Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Dudka Jaroslaw"'
Autor:
Korga-Plewko Agnieszka, Ostrowska-Lesko Marta, Iwan Magdalena, Szponar Jaroslaw, Wrobel Andrzej, Cendrowska-Pinkosz Monika, Grzycka-Kowalczyk Luiza, Poleszak Ewa, Slaska Brygida, Dudka Jaroslaw, Chrapko Beata, Mandziuk Slawomir
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 35, Iss 1, Pp 34-40 (2022)
This manuscript reviews evidences underlying the estimation of risk of malignancy enhancement of advanced aggressive cancers as a result of the gamma radiation emitted by tracers used in PET diagnostics. We conclude that among many cancers, such a ph
Externí odkaz:
https://doaj.org/article/1c68573520a9481790e086304e7d52fc
Autor:
Dabrowska Anna Maria, Dudka Jaroslaw
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 34, Iss 3, Pp 160-163 (2021)
Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most fr
Externí odkaz:
https://doaj.org/article/73d2652d9e4c4d5ebf3450c24fb9a4d3
Autor:
Korga Agnieszka, Iwan Magdalena, Matosiuk Dariusz, Rzadkowska Marzena, Szacon Elzbieta, Humeniuk Ewelina, Sysa Marcin, Ostrowska Marta, Dudka Jaroslaw
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 33, Iss 1, Pp 1-5 (2020)
Doxorubicin cardiotoxicity is caused by various mechanisms, most importantly by oxidative stress originating in the mitochondria. Tirapazamine is a hypoxia-activated anticancer experimental drug. Both drugs in normoxia conditions undergo univalent re
Externí odkaz:
https://doaj.org/article/bcf6c979ee374184bb7f1240802f1bf5
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 32, Iss 1, Pp 18-22 (2019)
Hypoxic cancer cells are more aggressive and responsible for more efficient metastasis and recurrence. It seems worth-while, hence, to supplement current cytostatic drugs therapy (i.e. cisplatin) with hypoxia cytotoxic agents (i.e. tirapazamine), the
Externí odkaz:
https://doaj.org/article/bbe9472305d747a8907ed9c6f2d5032b
Autor:
Korga Agnieszka, Soroka Milena, Wicha Karolina, Humeniuk Ewelina, Adamczuk Grzegorz, Iwan Magdalena, Sysa Marcin, Dudka Jaroslaw
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 31, Iss 1, Pp 18-21 (2018)
One of the less known mechanisms of doxorubicin action is the effect on the functioning of the ubiquitin-proteasome degradation system (UPS). So far, the role of impaired proteasome activity in the development of anthracycline cardiomyopathy has not
Externí odkaz:
https://doaj.org/article/c72f8688a29d40beb01c9e31e65067bb
Autor:
Tereszkiewicz Sylwia, Matysiak Wlodzimierz, Mandziuk Slawomir, Korga Agnieszka, Oleksiejuk Malgorzata, Hejna Marcin, Korobowicz-Markiewicz Agnieszka, Iwan Magdalena, Dudka Jaroslaw
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 27, Iss 2, Pp 88-91 (2014)
The aim of the study was to verify the thesis that the cardiotoxic effects of doxorubicin are connected with activation of the ubiquitin - proteasome pathway followed by protein degradation. The expression of myocardial damage markers - fatty acid bi
Externí odkaz:
https://doaj.org/article/5497cf29b45b4a47adfac5cfed4eb36a
Autor:
Wnukowska Magdalena, Mandziuk Slawomir, Korga Agnieszka, Jodlowska-Jedrych Barbara, Matysiak Wlodzimierz, Halasa Justyna, Burdan Franciszek, Iwan Magdalena, Gieroba Renata, Dudka Jaroslaw
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 28, Iss 1, Pp 5-7 (2015)
The redox cycle triggered by one electron reduction of doxorubicin and tirapazamine - both anticancer agents - leads to superoxide production. This superoxide production itself removes one iron atom from the [4Fe-4S] cluster, being an active center o
Externí odkaz:
https://doaj.org/article/9f2879a32c564a98bf7f874238e9417a
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