868e
https://doi.org/10.1134/s199075082104003x

[Peptide inhibitors of the interaction of the SARS-CoV-2 receptor-binding domain with the ACE2 cell receptor].

Autor: Bibilashvili RS; National Medical Research Center for Cardiology, Moscow, Russia., Sidorova MV; National Medical Research Center for Cardiology, Moscow, Russia., Dudkina US; National Medical Research Center for Cardiology, Moscow, Russia., Palkeeva ME; National Medical Research Center for Cardiology, Moscow, Russia., Molokoedov AS; National Medical Research Center for Cardiology, Moscow, Russia., Kozlovskaya LI; Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products of the Russian Academy of Sciences, Moscow, Russia; Sechenov Moscow State Medical University, Moscow, Russia., Egorov AM; Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products of the Russian Academy of Sciences, Moscow, Russia; Lomonosov Moscow State University, Moscow, Russia., Ishmukhametov AA; Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products of the Russian Academy of Sciences, Moscow, Russia; Sechenov Moscow State Medical University, Moscow, Russia., Parfyonova YV; National Medical Research Center for Cardiology, Moscow, Russia.

Publikováno v: Biomeditsinskaia khimiia [Biomed Khim] 2021 May; Vol. 67 (3), pp. 244-250.