Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Duane A. Chung"'
Autor:
Duane A. Chung, Shane Kilpatrick, Dragan Miscevic, Murray Moo-Young, C. Perry Chou, Teshager Kefale, Kajan Srirangan
Publikováno v:
Metabolic engineering. 61
3-Hydroxyacids are a group of valuable fine chemicals with numerous applications, and 3-hydroxybutyrate (3-HB) represents the most common species with acetyl-CoA as a precursor. Due to the lack of propionyl-CoA in most, if not all, microorganisms, bi
Publikováno v:
Applied and Environmental Microbiology. 82:6109-6119
The discovery and exploitation of the prokaryotic adaptive immunity system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins have revolutionized genetic engineering. CRISPR-Cas tools hav
Autor:
Duane A. Chung, Mark Bruder, Stanislav Sokolenko, C. Perry Chou, Marc G. Aucoin, Xuejia Liu, Kajan Srirangan, Michael E. Pyne, Murray Moo-Young
Publikováno v:
Applied and Environmental Microbiology. 82:5375-5388
Crude glycerol, the major by-product of biodiesel production, is an attractive bioprocessing feedstock owing to its abundance, low cost, and high degree of reduction. In line with the advent of the biodiesel industry, Clostridium pasteurianum has gai
Publikováno v:
Applied and Environmental Microbiology. 81:5103-5114
To date, most genetic engineering approaches coupling the type II Streptococcus pyogenes clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system to lambda Red recombineering have involved minor single nucleotide mutations. Here
Publikováno v:
Scientific Reports
Clostridium pasteurianum is emerging as a prospective host for the production of biofuels and chemicals, and has recently been shown to directly consume electric current. Despite this growing biotechnological appeal, the organism’s genetics and cen
Publikováno v:
Scientific Reports
Application of CRISPR-Cas9 systems has revolutionized genome editing across all domains of life. Here we report implementation of the heterologous Type II CRISPR-Cas9 system in Clostridium pasteurianum for markerless genome editing. Since 74% of spec
Publikováno v:
Fermentation
Volume 1
Issue 1
Pages: 113-126
Volume 1
Issue 1
Pages: 113-126
Clostridium pasteurianum is receiving growing attention for its unique metabolic properties, particularly its ability to convert waste glycerol and glycerol-rich byproducts into butanol, a prospective biofuel. Genetic tool development and whole genom
Publikováno v:
Applied microbiology and biotechnology. 99(18)
The industrial Gram-positive anaerobe Clostridium acetobutylicum is a valued acetone, butanol, and ethanol (ABE) solvent producer that is able to utilize a vast array of carbon sources in fermentation. When glucose is present in the growth medium, ho
Publikováno v:
Cell Biology and Toxicology. 20:147-169
Previous studies showed that the pesticide lindane (gamma-hexachlorocyclohexane) inhibits gap junction intercellular communication in rat myometrial cells. The present study tested the hypothesis that lindane and the phorbol ester 12-O-tetradecanoylp
Autor:
Duane A. Chung, Carol B. Fowler, Erik R. P. Zuiderweg, Richard R. Neubig, Orkun S. Soyer, Henry I. Mosberg
Publikováno v:
Biochemistry. 41:3596-3604
A major, unresolved question in signal transduction by G protein coupled receptors (GPCRs) is to understand how, at atomic resolution, a GPCR activates a G protein. A step toward answering this que...