Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Duan-Jun Tan"'
Publikováno v:
Oncology Reports. 30:757-762
Insulin-like growth factor 1 (IGF-1) is a molecule with strong proliferative effects, and statins have been reported to exhibit antitumor effects based on clinical and experimental studies. However, their effects on cardiac myxoma (CM) cells and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b935cb61aeb500a5f095e78cda94ab4
https://doi.org/10.3892/or.2013.2501
https://doi.org/10.3892/or.2013.2501
Autor:
Roy Anthony Orden, David Goerlitz, Ramona G. Dumitrescu, Françoise Seillier-Moiseiwitsch, Stephanie M. Spernak, Dingfen Han, Duan-Jun Tan, Jinguo Chen, Radoslav Goldman, Peter G. Shields
Publikováno v:
Carcinogenesis
DNA alterations in mitochondria are believed to play a role in carcinogenesis and are found in smoking-related cancers. We sought to replicate earlier findings for the association of smoking with increased mitochondrial DNA (mtDNA) content in buccal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6fab9e1a49c51f4e5470f160022bd9
https://doi.org/10.1093/carcin/bgn034
https://doi.org/10.1093/carcin/bgn034
Publikováno v:
Breast Cancer Online. 9:1-11
Breast cancer is a multifactorial disease that is triggered by gene–environment interactions. Epidemiological research has identified alcohol consumption as a significant non-hormonal-related and consistent risk factor, and is thus a preventable ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced8e7c3c5070979bd57f9dfa94e16e7
https://doi.org/10.1017/s1470903106003105
https://doi.org/10.1017/s1470903106003105
Publikováno v:
ELECTROPHORESIS. 25:2602-2610
Mitochondrial disorders are a group of clinically and genetically heterogeneous diseases. Common recurrent mitochondrial DNA (mtDNA) point mutations account for the molecular defects of a small proportion of patients. In order to identify mtDNA mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4190d79083a8844632c4729c9f9fb326
https://doi.org/10.1002/elps.200406016
https://doi.org/10.1002/elps.200406016
Publikováno v:
Clinical Chemistry. 48:1901-1912
Background: Definitive molecular diagnosis of mitochondrial disorders has been greatly hindered by the tremendous clinical and genetic heterogeneity, the heteroplasmic condition of pathogenic mutations, and the presence of numerous homoplasmic mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cace39dec6d4a02421696d018081ac
https://doi.org/10.1093/clinchem/48.11.1901
https://doi.org/10.1093/clinchem/48.11.1901
Autor:
Lee-Jun C. Wong, Pu Dai, Art Grix, Mark H. Lipson, Duan-Jun Tan, Mara Sifry-Platt, Andrea L. Gropman, Tian-Jian Chen
Publikováno v:
American Journal of Medical Genetics. 102:95-99
We report the first frame-shift truncation mutation in a mitochondrial DNA (mtDNA)-encoded subunit II of cytochrome c oxidase (COXII). The mutation was identified by temporal temperature gradient gel electrophoresis (TTGE) followed by direct DNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a81003b7a22ed1c1b31c3e914041618
https://doi.org/10.1002/1096-8628(20010722)102:1<95::aid-ajmg1412>3.0.co
https://doi.org/10.1002/1096-8628(20010722)102:1<95::aid-ajmg1412>3.0.co
Autor:
Kun-Tu Yeh, Ren-Kui Bai, Julia Chang, Hao Liu, Lee-Jun C. Wong, Duan-Jun Tan, Mary Ann Lou, Jyh-Feng Lu
Publikováno v:
Journal of Oncology, Vol 2011 (2011)
Journal of Oncology
Journal of Oncology
Changes in mitochondrial DNA (mtDNA) content in cancers have been reported with controversial results, probably due to small sample size and variable pathological conditions. In this study, mtDNA content in 302 breast tumor/surrounding normal tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1046fb52f7d423f184a67d732a5ebff0
Autor:
Duan-Jun Tan, Avril Sloane, Ren-Kui Bai, Annette Feigenbaum, Ernest Cutz, Brian H. Robinson, Lee-Jun C. Wong, Haeyoung Kwon, Emily S Doherty
Publikováno v:
American journal of medical genetics. Part A. 140(20)
Patients with mitochondrial disease usually manifest multisystemic dysfunction with a broad clinical spectrum. When the tests for common mitochondrial DNA (mtDNA) point mutations are negative and the mtDNA defects are still hypothesized, it is necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80b804d4d6dc1cdb6dfbd3f6a13c3ae
https://pubmed.ncbi.nlm.nih.gov/16955414
https://pubmed.ncbi.nlm.nih.gov/16955414
Autor:
Yu-Fen Wang, Julia Chang, Ling-Ling Liu, Duan-Jun Tan, Ren-Kui Bai, Lee-Jun C. Wong, Kun-Tu Yeh
Publikováno v:
BMC Cancer, Vol 6, Iss 1, p 93 (2006)
BMC Cancer
BMC Cancer
BackgroundThe roles of mitochondria in energy metabolism, the generation of ROS, aging, and the initiation of apoptosis have implicated their importance in tumorigenesis. In this study we aim to establish the mutation spectrum and to understand the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26b15f67666ba69c58b1c6156f2261a
http://www.biomedcentral.com/1471-2407/6/93
http://www.biomedcentral.com/1471-2407/6/93
Publikováno v:
Yi chuan = Hereditas. 27(1)
To explore the status of heteroplasmy and homoplasmy of Mitochondrial DNA somatic mutations in different tumors. DNA from 149 tumors and corresponding normal tissues were extracted and entire mitochondrial genome was amplified using 32 pairs of overl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaf5dc6a0013b43c34675488f7624ca8
https://pubmed.ncbi.nlm.nih.gov/15730958
https://pubmed.ncbi.nlm.nih.gov/15730958