Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Duane C Hassane"'
Autor:
Mayumi Sugita, Roman Galetto, Hongliang Zong, Nathan Ewing-Crystal, Vicenta Trujillo-Alonso, Nuria Mencia-Trinchant, Winnie Yip, Stephanie Filipe, Celine Lebuhotel, Agnès Gouble, Duane C. Hassane, Julianne Smith, Gail J. Roboz, Monica L. Guzman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
CD123, the interleukin-3 receptor alpha chain, is aberrantly expressed in acute myeloid leukemia blasts and leukemia stem cells. Here the authors report the design and characterize the anti-tumor activity of allogeneic CD123-targeted CAR-T cells as a
Externí odkaz:
https://doaj.org/article/45f0693affa74393899beaac1aead79c
Autor:
Mayumi Sugita, David C. Wilkes, Rohan Bareja, Kenneth W. Eng, Sarah Nataraj, Reyna A. Jimenez-Flores, LunBiao Yan, Jeanne Pauline De Leon, Jaclyn A. Croyle, Justin Kaner, Swathi Merugu, Sahil Sharma, Theresa Y. MacDonald, Zohal Noorzad, Palak Panchal, Danielle Pancirer, Shuhua Cheng, Jenny Z. Xiang, Luke Olson, Koen Van Besien, David S. Rickman, Susan Mathew, Wayne Tam, Mark A. Rubin, Himisha Beltran, Andrea Sboner, Duane C. Hassane, Gabriela Chiosis, Olivier Elemento, Gail J. Roboz, Juan Miguel Mosquera, Monica L. Guzman
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-10 (2021)
Abstract The epichaperome is a new cancer target composed of hyperconnected networks of chaperome members that facilitate cell survival. Cancers with an altered chaperone configuration may be susceptible to epichaperome inhibitors. We developed a flo
Externí odkaz:
https://doaj.org/article/9b26f08bf6d444edb5f3140c7fcddf4c
Autor:
Juan Carlos Balandrán, José Dávila-Velderrain, Antonio Sandoval-Cabrera, Gabriela Zamora-Herrera, Vanessa Terán-Cerqueda, Lilia Adela García-Stivalet, José Alejandro Limón-Flores, Erick Armenta-Castro, Aurora Rodríguez-Martínez, Bertha Alicia Leon-Chavez, Verónica Vallejo-Ruiz, Duane C. Hassane, Sonia Mayra Pérez-Tapia, Vianney Ortiz-Navarrete, Monica L. Guzman, Rosana Pelayo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B-cell acute lymphoblastic leukemia (B-ALL) results from the expansion of malignant lymphoid precursors within the bone marrow (BM), where hematopoietic niches and microenvironmental signals provide leukemia-initiating cells (LICs) the conditions to
Externí odkaz:
https://doaj.org/article/6caa116391044fefa37ea44363f1c043
Autor:
Afaf E. G. Osman, Nuria Mencia-Trinchant, Caner Saygin, Luke Moma, Aelin Kim, Genevieve Housman, Matthew Pozsgai, Eti Sinha, Pooja Chandra, Duane C. Hassane, Andrea Sboner, Kishan Sangani, Nick DiNardi, Christopher Johnson, Sara S. Wallace, Bana Jabri, Hue Luu, Monica L. Guzman, Pinkal Desai, Lucy A. Godley
Publikováno v:
Blood Advances. 7:1910-1914
Clonal hematopoiesis (CH) represents clonal expansion of mutated hematopoietic stem cells detectable in the peripheral blood or bone marrow through next generation sequencing. The current prevailing model posits that CH mutations detected in the peri
Autor:
Nuria Mencia-Trinchant, Matthew J. MacKay, Christopher Chin, Ebrahim Afshinnekoo, Jonathan Foox, Cem Meydan, Daniel Butler, Christopher Mozsary, Nicholas A. Vernice, Charlotte Darby, Michael C. Schatz, Susan M. Bailey, Ari M. Melnick, Monica L. Guzman, Kelly Bolton, Lior Z. Braunstein, Francine Garrett-Bakelman, Ross L. Levine, Duane C. Hassane, Christopher E. Mason
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108740- (2021)
Externí odkaz:
https://doaj.org/article/26eb80a01d55442d8a4e86c2c9ec63fa
Autor:
Duane C. Hassane, Gail J. Roboz, Guido Marcucci, Ross L. Levine, Omar Abdel-Wahab, Ulrich Steidl, Michael W. Becker, Craig T. Jordan, Cheryl A. Corbett, Marlene Balys, Krishan K. Sharma, Neng Yang, Monica L. Guzman
PDF - 1495K, Quantification for the immunoblots shown in figure 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be69c265959314ef182b66c00dfd9cf
https://doi.org/10.1158/1535-7163.22500021
https://doi.org/10.1158/1535-7163.22500021
Autor:
Duane C. Hassane, Gail J. Roboz, Guido Marcucci, Ross L. Levine, Omar Abdel-Wahab, Ulrich Steidl, Michael W. Becker, Craig T. Jordan, Cheryl A. Corbett, Marlene Balys, Krishan K. Sharma, Neng Yang, Monica L. Guzman
PDF - 3889K, AR-42 demonstrates higher activity against a panel of leukemia cell lines in contrast to PTL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034552bed5faf5c66d5d313104cd8458
https://doi.org/10.1158/1535-7163.22500030.v1
https://doi.org/10.1158/1535-7163.22500030.v1
Autor:
Duane C. Hassane, Gail J. Roboz, Guido Marcucci, Ross L. Levine, Omar Abdel-Wahab, Ulrich Steidl, Michael W. Becker, Craig T. Jordan, Cheryl A. Corbett, Marlene Balys, Krishan K. Sharma, Neng Yang, Monica L. Guzman
PDF - 962K, Reactome gene list.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7ccf29a1802e4fca8e8986065a6d79
https://doi.org/10.1158/1535-7163.22500003
https://doi.org/10.1158/1535-7163.22500003
Autor:
Duane C. Hassane, Gail J. Roboz, Guido Marcucci, Ross L. Levine, Omar Abdel-Wahab, Ulrich Steidl, Michael W. Becker, Craig T. Jordan, Cheryl A. Corbett, Marlene Balys, Krishan K. Sharma, Neng Yang, Monica L. Guzman
Most patients with acute myelogenous leukemia (AML) relapse and die of their disease. Increasing evidence indicates that AML relapse is driven by the inability to eradicate leukemia stem cells (LSC). Thus, it is imperative to identify novel therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9a1d44d0e83a1b684f06a78e6a11ce
https://doi.org/10.1158/1535-7163.c.6536325
https://doi.org/10.1158/1535-7163.c.6536325
Autor:
Duane C. Hassane, Gail J. Roboz, Guido Marcucci, Ross L. Levine, Omar Abdel-Wahab, Ulrich Steidl, Michael W. Becker, Craig T. Jordan, Cheryl A. Corbett, Marlene Balys, Krishan K. Sharma, Neng Yang, Monica L. Guzman
PDF - 306K, Differentially expressed genes upon AR-42 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078dc9491443ded20f5a1e471bff96a1
https://doi.org/10.1158/1535-7163.22500000.v1
https://doi.org/10.1158/1535-7163.22500000.v1