Is tumour sequencing effective for the identification of germline BRCA1/2 pathogenic variant carriers?

Autor: Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Capone I; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Duca M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Vingiani A; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy., Piccolo A; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Agnelli L; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Tamborini E; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Perrone F; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Peissel B; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Lorenzini D; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy., Damian S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Vernieri C; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; IFOM ETS, The AIRC Institute of Molecular Oncology, Milano, Italy., Bianchi GV; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Mantiero M; Department of Gynecologic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Ducceschi M; Department of Gynecologic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Polignano M; Department of Gynecologic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Niger M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Nichetti F; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany., Proto C; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Brambilla M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Colombo E; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Stellato M; Genitourinary Medical Oncology, Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Roma, Italy., Conca E; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Busico A; Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

Publikováno v: Tumori [Tumori] 2024 Sep 23, pp. 3008916241280127. Date of Electronic Publication: 2024 Sep 23.

Bridging borders with care: a journey in providing oncology treatment to foreign women at a tertiary center in Italy.

Autor: Mantiero M; Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy mara.mantiero@istitutotumori.mi.it., Bini M; Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy., Polignano M; Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy., Raspagliesi F; Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy., Ducceschi M; Department of Gynecologic Oncology, IRCCS National Cancer Institute, Milan, Italy.

Publikováno v: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2024 Jul 01; Vol. 34 (7), pp. 1102. Date of Electronic Publication: 2024 Jul 01.

Explicit Exactly Energy-conserving Methods for Hamiltonian Systems

Autor: Bilbao S., Ducceschi M., Zama F.

Publikováno v: Bilbao, S, Ducceschi, M & Zama, F 2023, ' Explicit exactly energy-conserving methods for Hamiltonian systems ', Journal of Computational Physics, vol. 472, 111697 . https://doi.org/10.1016/j.jcp.2022.111697

For Hamiltonian systems, simulation algorithms that exactly conserve numerical energy or pseudo-energy have seen extensive investigation. Most available methods either require the iterative solution of nonlinear algebraic equations at each time step,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d8ffd68c8e41451447982a1b155347
http://arxiv.org/abs/2206.12391

A Ten-Year Real-Life Experience with Pazopanib in Uterine Leyomiosarcoma in Two High-Specialized Centers in Italy: Effectiveness and Safety.

Autor: Mantiero M; Department of Gynecologic Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Bini M; Department of Medical Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Polignano M; Department of Gynecologic Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Porcu L; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Sanfilippo R; Department of Medical Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Fabbroni C; Department of Medical Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Parma G; Gynecologic Oncology Division, European Institute of Oncology, Via Giuseppe Ripamonti, 435, 20141 Milan, Italy., Lapresa M; Gynecologic Oncology Division, European Institute of Oncology, Via Giuseppe Ripamonti, 435, 20141 Milan, Italy., Calidona C; Gynecologic Oncology Division, European Institute of Oncology, Via Giuseppe Ripamonti, 435, 20141 Milan, Italy.; Department of Obstetrics and Gynecology, AOUI Verona, University of Verona, Piazzale Aristide Stefani 1, 37126 Verona, Italy., Silvestri C; Department of Medical Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Franza A; Department of Medical Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Raspagliesi F; Department of Gynecologic Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy., Colombo N; Gynecologic Oncology Division, European Institute of Oncology, Via Giuseppe Ripamonti, 435, 20141 Milan, Italy.; University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, 20126 Milan, Italy., Ducceschi M; Department of Gynecologic Oncology, National Cancer Institute of Milan, Via Venezian 1, 20133 Milan, Italy.

Publikováno v: Cancers [Cancers (Basel)] 2023 Dec 30; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 30.

The Revolution of Immunotherapy in Gynecological Cancers: The Lazarus Effect in Endometrial Cancer.

Autor: Ducceschi M; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Polignano M; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Bini M; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Lopez S; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Conca E; Department of Innovation Diagnostics, Laboratory of Molecular Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Tamborini E; Department of Innovation Diagnostics, Laboratory of Molecular Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Perrone F; Department of Innovation Diagnostics, Laboratory of Molecular Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Carlo Stella G; Department of Hematology, Oncology, and Molecular Medicine, Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy., Petrella MC; Oncologia Medica Ginecologica, Azienda Ospedaliera Universitaria Careggi, 50134 Firenze, Italy., Carciotto R; Oncologia Medica, Ospedale Maria Paternò Arezzo, 97100 Ragusa, Italy., Artioli G; Oncologia Medica, Ospedale Cà Foncello, 31100 Treviso, Italy., Maffeis V; Anatomia Patologica, Ospedale Cà Foncello, 31100 Treviso, Italy., Sartor L; Oncologia Medica, Ospedale Camposampiero e Cittadella (Padova) ULSS 6, 35012 Euganea, Italy., Raspagliesi F; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy., Mantiero M; Gynecological Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.

Publikováno v: Journal of clinical medicine [J Clin Med] 2023 Aug 25; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 25.