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of 64
pro vyhledávání: '"Duckworth CA"'
Autor:
Evans, JP, Winiarski, BK, Sutton, PA, Jones, RP, Ressel, L, Duckworth, CA, Pritchard, DM, Lin, ZX, Vicky, FL, Tweedle, EM, Costello, E, Goldring, CE, Copple, IM, Park, BK, Palmer, DH, Kitteringham, NR
Publikováno v:
Oncotarget
© Evans et al. Nrf2 is a transcription factor that regulates cellular stress response and irinotecan-metabolising pathways. Its aberrant activity has been reported in a number of cancers, although relatively few studies have explored a role for Nrf2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c5a0f3d5005d2d5f8d85b80301049a22
http://livrepository.liverpool.ac.uk/3024449/1/25497-1005819-3-PB.pdf
http://livrepository.liverpool.ac.uk/3024449/1/25497-1005819-3-PB.pdf
Akademický článek
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Autor:
Than NW; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, United Kingdom; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, United Kingdom. Electronic address: nwthan@liverpool.ac.uk., Pritchard DM; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, United Kingdom. Electronic address: Mark.Pritchard@liverpool.ac.uk., Hughes DM; Department of Health Data Science, Institute of Population Health, The University of Liverpool, L7 3EA, United Kingdom. Electronic address: David.Hughes@liverpool.ac.uk., Duckworth CA; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, United Kingdom. Electronic address: C.A.Duckworth@liverpool.ac.uk., Wong H; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, United Kingdom. Electronic address: helen.wong1@nhs.net., Haq MU; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, United Kingdom; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, United Kingdom. Electronic address: Muneeb.Haq@liverpool.ac.uk., Sripadam R; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, United Kingdom. Electronic address: rajaram.sripadam@nhs.net., Myint AS; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, United Kingdom; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, United Kingdom. Electronic address: sun.myint@nhs.net.
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2024 Oct; Vol. 199, pp. 110465. Date of Electronic Publication: 2024 Jul 27.
Autor:
Wah Than N; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, UK.; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, UK., Mark Pritchard D; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, UK., Hughes DM; Department of Health Data Science, Institute of Population Health, The University of Liverpool, L7 3EA, UK., Shing Yu K; St. Luke's Cancer Centre, Royal Surrey Hospital, Guildford, Surrey, UK., Minnaar HS; St. Luke's Cancer Centre, Royal Surrey Hospital, Guildford, Surrey, UK., Dhadda A; Castle Hill Hospital, Castle Road, Cottingham HU16 5JQ, UK., Mills J; Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Rd, Nottingham NG5 1PB, UK., Folkesson J; Department of Surgery, Akademiska sjukhuset, Institute of Surgical Sciences, Uppsala University, 751 85 Uppsala, Sweden., Radu C; Department of Immunology, Genetics and Pathology, Experimental and Clinical Oncology, Uppsala University, 751 85 Uppsala, Sweden., Duckworth CA; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, UK., Wong H; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, UK., Ul Haq M; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, UK.; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, UK., Sripadam R; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, UK., Halling-Brown MD; St. Luke's Cancer Centre, Royal Surrey Hospital, Guildford, Surrey, UK., Stewart AJ; St. Luke's Cancer Centre, Royal Surrey Hospital, Guildford, Surrey, UK.; University of Surrey, Guildford, Surrey, UK., Sun Myint A; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, L69 3GE, UK.; The Clatterbridge Cancer Centre NHS Foundation Trust, 65 Pembroke Place, Liverpool L7 8YA, UK.
Publikováno v:
Clinical and translational radiation oncology [Clin Transl Radiat Oncol] 2024 Sep 06; Vol. 49, pp. 100851. Date of Electronic Publication: 2024 Sep 06 (Print Publication: 2024).
Autor:
Than NW; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom.; The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom., Pritchard DM; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom., Duckworth CA; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom., Hughes DM; Department of Health Data Science, Institute of Population Health, The University of Liverpool, Liverpool, United Kingdom., Wong H; The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom., Sripadam R; The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom., Myint AS; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Liverpool, United Kingdom.; The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom.
Publikováno v:
Journal of contemporary brachytherapy [J Contemp Brachytherapy] 2024 Apr; Vol. 16 (2), pp. 95-102. Date of Electronic Publication: 2024 Apr 23.
Autor:
Johnston LJ; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Barningham L; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Campbell EL; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Cerovic V; Institute of Molecular Medicine, RWTH University Hospital, Aachen, Germany., Duckworth CA; Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Luu L; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Wastling J; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; College of Health, Medicine and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, Middlesex, UK., Derricott H; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Coombes JL; Department of Infection Biology, Institute of Infection and Global Health & School of Veterinary Science, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK.
Publikováno v:
Discovery immunology [Discov Immunol] 2023 Oct 07; Vol. 2 (1), pp. kyad018. Date of Electronic Publication: 2023 Oct 07 (Print Publication: 2023).
Autor:
Gall L; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK., Jardi F; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium., Lammens L; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium., Piñero J; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), UPF, Barcelona, Spain., Souza TM; Department of Toxicogenomics, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands., Rodrigues D; Department of Toxicogenomics, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands., Jennen DGJ; Department of Toxicogenomics, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands., de Kok TM; Department of Toxicogenomics, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands., Coyle L; Boehringer Ingelheim International GmbH, Ridgefield, Connecticut, USA., Chung SW; Boehringer Ingelheim International GmbH, Ridgefield, Connecticut, USA., Ferreira S; Simcyp Division, Certara UK Limited, Sheffield, UK., Jo H; Simcyp Division, Certara UK Limited, Sheffield, UK., Beattie KA; Target and Systems Safety, Non-Clinical Safety, In Vivo/In Vitro Translation, GSK, Stevenage, UK., Kelly C; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Duckworth CA; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Pritchard DM; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Pin C; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Publikováno v:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Oct; Vol. 12 (10), pp. 1511-1528. Date of Electronic Publication: 2023 Sep 11.
Autor:
Wan Y; Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Adair K; Centre for Proteome Research, University of Liverpool, Liverpool, UK., Herrmann A; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Shan X; Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Xia L; Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Duckworth CA; Department of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Yu LG; Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. lgyu@liv.ac.uk.
Publikováno v:
Cell death & disease [Cell Death Dis] 2023 Aug 23; Vol. 14 (8), pp. 547. Date of Electronic Publication: 2023 Aug 23.
Autor:
Jardi F; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium. fjardi@its.jnj.com., Kelly C; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Teague C; GlaxoSmithKline, Non-Clinical Safety, Ware, UK., Fowler-Williams H; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Sevin DC; Omics Sciences, Genomic Sciences, GlaxoSmithKline, Heidelberg, Germany., Rodrigues D; Department of Toxicogenomics, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Jo H; Certara UK Limited, Simcyp Division, Sheffield, UK., Ferreira S; Certara UK Limited, Simcyp Division, Sheffield, UK., Herpers B; Crown Bioscience Netherlands, Leiden, The Netherlands., Van Heerden M; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium., de Kok T; Department of Toxicogenomics, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Pin C; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK., Lynch A; GlaxoSmithKline, Non-Clinical Safety, Ware, UK., Duckworth CA; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., De Jonghe S; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium., Lammens L; Preclinical Sciences & Translational Safety, Janssen Pharmaceutica NV, Beerse, Belgium., Pritchard DM; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Publikováno v:
Archives of toxicology [Arch Toxicol] 2023 Jan; Vol. 97 (1), pp. 235-254. Date of Electronic Publication: 2022 Oct 06.
Autor:
Negedu MN; Departments of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 3GE, UK., Duckworth CA; Departments of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 3GE, UK., Yu LG; Departments of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 3GE, UK.
Publikováno v:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 25; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 25.