Analysis of polymorphism at site -174 G/C of interleukin-6 promoter region in multiple myeloma

Autor: Duch, C.R., Figueiredo, M.S., Ribas, C., Almeida, M.S.S., Colleoni, G.W.B., Bordin, J.O.

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 40, Iss 2, Pp 265-267 (2007)
Brazilian Journal of Medical and Biological Research, Volume: 40, Issue: 2, Pages: 265-267, Published: 07 JAN 2007

It is well established that interleukin-6 (IL-6) is an essential growth factor for multiple myeloma (MM) and patients with increased IL-6 levels have a poor prognosis. In healthy subjects, the presence of the C allele at a polymorphic site (-174 G/C)

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200014

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