Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Duane Abbott"'
Publikováno v:
Antioxidants & Redox Signaling. 11:1313-1333
Subcellular compartmentalization of reactive oxygen species (ROS) plays a critical role in transmitting cell signals in response to environmental stimuli. In this regard, signals at the plasma membrane have been shown to trigger NADPH oxidase-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0209025127e987afce92531d6746047
https://doi.org/10.1089/ars.2008.2363
https://doi.org/10.1089/ars.2008.2363
Autor:
Duane Abbott, Qiang Li, John F. Engelhardt, Weihong Zhou, Chenguang Fan, Yulong Zhang, Meihui Luo, Xiaoming Liu
Publikováno v:
Journal of Clinical Investigation. 113:746-755
IκB proteins play an important role in regulating NF-κB induction following a diverse range of environmental injuries. Studies evaluating IκBβ knock-in mice (AKBI), in which the Iκ κ Bα α gene is replaced by the Iκ κ Bβ β cDNA, have uncov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b402341c303faed372c2f4159ecea7b9
https://doi.org/10.1172/jci17337
https://doi.org/10.1172/jci17337
Publikováno v:
Journal of Biological Chemistry. 277:33398-33410
Members of the Wnt family of secreted molecules have been established as key factors in determining cell fate and morphogenic signaling. It has long been recognized that Wnt induces morphogenic signaling through the Tcf/LEF-1 cascade by regulating fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555a867efb8c6f88bfb09f37e91ea992
https://doi.org/10.1074/jbc.m107977200
https://doi.org/10.1074/jbc.m107977200
Autor:
Weihong Zhou, Botond Banfi, Qiang Li, Duane Abbott, John F. Engelhardt, Yulong Zhang, Meihui Luo, Thomas J. Lynch, Netanya Y. Spencer, Ziying Yan
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 305(1)
Cell line studies have previously demonstrated that hypoxia-reoxygenation (H/R) leads to the production of NADPH oxidase 1 and 2 (NOX1 and NOX2)-dependent reactive oxygen species (ROS) required for the activation of c-Src and NF-κB. We now extend th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a1bc0d0bbeded4a56d9093cfb6fff0
https://pubmed.ncbi.nlm.nih.gov/23639811
https://pubmed.ncbi.nlm.nih.gov/23639811
Autor:
John F. Engelhardt, Qiang Li, Weihong Zhou, Duane Abbott, Botond Banfi, Netanya Y. Spencer, Yulong Zhang
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::910bbd638cb3aa23c12a4539fa243fcd
https://doi.org/10.1096/fasebj.27.1_supplement.682.12
https://doi.org/10.1096/fasebj.27.1_supplement.682.12
Autor:
Ningli Cheng, Vladimir Leontiev, Xiaoming Liu, John F. Engelhardt, Duane Abbott, Mohammed Filali
Publikováno v:
Mucus Hypersecretion in Respiratory Disease: Novartis Foundation Symposium 248
Submucosal glands (SMGs) are thought to play an important role in the pathogenesis of a number of hypersecretory lung diseases including cystic fibrosis, asthma, and chronic bronchitis. In such diseases, severe SMG hypertrophy and hyperplasia is char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec19f782b61aa267d3877ff9b49f620
https://doi.org/10.1002/0470860790.ch4
https://doi.org/10.1002/0470860790.ch4
Rac-dependent NADPH oxidases generate reactive oxygen species used in cell signaling and microbial killing or both. Whereas the mechanisms leading to NADPH oxidase activation are fairly well studied, the mechanisms that control downregulation of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955c4473d1bbd665234cdd351f55b567
https://europepmc.org/articles/PMC3597076/
https://europepmc.org/articles/PMC3597076/
Autor:
Ningli Cheng, Mohammed Filali, John F. Engelhardt, Ryan R. Driskell, Duane Abbott, Weihong Zhou, Chris Moothart, Xiaoming Liu, Curt D. Sigmund, Meihui Luo
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 287(4)
Regulated expression of lymphoid enhancer factor 1 (Lef-1) plays an obligatory role in the transcriptional control of epithelial bud formation during airway submucosal gland and mammary gland development. However, regions of the Lef-1 promoter requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d145c45080e27aa4eba41a73bdd166
https://pubmed.ncbi.nlm.nih.gov/15194563
https://pubmed.ncbi.nlm.nih.gov/15194563
Autor:
Mohammed, Filali, Xiaoming, Liu, Ningli, Cheng, Duane, Abbott, Vladimir, Leontiev, John F, Engelhardt
Publikováno v:
Novartis Foundation symposium. 248
Submucosal glands (SMGs) are thought to play an important role in the pathogenesis of a number of hypersecretory lung diseases including cystic fibrosis, asthma, and chronic bronchitis. In such diseases, severe SMG hypertrophy and hyperplasia is char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::607e276deff5affd1df88d0693c469d0
https://pubmed.ncbi.nlm.nih.gov/12568487
https://pubmed.ncbi.nlm.nih.gov/12568487
Autor:
Chenguang, Fan, Qiang, Li, Yulong, Zhang, Xiaoming, Liu, Meihui, Luo, Duane, Abbott, Weihong, Zhou, John F, Engelhardt
Publikováno v:
The Journal of clinical investigation. 113(5)
IkappaB proteins play an important role in regulating NF-kappaB induction following a diverse range of environmental injuries. Studies evaluating IkappaBbeta knock-in mice (AKBI), in which the IkappaBalpha gene is replaced by the IkappaBbeta cDNA, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e41dcf712e9dfd943b14fcf2fd442b6
https://pubmed.ncbi.nlm.nih.gov/14991073
https://pubmed.ncbi.nlm.nih.gov/14991073