Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Duck‐Yeon Lee"'
Autor:
David A. Nyenhuis, Susan Watanabe, Rebecca Bernstein, Rolf E. Swenson, Natarajan Raju, Venkata R. Sabbasani, Chandrasekhar Mushti, Duck‐Yeon Lee, Carol Carter, Nico Tjandra
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Here, an in vitro characterization of a family of prazole derivatives that covalently bind to the C73 site on Tsg101 and assay their ability to inhibit viral particle production is presented. Structurally, increased steric bulk on the 4‐py
Externí odkaz:
https://doaj.org/article/666403f4ef1f49f2bc0f62d5ed9b2a67
Autor:
Nicholas J. MacDonald, Kavita Singh, Karine Reiter, Vu Nguyen, Richard Shimp, Apostolos G. Gittis, Beth Chen, Martin Burkhardt, Baoshan Zhang, Zhixiong Wang, Raul Herrera, Mackenzie Moler, Duck-Yeon Lee, Sachy Orr-Gonzalez, Jessica Herrod, Lynn E. Lambert, Kelly M. Rausch, Olga Muratova, David S. Jones, Yimin Wu, Albert J. Jin, David N. Garboczi, Patrick E. Duffy, David L. Narum
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Development of a malaria vaccine that blocks transmission of different parasite stages to humans and mosquitoes is considered critical for elimination efforts. A vaccine using Pfs25, a protein on the surface of zygotes and ookinetes, is unde
Externí odkaz:
https://doaj.org/article/744dd43cb85546b1a8f8ee76086ef8c5
Autor:
Hiroko Ishiwata-Endo, Jiro Kato, Sachiko Yamashita, Chanbora Chea, Kazushige Koike, Duck-Yeon Lee, Joel Moss
Publikováno v:
Cells, Vol 11, Iss 23, p 3853 (2022)
The ARH family of ADP-ribose-acceptor hydrolases consists of three 39-kDa members (ARH1-3), with similarities in amino acid sequence. ARH1 was identified based on its ability to cleave ADP-ribosyl-arginine synthesized by cholera toxin. Mammalian ADP-
Externí odkaz:
https://doaj.org/article/cf809d604511402aa66bc4e2a37fbf11
Autor:
Hyeog Kang, Shinichi Oka, Duck-Yeon Lee, Junhong Park, Angel M. Aponte, Young-Sang Jung, Jacob Bitterman, Peiyong Zhai, Yi He, Hamed Kooshapur, Rodolfo Ghirlando, Nico Tjandra, Sean B. Lee, Myung K. Kim, Junichi Sadoshima, Jay H. Chung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The deacetylase Sirt1, known to regulate many cellular functions, can be activated by energy deprivation, however the mechanism is unclear. Here, the authors show that ATP inhibits Sirt1 by binding to the C-terminal domain, and energy deprivation der
Externí odkaz:
https://doaj.org/article/b6335290698541848579c1e330cc3914
Autor:
Michael J Daly, Elena K Gaidamakova, Vera Y Matrosova, Juliann G Kiang, Risaku Fukumoto, Duck-Yeon Lee, Nancy B Wehr, Gabriela A Viteri, Barbara S Berlett, Rodney L Levine
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12570 (2010)
For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance, manganese accumulation, and protein protection. We show that ult
Externí odkaz:
https://doaj.org/article/1c254163d01c4fb49c698ee02e183923
Autor:
Yi Liu, Zhe Chen, Zong-Heng Wang, Katherine M. Delaney, Juanjie Tang, Mehdi Pirooznia, Duck-Yeon Lee, Ilker Tunc, Yuesheng Li, Hong Xu
Publikováno v:
Nature Cell Biology. 24:757-765
Mitochondrial DNA (mtDNA) replication and transcription are of paramount importance to cellular energy metabolism. Mitochondrial RNA polymerase is thought to be the primase for mtDNA replication. However, it is unclear how this enzyme, which normally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd5a191b16132f5bdceede67bbe3246
https://doi.org/10.1038/s41556-022-00887-y
https://doi.org/10.1038/s41556-022-00887-y
Macrodomain Mac1 of SARS-CoV-2 Nonstructural Protein 3 Hydrolyzes Diverse ADP-ribosylated Substrates
Publikováno v:
bioRxiv
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for a global pandemic that resulted in more than 6-million deaths worldwide. The virus encodes several non-structural proteins (Nsps) that contain elements capable of disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b2bb543fb7d887de03b2594a743a65
https://europepmc.org/articles/PMC10028740/
https://europepmc.org/articles/PMC10028740/
Autor:
Nico Tjandra, Christopher K. E. Bleck, Duck-Yeon Lee, Yi He, David W. Kastner, Sabrina Johnson, Daniel L. Morris, Marie-Paule Strub
Publikováno v:
J Biol Chem
The mitochondrial, or intrinsic, apoptosis pathway is regulated mainly by members of the B-cell lymphoma 2 (BCL-2) protein family. BCL-2–associated X apoptosis regulator (BAX) plays a pivotal role in the initiation of mitochondria-mediated apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4c983b757437c7c615ece4c89188ec
https://doi.org/10.1074/jbc.ra119.011297
https://doi.org/10.1074/jbc.ra119.011297
Publikováno v:
Hepatology
BACKGROUND AND AIMS The regenerative capacity of the liver plays a protective role against hepatotoxins and impaired regeneration exacerbates liver dysfunction in nonalcoholic fatty liver disease (NAFLD). Mitochondrial bioenergetic and -synthetic fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7294d3a282794d9d32e8fe9ca532ca80
https://doi.org/10.1002/hep.30876
https://doi.org/10.1002/hep.30876
Autor:
Duck-Yeon Lee, Alessio Andreoni, Jay R. Knutson, Yingfan Zhang, Brian Glancy, T. Bradley Willingham
Publikováno v:
J Physiol
Key points We developed a novel metabolic imaging approach that provides direct measures of the rate of mitochondrial energy conversion with single-cell and subcellular resolution by evaluating NADH autofluorescence kinetics during the mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b375d620c21058c2f3b0f489bb69c6da
https://doi.org/10.1113/jp278611
https://doi.org/10.1113/jp278611