Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Duane L, Pierson"'
Autor:
Alexander A. Voorhies, C. Mark Ott, Satish Mehta, Duane L. Pierson, Brian E. Crucian, Alan Feiveson, Cherie M. Oubre, Manolito Torralba, Kelvin Moncera, Yun Zhang, Eduardo Zurek, Hernan A. Lorenzi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Abstract Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes and may have a negative impact on astronauts’ health. H
Externí odkaz:
https://doaj.org/article/a5cf7868343a469e881872fed67500f3
Autor:
Madhan R. Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah J. Bruce, C. Mark Ott, Duane L. Pierson, George E. Fox
Publikováno v:
npj Microgravity, Vol 3, Iss 1, Pp 1-9 (2017)
Evolution: Bacteria gain advantageous mutations under simulated microgravity Bacteria grown for an extended period of time under simulated microgravity adopt growth advantages. George Fox and colleagues from the University of Houston, Texas, USA, cul
Externí odkaz:
https://doaj.org/article/00446c7756a24031b3ea4ce32713b3c5
Autor:
Satish K. Mehta, Mark L. Laudenslager, Raymond P. Stowe, Brian E. Crucian, Alan H. Feiveson, Clarence F. Sams, Duane L. Pierson
Publikováno v:
npj Microgravity, Vol 3, Iss 1, Pp 1-8 (2017)
Virus reactivation in long-duration spaceflight Long-duration spaceflight increases the reactivation of latent herpes viruses in astronauts and is accompanied by a rise in stress hormone levels. This study shows that the frequency and viral loads of
Externí odkaz:
https://doaj.org/article/f32947e92776479e9e3b840364e87d36
Autor:
Madhan R. Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah J. Bruce, C. Mark Ott, Duane L. Pierson, George E. Fox
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The long-term response of microbial communities to the microgravity environment of space is not yet fully understood. Of special interest is the possibility that members of these communities may acquire antibiotic resistance. In this study,
Externí odkaz:
https://doaj.org/article/d91d94ba901144bea9787a024c551038
Autor:
Bridgette V. Rooney, Brian E. Crucian, Duane L. Pierson, Mark L. Laudenslager, Satish K. Mehta
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Latent herpes virus reactivation has been demonstrated in astronauts during shuttle (10–16 days) and International Space Station (≥180 days) flights. Following reactivation, viruses are shed in the body fluids of astronauts. Typically, shedding o
Externí odkaz:
https://doaj.org/article/4ebea70ba10d489f8235a42b17785591
Autor:
Brian E. Crucian, Alexander Choukèr, Richard J. Simpson, Satish Mehta, Gailen Marshall, Scott M. Smith, Sara R. Zwart, Martina Heer, Sergey Ponomarev, Alexandra Whitmire, Jean P. Frippiat, Grace L. Douglas, Hernan Lorenzi, Judith-Irina Buchheim, George Makedonas, Geoffrey S. Ginsburg, C. Mark Ott, Duane L. Pierson, Stephanie S. Krieger, Natalie Baecker, Clarence Sams
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight. It appears certain aspects of adaptive immunity are dysregulated du
Externí odkaz:
https://doaj.org/article/3004e90bcb074975994e73e64239391c
Autor:
Brian Crucian, Austin B. Bigley, Li Li, Katayoun Rezvani, Richard J. Simpson, Satish K. Mehta, Preteesh L. Mylabathula, Mitzi S. Laughlin, Melissa M. Markofski, Duane L. Pierson
Publikováno v:
Acta Astronautica. 174:32-40
Long-duration spaceflight impairs natural killer (NK) cell function, which could compromise immune surveillance in exploration class mission crew. To determine if microgravity can impair NK-cell function, we established a rotary cell culture system t
Autor:
George Makedonas, Hawley E. Kunz, Satish K. Mehta, Heather Quiriarte, Mayra Nelman-Gonzalez, Ramya Vangipuram, Brian Crucian, Stephen K. Tyring, Duane L. Pierson
Publikováno v:
Life Sciences in Space Research. 25:119-128
Background On long-duration spaceflight, most astronauts experience persistent immune dysregulation and the reactivation of latent herpesviruses, including varicella zoster virus (VZV). To understand the clinical risk of these perturbations to astron
Autor:
Satish K. Mehta, David C. Bloom, Ianik Plante, Raymond Stowe, Alan H. Feiveson, Ashlie Renner, Adit Dhummakupt, Dhruv Markan, Ye Zhang, Honglu Wu, Blaire Scoles, Jeffrey I. Cohen, Brian Crucian, Duane L. Pierson
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2961 (2018)
Among the many stressors astronauts are exposed to during spaceflight, cosmic radiation may lead to various serious health effects. Specifically, space radiation may contribute to decreased immunity, which has been documented in astronauts during sho
Externí odkaz:
https://doaj.org/article/f3f2b3eb63234ef698b4fa4968262e8e
Autor:
Duane L. Pierson, Kelvin J. Moncera, Manolito Torralba, Yun Zhang, Cherie Oubre, Hernan Lorenzi, C. Mark Ott, Brian Crucian, Alexander A. Voorhies, Satish K. Mehta, Alan H. Feiveson, Eduardo E. Zurek
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes and may have a negative impact on astronauts’ health. Here we in