Conjugation of peptides to short-acyl-chain ceramides for delivery across mucosal cell barriers.

Autor: Duclos RI Jr; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States. Electronic address: Richard.Duclos@childrens.harvard.edu., Blue KD; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States. Electronic address: bluekiara@gmail.com., Rufo MJ; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States. Electronic address: michael.j.rufo@gmail.com., Chen X; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States. Electronic address: Xiaoling.Chen@umassmed.edu., Guo JJ; Barnett Institute for Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, United States. Electronic address: J.Guo@northeastern.edu., Ma X; Barnett Institute for Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, United States. Electronic address: Ma.Xiaoy@husky.neu.edu., Lencer WI; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States; Harvard Digestive Diseases Center, Boston, MA 02115, United States. Electronic address: Wayne.Lencer@childrens.harvard.edu., Chinnapen DJF; Division of Gastroenterology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, United States; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, United States. Electronic address: Dan.Chinnapen@childrens.harvard.edu.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Apr 15; Vol. 30 (8), pp. 127014. Date of Electronic Publication: 2020 Feb 07.

Stereochemical Structure Activity Relationship Studies (S-SAR) of Tetrahydrolipstatin.

Autor: Liu X; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Wang Y; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Duclos RI Jr; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., O'Doherty GA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Feb 21; Vol. 9 (3), pp. 274-278. Date of Electronic Publication: 2018 Feb 21 (Print Publication: 2018).

Brain uptake and metabolism of the endocannabinoid anandamide labeled in either the arachidonoyl or ethanolamine moiety.

Autor: Hu K; Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115; Department of Biological Sciences, Kingsborough Community College, 2001 Oriental Boulevard, Brooklyn, NY 11235., Sonti S; Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115; Department of Biological Sciences, Kingsborough Community College, 2001 Oriental Boulevard, Brooklyn, NY 11235., Glaser ST; Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115; Department of Biological Sciences, Kingsborough Community College, 2001 Oriental Boulevard, Brooklyn, NY 11235., Duclos RI Jr; Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115; Department of Biological Sciences, Kingsborough Community College, 2001 Oriental Boulevard, Brooklyn, NY 11235., Gatley SJ; Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115; Department of Biological Sciences, Kingsborough Community College, 2001 Oriental Boulevard, Brooklyn, NY 11235. Electronic address: s.gatley@neu.edu.

Publikováno v: Nuclear medicine and biology [Nucl Med Biol] 2017 Feb; Vol. 45, pp. 43-50. Date of Electronic Publication: 2016 Nov 09.

17β-estradiol (E2) in membranes: Orientation and dynamic properties.

Autor: Guo JJ; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA. Electronic address: j.guo@neu.edu., Yang DP; Physics Department, College of the Holy Cross, 1 College Street, Worcester, MA 01610, USA., Tian X; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Vemuri VK; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Yin D; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Li C; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Duclos RI Jr; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Shen L; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Ma X; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Janero DR; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA., Makriyannis A; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA. Electronic address: a.makriyannis@neu.edu.

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Feb; Vol. 1858 (2), pp. 344-53. Date of Electronic Publication: 2015 Dec 01.

Integrity of (111)In-radiolabeled superparamagnetic iron oxide nanoparticles in the mouse.

Autor: Wang H; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115; Nanomedicine Science and Technology Center, Northeastern University, Boston, MA 02115., Kumar R; Nanomedicine Science and Technology Center, Northeastern University, Boston, MA 02115., Nagesha D; Nanomedicine Science and Technology Center, Northeastern University, Boston, MA 02115., Duclos RI Jr; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115., Sridhar S; Nanomedicine Science and Technology Center, Northeastern University, Boston, MA 02115., Gatley SJ; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115. Electronic address: s.gatley@neu.edu.

Publikováno v: Nuclear medicine and biology [Nucl Med Biol] 2015 Jan; Vol. 42 (1), pp. 65-70. Date of Electronic Publication: 2014 Sep 06.