Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Duan Sun Zhang"'
Autor:
Déborah I. Scheffer, Duan-Sun Zhang, Jun Shen, Artur Indzhykulian, K. Domenica Karavitaki, Yichao Joy Xu, Qinchuan Wang, Jim Jung-Ching Lin, Zheng-Yi Chen, David P. Corey
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1811-1818 (2015)
Hair cells of the inner ear are mechanoreceptors for hearing and balance, and proteins highly enriched in hair cells may have specific roles in the development and maintenance of the mechanotransduction apparatus. We identified XIRP2/mXinβ as an enr
Externí odkaz:
https://doaj.org/article/0f3cc178c1dc4fdc9d7ed0a8f87b94ce
Autor:
Jim J.-C. Lin, David P. Corey, Zheng-Yi Chen, K. Domenica Karavitaki, Duan Sun Zhang, Jun Shen, Artur A. Indzhykulian, Qinchuan Wang, Deborah I. Scheffer, Yichao Joy Xu
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1811-1818 (2015)
SummaryHair cells of the inner ear are mechanoreceptors for hearing and balance, and proteins highly enriched in hair cells may have specific roles in the development and maintenance of the mechanotransduction apparatus. We identified XIRP2/mXinβ as
Autor:
David P. Corey, Melanie Barzik, Meghan C. Drummond, Claude Lechene, Thomas B. Friedman, Jonathan E. Bird, Duan-Sun Zhang, Lisa L. Cunningham
Publikováno v:
Nature Communications
The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every
Publikováno v:
AIP Conference Proceedings.
The study of mechanotransduction in cochlear hair cells requires stimulus methods that mimic the in-vivo stimulation. We have developed a new mechanical probe to better mimic the physiological stimulus delivered to cochlear hair cells through the ove
Autor:
Melissa A. Vollrath, Clifford J. Woolf, Kelvin Y. Kwan, Andrew Allchorne, David P. Corey, Duan-Sun Zhang, Adam Christensen
Publikováno v:
Neuron. 50(2):277-289
TRPA1, a member of the transient receptor potential (TRP) family of ion channels, is expressed by dorsal root ganglion neurons and by cells of the inner ear, where it has proposed roles in sensing sound, painful cold, and irritating chemicals. To tes
Myosin-VIIb, a Novel Unconventional Myosin, Is a Constituent of Microvilli in Transporting Epithelia
Autor:
David P. Corey, Brian J. Schwender, Bruce Derfler, Duan-Sun Zhang, Mark S. Mooseker, Zheng-Yi Chen, Tama Hasson
Publikováno v:
Genomics. 72:285-296
Mouse myosin-VIIb, a novel unconventional myosin, was cloned from the inner ear and kidney. The human myosin-VIIb (HGMW-approved symbol MYO7B) sequence and exon structure were then deduced from a human BAC clone. The mouse gene was mapped to chromoso
Autor:
William U. Shipley, David J. Kwiatkowski, David W. Yandell, Chi-Wei Lin, W. Scott McDougal, Duan-Sun Zhang
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 1:88-92
Allelic losses involving chromosome 9q occur in a significant percentage of bladder tumors. Experimental evidence suggests that a putative tumor suppressor gene located on this chromosome may play a role in the development of bladder cancer. The prec
Autor:
Agnieszka K. Rzadzinska, Benjamin J. Perrin, Duan Sun Zhang, J. Collin Poczatek, Claude Lechene, James M. Ervasti, David P. Corey, Valeria Piazza, Mei Wang, Haydn M. Prosser
Publikováno v:
Nature
Multi-isotope imaging mass spectrometry is used to quantify protein turnover in animal stereocilia, showing that rapid turnover occurs only in stereocilia tips. In the auditory system, the mechanosensory hair cells of the inner ear convert sound-indu
Publikováno v:
AIP Conference Proceedings; 2016, Vol. 1703, p030004-1-030004-4, 4p
Autor:
Zheng-Yi Chen, Duan Sun Zhang, Deborah I. Scheffer, Cyrille Sage, David P. Corey, Carolina Wedemeyer, Paola V. Plazas, Mingqian Huang, Veronique Pingault, A. Belén Elgoyhen
Publikováno v:
Journal of neurochemistry. 103(6)
Acetylcholine is a key neurotransmitter of the inner ear efferent system. In this study, we identify two novel nAChR subunits in the inner ear: α1 and γ, encoded by Chrna1 and Chrng, respectively. In situ hybridization shows that the messages of th