Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dub, deubiquitinase"'
Autor:
Chenxi Zhao, Hong Zhu, Xiaoyang Dai, Weihua Wang, Meijia Qian, Xin Dong, Nengming Lin, Jiao Wang, Jiabin Lu, Bo Yang, Qiaojun He, Xiaowu Dong, Fangjie Yan, Tao Yuan, Bo Zhang, Jiamin Du, Ruilin Wu
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 4008-4019 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 4008-4019 (2021)
Cholangiocarcinoma (CCA) has emerged as an intractable cancer with scanty therapeutic regimens. The aberrant activation of Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are reported to be common in CCA pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626f01f78adbe5f9659fdd17326d365a
http://europepmc.org/articles/PMC8727894
http://europepmc.org/articles/PMC8727894
Autor:
Zhenyu Luo, Cuifu Yu, Renjie Chai, Hongbiao Huang, Yangshuo Jin, Ningning Liu, Xiaohong Xia, Tumei Hu, Bijun Du, Jielei Gu, Qiong Xu, Shiming Liu, Wenchao Ou, Xiaolin Liu
Publikováno v:
The Journal of Biological Chemistry
The underlying mechanism of neointima formation remains unclear. Ubiquitin-specific peptidase 10 (USP10) is a deubiquitinase that plays a major role in cancer development and progression. However, the function of USP10 in arterial restenosis is unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3a7a44021dfe977b403f744520a584
http://europepmc.org/articles/PMC8524199
http://europepmc.org/articles/PMC8524199
Autor:
Yuanming He, Zubin Zhang, Yuanying Zeng, Xinliang Mao, Jun Zhao, Chenyu Mao, Hui Zheng, Shuoyi Jiang, Biyin Cao
Publikováno v:
The Journal of Biological Chemistry
The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) protein is a key player in tumorigenesis of non–small cell lung cancer (NSCLC) and was recently found to be inactivated by tripartite motif containing 25 (TRIM25)–mediated K63-lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fe00339daaaaebc6502219d884bbcd
http://europepmc.org/articles/PMC8429974
http://europepmc.org/articles/PMC8429974
Publikováno v:
The Journal of Biological Chemistry
Marafiviruses are capable of persistent infection in a range of plants that have importance to the agriculture and biofuel industries. Although the genomes of a few of these viruses have been studied in-depth, the composition and processing of the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cc6480ae05ba1150d64902fd7fd986
https://pubmed.ncbi.nlm.nih.gov/34265303
https://pubmed.ncbi.nlm.nih.gov/34265303
Autor:
Adam Pennycuick, Neelam Kumar, Xidan Zhang, Mary Falzon, Krishna K. Kolluri, Ersilia Nigro, Yuki Ishii, Doraid Alrifai, Khalid Shah, Elaine Borg, Sam M. Janes
Publikováno v:
The Journal of Biological Chemistry
Malignant pleural mesothelioma (MPM) is a rare, aggressive, and incurable cancer arising from the mesothelial lining of the pleura, with few available treatment options. We recently reported that loss of function of the nuclear deubiquitinase BRCA1-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b29ae2da35ab58c009cd489419063c2
https://pubmed.ncbi.nlm.nih.gov/34597666
https://pubmed.ncbi.nlm.nih.gov/34597666
Autor:
Georgina Berridge, Janic Le Pen, Juliusz Mieszczanek, Lee D. Harris, Benedikt M. Kessler, Natalie Vaughan, Simon J. Davis, Mariann Bienz, Julien D.F. Licchesi, Nico Scholz
Publikováno v:
Harris, L D, Le Pen, J, Scholz, N, Mieszczanek, J, Vaughan, N, Davis, S, Berridge, G, Kessler, B, Bienz, M & Licchesi, J 2021, ' The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1 ', Journal of Biological Chemistry, vol. 296, no. 1, 100246 . https://doi.org/10.1074/jbc.RA120.015162
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Ubiquitin is a versatile post-translational modification which is covalently attached to protein targets either as a single moiety or as a ubiquitin chain. In contrast to K48 and K63- linked chains which have been extensively studied, the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bf631083b388fa81a2e5c8a620dc01
https://purehost.bath.ac.uk/ws/files/217198202/J._Biol._Chem._2020_Harris_jbc.RA120.015162.pdf
https://purehost.bath.ac.uk/ws/files/217198202/J._Biol._Chem._2020_Harris_jbc.RA120.015162.pdf
Publikováno v:
Molecular & Cellular Proteomics : MCP
Mol Cell Proteomics
Mol Cell Proteomics
Ubiquitination is a posttranslational protein modification that has been shown to have a range of effects, including regulation of protein function, interaction, localization, and degradation. We have previously shown that the muscle-specific ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88a5086222dd382a409e9eec910c431
http://europepmc.org/articles/PMC8042406
http://europepmc.org/articles/PMC8042406
Autor:
Nerea Osinalde, Blagoy Blagoev, Irina Kratchmarova, Virginia Sanchez-Quiles, Vyacheslav Akimov
Publikováno v:
Data in Brief, Vol 18, Iss, Pp 1856-1863 (2018)
Data in Brief
Sanchez-Quiles, V, Osinalde, N, Akimov, V, Kratchmarova, I & Blagoev, B 2018, ' Data on mass spectrometry-based proteomics for studying the involvement of CYLD in the ubiquitination events downstream of EGFR activation ', Data in Brief, vol. 18, pp. 1856-1863 . https://doi.org/10.1016/j.dib.2018.04.049
Data in Brief
Sanchez-Quiles, V, Osinalde, N, Akimov, V, Kratchmarova, I & Blagoev, B 2018, ' Data on mass spectrometry-based proteomics for studying the involvement of CYLD in the ubiquitination events downstream of EGFR activation ', Data in Brief, vol. 18, pp. 1856-1863 . https://doi.org/10.1016/j.dib.2018.04.049
The present data article corresponds to the proteomic data of the involvement of Cylindromatosis protein (CYLD) in the ubiquitination signaling initiated by EGF stimulation. CYLD tumor suppressor protein has Lys63-chain deubiquitinase activity that h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88e86b5899b4026b887739f1a86598b
http://www.sciencedirect.com/science/article/pii/S2352340918304001
http://www.sciencedirect.com/science/article/pii/S2352340918304001
Autor:
Chittaranjan Das, Shalini Iyer
Publikováno v:
The Journal of Biological Chemistry
Legionella pneumophila is a facultative intracellular pathogen that uses the Dot/Icm Type IV secretion system (T4SS) to translocate many effectors into its host and establish a safe, replicative lifestyle. The bacteria, once phagocytosed, reside in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80271bfda120e5b85ce17c4c5ceac7c4
https://doi.org/10.1016/j.jbc.2021.101340
https://doi.org/10.1016/j.jbc.2021.101340
Autor:
Justyna Bajdzienko, Andreas Kern, Mila Basic, Alexandra Hertel, Mariana Tellechea, Alexandra Stolz, Florian Bonn, Christian Behl, Anja Bremm
Publikováno v:
The Journal of Biological Chemistry
Autophagy is a major cellular quality control system responsible for the degradation of proteins and organelles in response to stress and damage to maintain homeostasis. Ubiquitination of autophagy-related proteins or regulatory components is importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6aec8482a221b2fc2ecdbdb5981944
https://doi.org/10.1016/j.jbc.2021.101263
https://doi.org/10.1016/j.jbc.2021.101263