Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Duane C. Bloedow"'
Autor:
Duane C. Bloedow, Paul J. Fielder, Wati Dimjati, Karen J. Neelis, Gerard Wagemaker, Trudi P. Visser, G. Roger Thomas, Dan L. Eaton
Publikováno v:
Blood. 92:1586-1597
Thrombopoietin (TPO) has been used in preclinical myelosuppression models to evaluate the effect on hematopoietic reconstitution. Here we report the importance of dose and dose scheduling for multilineage reconstitution after myelosuppressive total b
Autor:
John O. Ike, Andrew R. Hoffman, Raymond L. Hintz, Duane C. Bloedow, Neil Gesundheit, Fernando C. Fervenza, Ralph Rabkin, Helen Maidment, Frances Liu
Publikováno v:
Kidney International. 49:1134-1140
Pharmacokinetics of insulin-like growth factor-1 in advanced chronic renal failure. Information regarding the impact of chronic renal failure (CRF) on IGF-1 serum clearance is limited. Thus we evaluated the pharmacokinetics of insulin-like growth fac
Publikováno v:
Journal of Pharmaceutical Sciences. 84:575-580
This study was designed to provide information on the tissue distribution and elimination of recombinant human interleukin‐1 receptor antagonist (rhIL‐1ra) in rats. Following intravenous (iv) bolus administration of metabolically labeled [ 35 S]r
Autor:
Alexander V. Lyubimov, Aryamitra Banerjee, Alexei A. Bogdanov, Akiko Nishimoto-Ashfield, Elijah M. Bolotin, Manshun Lai, Israel Rubinstein, Duane C. Bloedow, Cynthia C. Jones, Sandra Reichstetter, Gerardo M. Castillo
Publikováno v:
Pharmaceutical research. 30(3)
To determine and compare pharmacokinetics and toxicity of two nanoformulations of Vasoactive Intestinal Peptide (VIP). VIP was formulated using a micellar (Sterically Stabilized Micelles, SSM) and a polymer-based (Protected Graft Copolymer, PGC) nano
Autor:
Duane C. Bloedow, Charles A. Dinarello, Michael A. Catalano, David M. Stiles, Sheldon M. Wolff, Eric V. Granowitz, James W. Mier, Reuven Porat, John P. Pribble
Publikováno v:
Cytokine. 4:353-360
A phase I study of human recombinant interleukin-1 receptor antagonist (IL-1ra) was conducted in healthy males between the ages of 18 and 30. Twenty-five volunteers received a single, 3 h continuous intravenous infusion of doses ranging between 1 mg/
Autor:
Duane C. Bloedow, Alexei A. Bogdanov, Israel Rubinstein, Cynthia C. Jones, Alexander V. Lyubimov, Manshun Lai, Gerardo M. Castillo, Sandra Reichstetter, Akiko Nishimoto-Ashfield, Aryamitra Banerjee, Elijah M. Bolotin
Publikováno v:
Pharmaceutical Research. 30:1939-1939
Autor:
Duane C. Bloedow, Per-Olof Hasselgren, Josef E. Fischer, Zamir O, William O'Brien, Robert Thompson
Publikováno v:
The International journal of biochemistry. 26(7)
1. 1. The role ofinterleukin-1 (IL-1) in sepsis-induced muscle proteolysis was assessed by treating septic rats with recombinant IL-1 receptor antagonist (rIL-Ira). 2. 2. In initial experiments, we tested the effectiveness of IL-Ira in preventing mus
Publikováno v:
Journal of ocular pharmacology. 10(4)
Flurbiprofen Na and diclofenac Na, two ocular antiinflammatory agents, were investigated to determine the aqueous humor concentrations in the human eye following topical application. One hundred sixty-five patients undergoing cataract surgery receive
Publikováno v:
Journal of pharmaceutical sciences. 81(3)
We studied the effect of manual nasolacrimal occlusion on the concentration of timolol in the aqueous humor of eyes of patients undergoing cataract extraction. Aqueous humor samples were obtained at various times after timolol maleate instillation fr
Autor:
Gary L. Larsen, Malcolm R. Hill, Stanley J. Szefler, Duane C. Bloedow, Pakit Vichyanond, Charles G. Irvin, Leon S. Greos
Publikováno v:
The American review of respiratory disease. 144(3 Pt 1)
Previous studies in humans and rabbits demonstrated that methylprednisolone appears in the lung in greater concentration than prednisolone. To ascertain which pharmacokinetic properties of these drugs explain this difference, we gave methylprednisolo