Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Duane A. Sewell"'
Publikováno v:
The Journal of Immunology. 182:5537-5546
Thirty years after angiogenesis was shown to play an enabling role in cancer, modern medicine is still trying to develop novel compounds and therapeutics to target the tumor vasculature. However, most therapeutics require multiple rounds of administr
Publikováno v:
Acta Oto-Laryngologica. 128:583-589
Conclusion. Our results indicate that viral load may serve as an independent prognostic indicator for patients with HPV-16-associated squamous cell carcinoma of the tonsil. Objective. HPV-16 has gained increasing attention as a possible causative age
Publikováno v:
Ear, Nose & Throat Journal. 86:506-511
The presence of tumor-infiltrating lymphocytes has been shown to significantly improve clinical outcomes in many types of cancer. However, their effects on outcomes in patients with oropharyngeal cancer specifically have yet to be elucidated. We cond
Publikováno v:
ORL. 69:77-84
Laryngeal cancer remains a worldwide health problem. The identification of biomarkers unique to laryngeal cancer may provide new insights into its pathogenesis, as well as provide potential targets for novel therapies and early detection. In order to
Autor:
Yvonne Paterson, George R. Gunn, Zhen-Kun Pan, Vafa Shahabi, Duane A. Sewell, Mary E. Dominiecki
Publikováno v:
Cancer Research. 64:8821-8825
Previous work in our laboratory has established that the fusion of tumor-associated antigens to a truncated form of the Listeria monocytogenes virulence factor listeriolysin O (LLO) enhances the immunogenicity and antitumor efficacy of the tumor anti
Autor:
Todd W. Hessel, Duane A. Sewell, Michael Griswold, Nishant Agrawal, Steven M. Frank, David W. Eisele
Publikováno v:
The Laryngoscope. 113:1278-1282
Objective: To determine the predictors and incidence of hypothermia in patients undergoing head and neck surgery. Study Design: Retrospective analysis. Methods: Patients were either not warmed (n = 43) or actively warmed with forced-air warming (n =
Autor:
Duane A. Sewell
Publikováno v:
Operative Techniques in Otolaryngology-Head and Neck Surgery. 14:27-33
The supracricoid partial laryngectomy (SCPL) with cricohyoidopexy (CHP) is an alternative to total laryngectomy in the treatment of selected glottic and supraglottic cancers. It consists of the resection of the true cords, false cords, thyroid cartil
Publikováno v:
Vaccine. 29(47)
Bone marrow (BM) serves as a reservoir for a unique population of memory T cells with strong effector properties that make them ideal targets for cancer immunotherapy strategies. However, direct vaccination and priming of T cells within the BM of the
Autor:
Paulus Mrass, Hildegund C.J. Ertl, Marcio O. Lasaro, Wolfgang Weninger, Yvonne Paterson, Marina Sazanovich, Wynetta Giles-Davis, Duane A. Sewell, S. Farzana Hussain, Yang Xin Fu, Ralph M. Bunte
Vaccines that aim to expand tumor-specific CD8(+) T cells have yielded disappointing results in cancer patients although they showed efficacy in transplantable tumor mouse models. Using a system that more faithfully mimics a progressing cancer and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc45b05d17503a42cde3c65ba657ca7
https://europepmc.org/articles/PMC3182366/
https://europepmc.org/articles/PMC3182366/
Publikováno v:
Vaccine. 26(41)
We have shown that Listeria-based cancer vaccines inhibit the growth of transplanted tumors in a transgenic mouse model of immune tolerance where HPV-16 E7 is expressed in the thyroid gland. In this study we determine whether these vaccines are able