Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Duana Carvalho dos Santos"'
Autor:
Flavia Karine Rigo, Mateus Fortes Rossato, Vanessa Borges, Juliana Figueira da Silva, Elizete Maria Rita Pereira, Ricardo Andrez Machado de Ávila, Gabriela Trevisan, Duana Carvalho dos Santos, Danuza Montijo Diniz, Marco Aurélio Romano Silva, Célio José de Castro Junior, Thiago Mattar Cunha, Juliano Ferreira, Marcus Vinicius Gomez
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
ABSTRACT Background: Intrathecal injection of voltage-sensitive calcium channel blocker peptide toxins exerts analgesic effect in several animal models of pain. Upon intrathecal administration, recombinant Phα1β exerts the same analgesic effects as
Externí odkaz:
https://doaj.org/article/3a6a31d0259a4d89a0d327cf5d52aa15
Autor:
Célio José de Castro Junior, Duana Carvalho dos Santos, Marcio Junior S. Rezende, Mariana Peluci Garcia Mendes, Luana Assis Ferreira, Marcus Vinicius Gomez, Flávia Karine Rigo
Publikováno v:
Toxicon. 195:104-110
This study investigated the effects of intravenous (iv) administration of recombinant Phα1β toxin, pregabalin, and diclofenac by the intrathecal route using an animal model fibromyalgia (FM). The reserpine administration (0.25 mg/kg s. c) once dail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbd971af978ba9676d9b47bfe9bf680
https://doi.org/10.1016/j.toxicon.2021.03.012
https://doi.org/10.1016/j.toxicon.2021.03.012
Autor:
Duana Carvalho dos Santos, Marcus Vinicius Gomez, Rodrigo Antônio Andrade Moura, Caio Tavares Aoki, Mariana Peluci Garcia Mendes, Celio J. Castro-Junior, Luana Assis Ferreira, Marcio Junior S. Rezende
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 27, Article number: e20210027, Published: 25 AUG 2021
Journal of Venomous Animals and Toxins including Tropical Diseases v.27 2021
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases v.27 2021
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Background: Phoneutria nigriventer venom contains Phα1β. This toxin and its recombinant form have a remarkable analgesic potential that is associated with blockage of voltage-gated calcium channels and TRPA1 receptors. Although morphine is a mainst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca222fe082d151f5917a597ea44f0473
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100319&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100319&lng=en&tlng=en
Autor:
Ricardo Andrez Machado de Ávila, Gabriela Trevisan, Elizete Maria Rita Pereira, Marco Aurélio Romano Silva, Duana Carvalho dos Santos, Vanessa Araujo Borges, Marcus Vinicius Gomez, Flávia Karine Rigo, Mateus Rossato, Juliano Ferreira, Juliana Figueira da Silva, Danuza Montijo Diniz, Célio J. Castro, Thiago M. Cunha
Publikováno v:
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases v.26 2020
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 26, Article number: e20190070, Published: 17 APR 2020
Journal of Venomous Animals and Toxins including Tropical Diseases v.26 2020
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 26, Article number: e20190070, Published: 17 APR 2020
Background: Intrathecal injection of voltage-sensitive calcium channel blocker peptide toxins exerts analgesic effect in several animal models of pain. Upon intrathecal administration, recombinant Phα1β exerts the same analgesic effects as the thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869a1f177548fa5b257ad69dc3e27e51
https://pubmed.ncbi.nlm.nih.gov/32362927
https://pubmed.ncbi.nlm.nih.gov/32362927
Autor:
Marcelo Araújo Buzelin, Elizete Maria Rita Pereira, Vanice Paula Ricardo Carvalho, Duana Carvalho dos Santos, André Luiz Senna Guimarães, Danuza Montijo Diniz, Nancy Scardua Binda, Juliana Figueira da Silva, Márcia Helena Borges, Marcus Vinicius Gomez, Cláudio Antônio da Silva Júnior
Publikováno v:
European journal of pharmacology. 891
Agents that modulate the activity of high-voltage gated calcium channels (HVCCs) exhibit experimentally and clinically significant effect by relieving visceral pain. Among these agents, the toxins Phα1β and ω-conotoxin MVIIA effectively reduce chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd0f25ac58b6ce59788dbc14ab4a3c6
https://pubmed.ncbi.nlm.nih.gov/33190801
https://pubmed.ncbi.nlm.nih.gov/33190801
Autor:
Célio José de Castro Junior, Marcio Junior S. Rezende, Marcus Vinicius Gomez, Luana Assis Ferreira, Juliano Ferreira, Marina A Delgado, Duana Carvalho dos Santos, Rodrigo Antônio Andrade Moura, Mariana Peluci Mendes, Caio Tavares Aoki
Publikováno v:
Life Sciences. 278:119582
Opioids are the first-line treatment for cancer pain. Incomplete pain relief and the high rate of adverse effects of these compounds bring a need to combine them with other drugs acting on different targets. Aims We here evaluate the antinociceptive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efd2149d6bc848cbf93ce06e9ecb797
https://doi.org/10.1016/j.lfs.2021.119582
https://doi.org/10.1016/j.lfs.2021.119582
Autor:
Duana Carvalho dos Santos, Célio José de Castro Junior, Juliano Ferreira, Marcus Vinicius Gomez, Juliana Figueira da Silva, Manuella R. Palhares, Cláudio A. Silva-Junior
Publikováno v:
Data in Brief, Vol 14, Iss C, Pp 440-452 (2017)
Data in Brief
Data in Brief
Determining antinociceptive interaction between Phα1β toxin (a voltage gated calcium channel blocker) and SB366791 (selective TRPV1 antagonist) may have both clinical and mechanistic implications for the pain management. This data in brief article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863e9f0d3ad23d4dc76532fb7b4f93e5
http://www.sciencedirect.com/science/article/pii/S235234091730361X
http://www.sciencedirect.com/science/article/pii/S235234091730361X
Autor:
Marcus Vinicius Gomez, Duana Carvalho dos Santos, Juliana Figueira da Silva, Cláudio A. Silva-Junior, Juliano Ferreira, Manuella R. Palhares, Celio J. Castro-Junior, Marcio Junior S. Rezende, Márcia Helena Borges
Publikováno v:
Life Sciences. 182:122-128
Aims Extensive evidence supports a role for voltage-gated calcium channels (VGCC) and TRPV1 receptors in pain transmission and modulation. We investigated the profile of analgesic interaction between Phα1β toxin (a VGCC blocker) and SB366791 (selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bdeadb76f5908d908e21bd6f5ed82b
https://doi.org/10.1016/j.lfs.2017.06.018
https://doi.org/10.1016/j.lfs.2017.06.018
Autor:
Silvia Guatimosim, Duana Carvalho dos Santos, Flavia Lage Pessoa da Costa, Célio José de Castro Junior, Mauro Cunha Xavier Pinto, Luana Assis Ferreira, Natália Virtude Carobin, Itamar Couto Guedes de Jesus, Juliana Figueira da Silva
Publikováno v:
Biochemical Pharmacology. 182:114210
TRPV1 is a cation channel expressed in peripheral nociceptive pathways and its activation can trigger nociception signals to the brain. Ketamine is an intravenous anesthetic routinely used for anesthesia induction and with potent analgesic activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d44b928e222d98fadb55a1bb4aba5f
https://doi.org/10.1016/j.bcp.2020.114210
https://doi.org/10.1016/j.bcp.2020.114210
Autor:
Nancy Scardua Binda, Ronaldo Alves Pinto Nagem, Cláudio Antônio da Silva Júnior, Fabiola M. Ribeiro, Duana Carvalho dos Santos, Márcia Helena Borges, Juliana Figueira da Silva, Natália Virtude Carobin, Marcus Vinicius Gomez, Juliano Ferreira, Christopher Kushmerick, Jessica M. de Souza, Elizete Maria Rita Pereira, Célio José de Castro Junior
Publikováno v:
Neuropharmacology. 162:107826
Capsaicin, an agonist of TRPV1, evokes intracellular [Ca2+] transients and glutamate release from perfused trigeminal ganglion. The spider toxin PnTx3-5, native or recombinant is more potent than the selective TRPV1 blocker SB-366791 with IC50 of 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f54a0a6088bf50ac3d7b896ccbbeafa
https://doi.org/10.1016/j.neuropharm.2019.107826
https://doi.org/10.1016/j.neuropharm.2019.107826