Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Duanwei Liang"'
Autor:
Liangliang Zhang, Duanwei Liang, Changmai Chen, Yuan Wang, Gubu Amu, Jiali Yang, Lijia Yu, Ivan J. Dmochowski, Xinjing Tang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 237-244 (2018)
Circular non-coding RNAs are found to play important roles in biology but are still relatively unexplored as a structural motif for chemically regulating gene function. Here, we investigated whether small interfering RNA (siRNA) with a circular struc
Externí odkaz:
https://doaj.org/article/7b069acb5ffb4ce4841d0debe1a4898d
Publikováno v:
Bioconjugate Chemistry. 31:182-193
Precise detection and effective treatment are crucial to prolong cancer patients' lives. Surface-enhanced Raman scattering (SERS) imaging coupled with photothermal therapy has been considered a precise and effective strategy for cancer theranostics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066c83443e3babe340e17ba17037c082
https://doi.org/10.1021/acs.bioconjchem.0c00022
https://doi.org/10.1021/acs.bioconjchem.0c00022
Publikováno v:
Analytical Chemistry. 91:11045-11054
Early precise diagnosis of cancers is crucial to realize more effective therapeutic interventions with minimal toxic effects. Cancer phenotypes may also alter greatly among patients and within individuals over the therapeutic process. The identificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afaf05fffe560c9826bbda9afee2d219
https://doi.org/10.1021/acs.analchem.9b01382
https://doi.org/10.1021/acs.analchem.9b01382
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2115
We designed and synthesized caged siRNAs with photolabile linker and single cRGD peptide modifications for the photoregulation of gene expression. Photolabile linker and cRGD were inserted at 5' terminus of siRNAs to obtain cRGD-modified caged siRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b0ee231273164e5a2f10b0ae7cb961c
https://pubmed.ncbi.nlm.nih.gov/32006399
https://pubmed.ncbi.nlm.nih.gov/32006399
Publikováno v:
Bioconjugate chemistry. 31(2)
Precise detection and effective treatment are crucial to prolong cancer patients' lives. Surface-enhanced Raman scattering (SERS) imaging coupled with photothermal therapy has been considered a precise and effective strategy for cancer theranostics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6439c68de875e7821829a92b27a617c6
https://pubmed.ncbi.nlm.nih.gov/31940174
https://pubmed.ncbi.nlm.nih.gov/31940174
Publikováno v:
RNA Interference and CRISPR Technologies ISBN: 9781071602898
We designed and synthesized caged siRNAs with photolabile linker and single cRGD peptide modifications for the photoregulation of gene expression. Photolabile linker and cRGD were inserted at 5' terminus of siRNAs to obtain cRGD-modified caged siRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52e044404e0353400bd5e9366aabcd46
https://doi.org/10.1007/978-1-0716-0290-4_8
https://doi.org/10.1007/978-1-0716-0290-4_8
Autor:
Xinjing Tang, Gubu Amu, Liangliang Zhang, Changmai Chen, Jiali Yang, Duanwei Liang, Ivan J. Dmochowski, Lijia Yu, Yuan Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 237-244 (2018)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Circular non-coding RNAs are found to play important roles in biology but are still relatively unexplored as a structural motif for chemically regulating gene function. Here, we investigated whether small interfering RNA (siRNA) with a circular struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbfbe56c8a1d8b3e65e429c355b7e6f
http://www.sciencedirect.com/science/article/pii/S2162253117303062
http://www.sciencedirect.com/science/article/pii/S2162253117303062
Publikováno v:
Biomacromolecules. 17:3153-3161
A series of Vitamin E (vitE)-labeled PEIs (PEI-vitEn) were synthesized and showed excellent complexation ability with plasmid DNA (pDNA). The cellular uptake of PEI-vitEn/pDNA complexes was greatly enhanced with the increase of vitE labeling, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aa3a8fd7d57a36bc83c38d0966af39
https://doi.org/10.1021/acs.biomac.6b00776
https://doi.org/10.1021/acs.biomac.6b00776
Publikováno v:
Analytical Chemistry. 88:9213-9218
Two fluorescent chemosenors, Mito-HS and Lyso-HS, were rationally designed and synthesized with positive charge at physiological conditions. The positive charge showed triple functions as target moieties for subcellular mitochondria and lysosome of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f544af3390815386e8ffecdeafd038
https://doi.org/10.1021/acs.analchem.6b02459
https://doi.org/10.1021/acs.analchem.6b02459
Publikováno v:
Biomacromolecules. 19(7)
RNA interference (RNAi) mediated gene silencing holds significant promise in gene therapy. It is very important to manually regulate the activity of small interference RNAs (siRNAs) in the controllable mode. Here, we designed and synthesized a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142670a9ea266da1f6d9400fc4c86c45
https://pubmed.ncbi.nlm.nih.gov/29727579
https://pubmed.ncbi.nlm.nih.gov/29727579