Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Duarte L Martins"'
Autor:
Piergiuseppe Nestola, Duarte L Martins, Cristina Peixoto, Susanne Roederstein, Tobias Schleuss, Paula M Alves, José P B Mota, Manuel J T Carrondo
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115802 (2014)
The purification of virus particles and viral vectors for vaccine and gene therapy applications is gaining increasing importance in order to deliver a fast, efficient, and reliable production process. Ultrafiltration (UF) is a widely employed unit op
Externí odkaz:
https://doaj.org/article/b9968d7423bc44c083981427a051089b
Publikováno v:
New Biotechnology. 55:98-107
A narrow residence time distribution (RTD) is highly desirable for continuous processes where a strict incubation time must be ensured, such as continuous virus inactivation. A narrow RTD also results in faster startup and shut down phases and limits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9810cb0643437d193917a176abd5ace4
https://doi.org/10.1016/j.nbt.2019.10.006
https://doi.org/10.1016/j.nbt.2019.10.006
Autor:
Jure Sencar, Nikolaus Hammerschmidt, Thomas R. Kreil, Alois Jungbauer, Johanna Kindermann, Andreas Flicker, Duarte L. Martins
Publikováno v:
Biotechnology and Bioengineering
Continuous virus inactivation (VI) has received little attention in the efforts to realize fully continuous biomanufacturing in the future. Implementation of continuous VI must assure a specific minimum incubation time, typically 60 min. To guarantee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7ad716973b315309da0a060c68c24e
https://doi.org/10.1002/bit.27292
https://doi.org/10.1002/bit.27292
Autor:
Jure Sencar, Björn Tille, Duarte L. Martins, Alois Jungbauer, Thomas R. Kreil, Nikolaus Hammerschmidt, Johanna Kinderman
Publikováno v:
Biotechnology journal. 14(8)
Continuous virus inactivation (VI) remains one of the missing pieces while the biopharma industry moves toward continuous manufacturing. The challenges of adapting VI to the continuous operation are two-fold: 1) achieving fluid homogeneity and 2) a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8dc44dad0df3a8eef38f0d8a12d53d
https://pubmed.ncbi.nlm.nih.gov/30810288
https://pubmed.ncbi.nlm.nih.gov/30810288