Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Dubnovitsky, A"'
Autor:
Lars Rönnblom, Vivianne Malmstrom, Linda Mathsson-Alm, Alexandra Circiumaru, Karine Chemin, Aase Hensvold, Bruno Raposo, Anatoly Dubnovitsky, William W Kwok, Sara Turcinov, Ravi Kumar Sharma, Charlotte De Vries, Christina Gerstner
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Objectives The aim of this study was to combine deep T cell phenotyping with assessment of citrulline-reactive CD4+T cells in the pre-rheumatoid arthritis (RA) phase.Methods 20 anti-CCP2 positive individuals (HLA-DRB1*04:01) presenting musculoskeleta
Externí odkaz:
https://doaj.org/article/277fa97930754a9082fc32bc96040007
Akademický článek
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Autor:
Ravi K. Sharma, Sanjay V. Boddul, Niyaz Yoosuf, Sara Turcinov, Anatoly Dubnovitsky, Genadiy Kozhukh, Fredrik Wermeling, William W. Kwok, Lars Klareskog, Vivianne Malmström
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract We aimed to search for common features in the autoreactive T cell receptor (TCR) repertoire in patients with rheumatoid arthritis (RA), focusing on the newly identified candidate antigen citrullinated Tenascin C (cit-TNC). Mononuclear cells
Externí odkaz:
https://doaj.org/article/14d145fadcf44f8dbefb370495f5fe23
Autor:
Boddul, Sanjaykumar V., Sharma, Ravi Kumar, Dubnovitsky, Anatoly, Raposo, Bruno, Gerstner, Christina, Shen, Yunbing, Iyer, Vaishnavi Srinivasan, Kasza, Zsolt, Kwok, William W., Winkler, Aaron R., Klareskog, Lars, Malmström, Vivianne, Bettini, Maria, Wermeling, Fredrik
Publikováno v:
In Journal of Translational Autoimmunity 2021 4
Autor:
Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik
Publikováno v:
In Computational and Structural Biotechnology Journal 2021 19:5360-5370
Autor:
Yunbing Shen, Long Jiang, Vaishnavi Srinivasan Iyer, Bruno Raposo, Anatoly Dubnovitsky, Sanjaykumar V. Boddul, Zsolt Kasza, Fredrik Wermeling
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5360-5370 (2021)
CRISPR/Cas9 can be used as an experimental tool to inactivate genes in cells. However, a CRISPR-targeted cell population will not show a uniform genotype of the targeted gene. Instead, a mix of genotypes is generated - from wild type to different for
Externí odkaz:
https://doaj.org/article/7ef9e66cdc654f80b5bdd9d389d86c63
Autor:
Christina Gerstner, Sara Turcinov, Aase H. Hensvold, Karine Chemin, Hannes Uchtenhagen, Tamara H. Ramwadhdoebe, Anatoly Dubnovitsky, Genadiy Kozhukh, Lars Rönnblom, William W. Kwok, Adnane Achour, Anca I. Catrina, Lisa G. M. van Baarsen, Vivianne Malmström
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background HLA class II tetramers can be used for ex vivo enumeration and phenotypic characterisation of antigen-specific CD4+ T cells. They are increasingly applied in settings like allergy, vaccination and autoimmune diseases. Rheumatoid a
Externí odkaz:
https://doaj.org/article/f8223eae0acb4a2482098dfe1e7f57f9
Autor:
Pieper, Jennifer, Dubnovitsky, Anatoly, Gerstner, Christina, James, Eddie A., Rieck, Mary, Kozhukh, Genadiy, Tandre, Karolina, Pellegrino, Sara, Gebe, John A., Rönnblom, Lars, Sandalova, Tatyana, Kwok, William W., Klareskog, Lars, Buckner, Jane H., Achour, Adnane, Malmström, Vivianne
Publikováno v:
In Journal of Autoimmunity August 2018 92:47-56
Autor:
Sanjaykumar V. Boddul, Ravi Kumar Sharma, Anatoly Dubnovitsky, Bruno Raposo, Christina Gerstner, Yunbing Shen, Vaishnavi Srinivasan Iyer, Zsolt Kasza, William W. Kwok, Aaron R. Winkler, Lars Klareskog, Vivianne Malmström, Maria Bettini, Fredrik Wermeling
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100087- (2021)
Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as
Externí odkaz:
https://doaj.org/article/2b65dc3e4d654d289c3343c4f2d8dba0
Autor:
Miranda Houtman, Anna Dzebisashvili, Anatoly Dubnovitsky, Genadiy Kozhukh, Lars Rönnblom, Lars Klareskog, Vivianne Malmström, Leonid Padyukov
Publikováno v:
Molecular Immunology. 152:106-110
Allelic variants of HLA-DRB1 have been associated with a variety of autoimmune and infectious diseases. Although the precise molecular mechanisms by which HLA-DRB1 alleles predispose to a particular disease are currently unclear, it has been shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8956cca3c9446581e51c19973695a48
https://doi.org/10.1016/j.molimm.2022.10.008
https://doi.org/10.1016/j.molimm.2022.10.008