Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Duane L Pierson"'
Autor:
Aurélie Crabbé, Sheila M Nielsen-Preiss, Christine M Woolley, Jennifer Barrila, Kent Buchanan, James McCracken, Diane O Inglis, Stephen C Searles, Mayra A Nelman-Gonzalez, C Mark Ott, James W Wilson, Duane L Pierson, Heidemarie M Stefanyshyn-Piper, Linda E Hyman, Cheryl A Nickerson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80677 (2013)
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions. Microarray analysis revealed that C. albicans subjecte
Externí odkaz:
https://doaj.org/article/ffdd3ffecb1e4513be68bb69cd7acfc6
Autor:
James W Wilson, C Mark Ott, Laura Quick, Richard Davis, Kerstin Höner zu Bentrup, Aurélie Crabbé, Emily Richter, Shameema Sarker, Jennifer Barrila, Steffen Porwollik, Pui Cheng, Michael McClelland, George Tsaprailis, Timothy Radabaugh, Andrea Hunt, Miti Shah, Mayra Nelman-Gonzalez, Steve Hing, Macarena Parra, Paula Dumars, Kelly Norwood, Ramona Bober, Jennifer Devich, Ashleigh Ruggles, Autumn CdeBaca, Satro Narayan, Joseph Benjamin, Carla Goulart, Mark Rupert, Luke Catella, Michael J Schurr, Kent Buchanan, Lisa Morici, James McCracken, Marc D Porter, Duane L Pierson, Scott M Smith, Max Mergeay, Natalie Leys, Heidemarie M Stefanyshyn-Piper, Dominic Gorie, Cheryl A Nickerson
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3923 (2008)
The spaceflight environment is relevant to conditions encountered by pathogens during the course of infection and induces novel changes in microbial pathogenesis not observed using conventional methods. It is unclear how microbial cells sense spacefl
Externí odkaz:
https://doaj.org/article/08e4f996dc984c28a049418e1d06b4c4
Autor:
Alexander A. Voorhies, C. Mark Ott, Satish Mehta, Duane L. Pierson, Brian E. Crucian, Alan Feiveson, Cherie M. Oubre, Manolito Torralba, Kelvin Moncera, Yun Zhang, Eduardo Zurek, Hernan A. Lorenzi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Abstract Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes and may have a negative impact on astronauts’ health. H
Externí odkaz:
https://doaj.org/article/a5cf7868343a469e881872fed67500f3
Autor:
Madhan R. Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah J. Bruce, C. Mark Ott, Duane L. Pierson, George E. Fox
Publikováno v:
npj Microgravity, Vol 3, Iss 1, Pp 1-9 (2017)
Evolution: Bacteria gain advantageous mutations under simulated microgravity Bacteria grown for an extended period of time under simulated microgravity adopt growth advantages. George Fox and colleagues from the University of Houston, Texas, USA, cul
Externí odkaz:
https://doaj.org/article/00446c7756a24031b3ea4ce32713b3c5
Autor:
Satish K. Mehta, Mark L. Laudenslager, Raymond P. Stowe, Brian E. Crucian, Alan H. Feiveson, Clarence F. Sams, Duane L. Pierson
Publikováno v:
npj Microgravity, Vol 3, Iss 1, Pp 1-8 (2017)
Virus reactivation in long-duration spaceflight Long-duration spaceflight increases the reactivation of latent herpes viruses in astronauts and is accompanied by a rise in stress hormone levels. This study shows that the frequency and viral loads of
Externí odkaz:
https://doaj.org/article/f32947e92776479e9e3b840364e87d36
Autor:
Madhan R. Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah J. Bruce, C. Mark Ott, Duane L. Pierson, George E. Fox
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The long-term response of microbial communities to the microgravity environment of space is not yet fully understood. Of special interest is the possibility that members of these communities may acquire antibiotic resistance. In this study,
Externí odkaz:
https://doaj.org/article/d91d94ba901144bea9787a024c551038
Autor:
Brian E. Crucian, Alexander Choukèr, Richard J. Simpson, Satish Mehta, Gailen Marshall, Scott M. Smith, Sara R. Zwart, Martina Heer, Sergey Ponomarev, Alexandra Whitmire, Jean P. Frippiat, Grace L. Douglas, Hernan Lorenzi, Judith-Irina Buchheim, George Makedonas, Geoffrey S. Ginsburg, C. Mark Ott, Duane L. Pierson, Stephanie S. Krieger, Natalie Baecker, Clarence Sams
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight. It appears certain aspects of adaptive immunity are dysregulated du
Externí odkaz:
https://doaj.org/article/3004e90bcb074975994e73e64239391c
Autor:
Brian Crucian, Austin B. Bigley, Li Li, Katayoun Rezvani, Richard J. Simpson, Satish K. Mehta, Preteesh L. Mylabathula, Mitzi S. Laughlin, Melissa M. Markofski, Duane L. Pierson
Publikováno v:
Acta Astronautica. 174:32-40
Long-duration spaceflight impairs natural killer (NK) cell function, which could compromise immune surveillance in exploration class mission crew. To determine if microgravity can impair NK-cell function, we established a rotary cell culture system t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47fe26447f69d924cceac4809e49e6ed
https://doi.org/10.1016/j.actaastro.2020.03.023
https://doi.org/10.1016/j.actaastro.2020.03.023
Autor:
George Makedonas, Hawley E. Kunz, Satish K. Mehta, Heather Quiriarte, Mayra Nelman-Gonzalez, Ramya Vangipuram, Brian Crucian, Stephen K. Tyring, Duane L. Pierson
Publikováno v:
Life Sciences in Space Research. 25:119-128
Background On long-duration spaceflight, most astronauts experience persistent immune dysregulation and the reactivation of latent herpesviruses, including varicella zoster virus (VZV). To understand the clinical risk of these perturbations to astron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bb260c3dc0f3b5b66c4561d33d0c7e
https://doi.org/10.1016/j.lssr.2019.10.001
https://doi.org/10.1016/j.lssr.2019.10.001
Autor:
Satish K. Mehta, David C. Bloom, Ianik Plante, Raymond Stowe, Alan H. Feiveson, Ashlie Renner, Adit Dhummakupt, Dhruv Markan, Ye Zhang, Honglu Wu, Blaire Scoles, Jeffrey I. Cohen, Brian Crucian, Duane L. Pierson
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2961 (2018)
Among the many stressors astronauts are exposed to during spaceflight, cosmic radiation may lead to various serious health effects. Specifically, space radiation may contribute to decreased immunity, which has been documented in astronauts during sho
Externí odkaz:
https://doaj.org/article/f3f2b3eb63234ef698b4fa4968262e8e