Zobrazeno 1 - 10 of 381 pro vyhledávání: '"Dubarry, N."'
1
Akademický článek
In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens.
Autor: Kany AM; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany., Fries F; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Department of Pharmacy, Saarland University, Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany., Seyfert CE; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany., Porten C; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Department of Pharmacy, Saarland University, Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany., Deckarm S; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Department of Pharmacy, Saarland University, Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany., Chacón Ortiz M; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany., Dubarry N; Evotec, Lyon 69007, France., Vaddi S; Evotec, Alderly Park SK10 4TG, United Kingdom., Große M; Helmholtz Centre for Infection Research (HZI), Department Microbial Drugs, Braunschweig 38124, Germany., Bernecker S; Helmholtz Centre for Infection Research (HZI), Department Microbial Drugs, Braunschweig 38124, Germany., Sandargo B; Helmholtz Centre for Infection Research (HZI), Department Microbial Drugs, Braunschweig 38124, Germany., Müller AV; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Department of Pharmacy, Saarland University, Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany., Bacqué E; Evotec, Marcy L'Etoile 69280, France., Stadler M; Helmholtz Centre for Infection Research (HZI), Department Microbial Drugs, Braunschweig 38124, Germany.; Institute of Microbiology, Technische Universität Braunschweig, Braunschweig 38106, Germany., Herrmann J; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany., Müller R; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken 66123, Germany.; Department of Pharmacy, Saarland University, Saarbrücken 66123, Germany.; Deutsches Zentrum für Infektionsforschung (DZIF) e.V., Braunschweig 38124, Germany.; Helmholtz International Lab for Anti-infectives, Saarbrücken 66123, Germany.
Publikováno v: ACS infectious diseases [ACS Infect Dis] 2024 Dec 13; Vol. 10 (12), pp. 4337-4346. Date of Electronic Publication: 2024 Nov 20.
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2
Akademický článek
Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs).
Autor: Couturier C; Evotec, 1541, Avenue Marcel Mérieux, 69280, Marcy L'Etoile, France. Electronic address: cedric.couturier@evotec.com., Ronzon Q; Evotec, 1541, Avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Lattanzi G; Evotec-Aptuit (Verona) Srl, Via Alessandro Fleming 4, 37135, Verona, Italy., Lingard I; Evotec-Aptuit (Verona) Srl, Via Alessandro Fleming 4, 37135, Verona, Italy., Coyne S; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Cazals V; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Dubarry N; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Yvon S; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Leroi-Geissler C; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Gracia OR; Evotec, 195, Route D'Espagne, 31100, Toulouse, France., Teague J; Evotec, No. 23F, Mereside, Alderley Park, Cheshire, SK10 4TG, United Kingdom., Sordello S; Evotec, 195, Route D'Espagne, 31100, Toulouse, France., Corbett D; Evotec, No. 23F, Mereside, Alderley Park, Cheshire, SK10 4TG, United Kingdom., Bauch C; Evotec-Cyprotex, No. 24, Mereside, Alderley Park, Cheshire, SK10 4TG, United Kingdom., Monlong C; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Payne L; Evotec, No. 23F, Mereside, Alderley Park, Cheshire, SK10 4TG, United Kingdom., Taillier T; Evotec, 195, Route D'Espagne, 31100, Toulouse, France., Fuchs H; Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstraße 7, 38124, Braunschweig, Germany., Broenstrup M; Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstraße 7, 38124, Braunschweig, Germany., Harrison PH; Division of Structural Biology, Wellcome Trust Centre of Human Genomics, 7 Roosevelt Drive, Oxford, OX3 7BN, United Kingdom., Moynié L; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, OX11 0QS, United Kingdom., Lakshminarayanan A; Division of Structural Biology, Wellcome Trust Centre of Human Genomics, 7 Roosevelt Drive, Oxford, OX3 7BN, United Kingdom., Gianga TM; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot, OX11 0DE, United Kingdom., Hussain R; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot, OX11 0DE, United Kingdom., Naismith JH; Division of Structural Biology, Wellcome Trust Centre of Human Genomics, 7 Roosevelt Drive, Oxford, OX3 7BN, United Kingdom; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, OX11 0QS, United Kingdom., Mourez M; Evotec, 40 Avenue Tony Garnier, 69007, Lyon, France., Bacqué E; Evotec, 1541, Avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Björkling F; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, DK-2100, Denmark., Sabuco JF; Evotec, 1541, Avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Franzyk H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 162, DK-2100, Denmark.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 05; Vol. 265, pp. 116097. Date of Electronic Publication: 2023 Dec 23.
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3
Akademický článek
Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin.
Autor: Renard S; Evotec, 40 Avenue Tony Garnier, Lyon 69007, France., Versluys S; Evotec, 195, Route d'Espagne, Toulouse 31100, France., Taillier T; Evotec, 1541, Avenue Marcel Mérieux, Marcy L'Etoile 69280, France., Dubarry N; Evotec, 40 Avenue Tony Garnier, Lyon 69007, France., Leroi-Geissler C; Evotec, 40 Avenue Tony Garnier, Lyon 69007, France., Rey A; Evotec, 1541, Avenue Marcel Mérieux, Marcy L'Etoile 69280, France., Cornaire E; Evotec, 1541, Avenue Marcel Mérieux, Marcy L'Etoile 69280, France., Sordello S; Evotec, 195, Route d'Espagne, Toulouse 31100, France., Carry JB; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Angouillant-Boniface O; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Gouyon T; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Thompson F; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Lebourg G; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Certal V; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Balazs L; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Arranz E; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Doerflinger G; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Bretin F; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Gervat V; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Brohan E; Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine 94403, France., Kraft V; Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main 65926, Germany., Boulenc X; Evotec, 40 Avenue Tony Garnier, Lyon 69007, France., Ducelier C; Sanofi, 1 Avenue Pierre Brossolette, Chilly-Mazarin 91385, France., Bacqué E; Evotec, 1541, Avenue Marcel Mérieux, Marcy L'Etoile 69280, France., Couturier C; Evotec, 1541, Avenue Marcel Mérieux, Marcy L'Etoile 69280, France.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Dec 28; Vol. 66 (24), pp. 16869-16887. Date of Electronic Publication: 2023 Dec 13.
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4
Akademický článek
Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin.
Autor: Couturier C; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Groß S; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., von Tesmar A; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Hoffmann J; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Deckarm S; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Fievet A; Evotec, 40 avenue Tony Garnier, 69007, Lyon, France., Dubarry N; Evotec, 40 avenue Tony Garnier, 69007, Lyon, France., Taillier T; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Pöverlein C; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Stump H; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Kurz M; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Toti L; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Haag Richter S; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Schummer D; Technische Hochschule Mittelhessen, Wiesenstraße 14, 35390, Gießen, Germany., Sizun P; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Hoffmann M; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Prasad Awal R; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Zaburannyi N; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Harmrolfs K; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Wink J; Mikrobielle Stammsammlung, Helmholtz Centre for Infection Research (HZI), Inhoffenstraße 7, 38124, Braunschweig, Germany., Lessoud E; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Vermat T; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Cazals V; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Silve S; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Bauer A; Sanofi, 13, Quai Jules Guesde, 94400, Vitry-sur-Seine, France., Mourez M; Ecole d'Ingénieurs de Purpan, 75 voie du Toec, BP57611, 31076, Toulouse, France., Fraisse L; Drug for Neglected Diseases Initiative, Chemin Camille-Vidart 15, 1202, Geneva, Switzerland., Leroi-Geissler C; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Rey A; Charles River Laboratories, 327 impasse du domaine rozier, 69210, Saint-Germain-Nuelles, France., Versluys S; Evotec, 195, route d'Espagne, 31000, Toulouse, France., Bacqué E; Evotec, 1541, avenue Marcel Mérieux, 69280, Marcy L'Etoile, France., Müller R; Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Renard S; Evotec, 40 avenue Tony Garnier, 69007, Lyon, France.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Dec 19; Vol. 61 (51), pp. e202210747. Date of Electronic Publication: 2022 Nov 21.
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5
In vivo imagining of the segregation of the 2 chromosomes and the cell division proteins of Rhodobacter sphaeroides reveals an unexpected role for MipZ
Autor: Dubarry, N, Willis, C, Bell, G, Lesterlin, C, Armitage, J
Coordinating chromosome duplication and segregation with cell division is clearly critical for bacterial species. This precise choreography required is even more complex in species with more than one chromosome. The alpha subgroup of bacteria contain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0bb5ff9d12dc046cdc599174832ab227
https://doi.org/10.1128/mbio.02515-18
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6
Multiple regions along the Escherichia coli FtsK protein are implicated in cell division
Autor: Dubarry, N, Possoz, C, Barre, FX
Escherichia coli FtsK is a large 1329 aa integral membrane protein, which links cell division and chromosome segregation through the respective activities of its 200 aa amino-terminal domain, FtsK(N), and its 500 aa carboxy-terminal domain, FtsK(C).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::24ce73070252def97a359d9dacde23d4
https://ora.ox.ac.uk/objects/uuid:2c13d92c-569d-41be-b61b-21fef28ef352
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7
RcsCDB His-Asp phosphorelay system negatively regulates the flhDC operon in Escherichia coli
Autor: Francez-Charlot, A, Laugel, B, Van Gemert, A, Dubarry, N, Wiorowski, F, Castanié-Cornet, MP, Gutierrez, C, Cam, K
The genes involved in flagellum synthesis, motility and chemotaxis in Escherichia coli are expressed in a hierarchical fashion. At the top of the hierarchy lies the master regulator FlhDC, required for the expression of the whole set of genes. The op
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::82d086077b7dadfd3ba3c04df285a0dc
https://ora.ox.ac.uk/objects/uuid:71d0efce-099f-474d-95d9-3cd458e5e4f2
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8
Akademický článek
Deep phosphoproteomics of Klebsiella pneumoniae reveals HipA-mediated tolerance to ciprofloxacin.
Autor: Nashier, Payal1 (AUTHOR), Samp, Isabell2 (AUTHOR), Adler, Marvin2 (AUTHOR), Ebner, Fiona2 (AUTHOR), Lê, Lisa Thai2 (AUTHOR), Göppel, Marc2 (AUTHOR), Jers, Carsten3 (AUTHOR), Mijakovic, Ivan3,4 (AUTHOR), Schwarz, Sandra2 (AUTHOR) sandra.schwarz@med.uni-tuebingen.de, Macek, Boris1 (AUTHOR) boris.macek@uni-tuebingen.de
Publikováno v: PLoS Pathogens. 12/12/2024, Vol. 20 Issue 12, p1-23. 23p.
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9
Akademický článek
Harnessing Gram‐negative bacteria for novel anti‐Gram‐negative antibiotics.
Autor: Birkelbach, Joy1,2 (AUTHOR), Seyfert, Carsten E.1,2 (AUTHOR), Walesch, Sebastian1,2 (AUTHOR), Müller, Rolf1,2 (AUTHOR) rolf.mueller@helmholtz‐hips.de
Publikováno v: Microbial Biotechnology. Nov2024, Vol. 17 Issue 11, p1-10. 10p.
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