Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Duc-hiep Bach"'
Autor:
Huan Liu, Jin He, Rozita Bagheri-Yarmand, Zongwei Li, Rui Liu, Zhiming Wang, Duc-hiep Bach, Yung-hsing Huang, Pei Lin, Theresa A. Guise, Robert F. Gagel, Jing Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Osteocytes play an important role in the development and progression of tumour-associated bone disease. Here the authors report an interaction between malignant plasma cells and osteocytes in multiple myeloma and show that the osteocyte-expressed maj
Externí odkaz:
https://doaj.org/article/2140f5fa12b140ee994c3e4c763ccd45
Autor:
Zhiming Wang, Jin He, Duc-hiep Bach, Yung-hsing Huang, Zongwei Li, Huan Liu, Pei Lin, Jing Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Therapeutic resistance occurs in most patients with multiple myeloma (MM). One of the key mechanisms for MM drug resistance comes from the interaction between MM cells and adipocytes that inhibits drug-induced apoptosis in MM cell
Externí odkaz:
https://doaj.org/article/f2c2d4d367bb4cd99cd5af8fdd1eb41f
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 118-129 (2019)
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed continuous loops. High-throughput sequencing and
Externí odkaz:
https://doaj.org/article/5a04ea2720f04befa7876119227bae8c
Autor:
Duc-Hiep Bach, Thi-Thu-Trang Luu, Donghwa Kim, Yong Jin An, Sunghyouk Park, Hyen Joo Park, Sang Kook Lee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 817-828 (2018)
Lung cancer is the leading cause of cancer-associated deaths worldwide. In particular, non-small-cell lung cancer (NSCLC) cells harboring epidermal growth factor receptor (EGFR) mutations are associated with resistance development of EGFR tyrosine ki
Externí odkaz:
https://doaj.org/article/a80e2deec0c2451b9af9ecf9b1dc128a
Autor:
Duc-Hiep Bach, Donghwa Kim, Song Yi Bae, Won Kyung Kim, Ji-Young Hong, Hye-Jung Lee, Nirmal Rajasekaran, Soonbum Kwon, Yanhua Fan, Thi-Thu-Trang Luu, Young Kee Shin, Jeeyeon Lee, Sang Kook Lee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 455-467 (2018)
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are used clinically as target therapies for lung cancer patients, but the occurrence of acquired drug resistance limits their efficacy. Nicotinamide N-methyltransferase (NNMT), a
Externí odkaz:
https://doaj.org/article/2804ca286597425e906de0ef1a595b55
Publikováno v:
Molecular Therapy: Oncolytics, Vol 8, Iss , Pp 1-13 (2018)
Bone morphogenetic proteins (BMPs) are a diverse class of molecules with over 20 growth factor proteins that belong to the transforming growth factor-β (TGF-β) family and are highly associated with bone formation and disease development. Aberrant e
Externí odkaz:
https://doaj.org/article/b36a628efaa54b159f2d60925e65679a
Publikováno v:
Marine Drugs, Vol 13, Iss 11, Pp 6962-6976 (2015)
Hypoxia inducible factor-1α (HIF-1α) is an essential regulator of the cellular response to low oxygen concentrations, activating a broad range of genes that provide adaptive responses to oxygen deprivation. HIF-1α is overexpressed in various cance
Externí odkaz:
https://doaj.org/article/df1ce50be01446b9a440d0ceccb6b21c
Autor:
Emine Bayraktar, Sunila Pradeep, Mark Seungwook Kim, Anil K. Sood, Duc-Hiep Bach, Lingegowda S. Mangala, Hyun Jin Choi, Cristina Ivan, Min Soon Cho, Elaine Stur, Cristian Rodriguez-Aguayo, Kyunghee Noh, Gabriel Lopez-Berestein, Santosh K. Dasari, Sherry Y. Wu
Publikováno v:
Oncogene
Paxillin (PXN), a key component of the focal adhesion complex, has been associated with cancer progression, but the underlying mechanisms are poorly understood. The purpose of this study was to elucidate mechanisms by which PXN affects cancer growth
Publikováno v:
Cancer Res
Chromosomal instability (CIN) is one of the major forms of genomic instability in various human cancers and is recognized as a common hallmark of tumorigenesis and heterogeneity. However, some malignant tumors show a paucity of chromosomal alteration
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 118-129 (2019)
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 118-129 (2019)
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed continuous loops. High-throughput sequencing and