Molecular insights into intra-complex signal transmission during stressosome activation

Autor: Algirdas Miksys, Lifei Fu, M. Gregor Madej, Duarte N. Guerreiro, Susann Kaltwasser, Maria Conway, Sema Ejder, Astrid Bruckmann, Jon Marles-Wright, Richard J. Lewis, Conor O’Byrne, Jan Pané-Farré, Christine Ziegler

Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)

Cryo-EM structures of the stress-sensing complex in Listeria innocua reveal conformational changes that initiate the signaling response to environmental stress.

Externí odkaz: https://doaj.org/article/faa9afa773db4d11bf6a756c291707a8

The stressosome is required to transduce low pH signals leading to increased transcription of the amino acid-based acid tolerance mechanisms in Listeria monocytogenes

Autor: Duarte N. Guerreiro, Aoife Boyd, Conor P. O'Byrne

Publikováno v: Access Microbiology. 4

Increasing proton concentration in the environment represents a potentially lethal stress for single-celled microorganisms. To survive in an acidifying environment, the foodborne pathogen Listeria monocytogenes quickly activates the alternative sigma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73c86844077ece5a3dbc595c759a4dc8
https://doi.org/10.1099/acmi.0.000455

Listeria monocytogenes requires the RsbX protein to prevent SigB-activation under non-stressed conditions

Autor: Hasan Tükenmez, Ana H. Oliveira, Duarte N. Guerreiro, Francisco García-del Portillo, Jörgen Johansson, Charlotte Dessaux, Teresa Tiensuu, Conor P. O'Byrne

Publikováno v: Journal of Bacteriology

The survival of microbial cells under changing environmental conditions requires an efficient reprogramming of transcription, often mediated by alternative sigma factors. The Gram-positive human pathogen Listeria monocytogenes senses and responds to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13fd181373e6da5e8679ea407e575b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190844

Evolutionary trade-offs between growth and survival: The delicate balance between reproductive success and longevity in bacteria

Autor: Duarte N. Guerreiro, Florence Abram, Talia Arcari, Conor P. O'Byrne

Publikováno v: Advances in Microbial Physiology ISBN: 9780128246023

All living cells strive to allocate cellular resources in a way that promotes maximal evolutionary fitness. While there are many competing demands for resources the main decision making process centres on whether to proceed with growth and reproducti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f03d2be6ba10fc4077fd600d35b18d0
https://doi.org/10.1016/bs.ampbs.2021.07.002

Mild Stress Conditions during Laboratory Culture Promote the Proliferation of Mutations That Negatively Affect Sigma B Activity in Listeria monocytogenes

Autor: Teresa Tiensuu, Diana Gudynaite, Aoife Boyd, Francisco García-del Portillo, Duarte N. Guerreiro, Jialun Wu, Catarina M. Marinho, Jörgen Johansson, Ana H. Oliveira, Charlotte Dessaux, Conor P. O'Byrne

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2020, 202 (9), ⟨10.1128/jb.00751-19⟩
J Bacteriol
Digital.CSIC. Repositorio Institucional del CSIC
instname

In Listeria monocytogenes, the full details of how stress signals are integrated into the σB regulatory pathway are not yet available. To help shed light on this question, we investigated a collection of transposon mutants that were predicted to hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bffb864f7d03b39ddb7189260b4b2d0