Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Duan Liu"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Purpose This study aimed to explore the prognostic factors and survival patterns based on the histological type for the perimenopausal endometrial carcinoma (PIPEC) patients treated with hysterectomy. Methods The PIPEC patients were selected
Externí odkaz:
https://doaj.org/article/926fbdd25eed4a8dbf3dc1f437e01a5e
Autor:
Huanyao Gao, Lixuan Wei, Shreya Indulkar, Thanh Thanh. L. Nguyen, Duan Liu, Ming-Fen Ho, Cheng Zhang, Hu Li, Richard M. Weinshilboum, James N. Ingle, Liewei Wang
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Endocrine therapy is the most important treatment modality of breast cancer patients whose tumors express the estrogen receptor α (ERα). The androgen receptor (AR) is also expressed in the vast majority (80–90%) of ERα-positi
Externí odkaz:
https://doaj.org/article/0906792d3b1b42248df6ef4f3c484ff2
Publikováno v:
Biomolecules & Biomedicine (2024)
The study aimed to identify the independent prognostic factors of mixed endometrial carcinoma (MEC) patients treated with hysterectomy and to explore the optimal treatment modalities for overall survival (OS) and cancer-specific survival (CSS). Using
Externí odkaz:
https://doaj.org/article/117a33812351470f8dfe44a089ef6396
Autor:
Thanh Thanh L. Nguyen, Duan Liu, Huanyao Gao, Zhenqing Ye, Jeong‐Heon Lee, Lixuan Wei, Jia Yu, Lingxin Zhang, Liewei Wang, Tamas Ordog, Richard M. Weinshilboum
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 11, Pp 2758-2771 (2022)
Abstract Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3′ ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes. However, the rol
Externí odkaz:
https://doaj.org/article/9e5c3f5bc7ca48ffa83f71f51b41317a
Autor:
Xiujuan Zhu, Huanyao Gao, Sisi Qin, Duan Liu, Junmei Cairns, Yayun Gu, Jia Yu, Richard M. Weinshilboum, Liewei Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The cytochromes P450 (CYPs) represent a large gene superfamily that plays an important role in the metabolism of both exogenous and endogenous compounds. We have reported that the testis-specific Y-encoded-like proteins (TSPYLs) are novel CYP gene tr
Externí odkaz:
https://doaj.org/article/a54ad5ce945b4d519179b4be751437da
Autor:
Jeremiah B. Joyce, Caroline W. Grant, Duan Liu, Siamak MahmoudianDehkordi, Rima Kaddurah-Daouk, Michelle Skime, Joanna Biernacka, Mark A. Frye, Taryn Mayes, Thomas Carmody, Paul E. Croarkin, Liewei Wang, Richard Weinshilboum, William V. Bobo, Madhukar H. Trivedi, Arjun P. Athreya
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Combination antidepressant pharmacotherapies are frequently used to treat major depressive disorder (MDD). However, there is no evidence that machine learning approaches combining multi-omics measures (e.g., genomics and plasma metabolomics)
Externí odkaz:
https://doaj.org/article/bf2ec854954a47dc9cf4c2ef7c12b746
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
We use the mobile phone camera as a new spectral imaging device to obtain raw responses of samples for spectral estimation and propose an improved sequential adaptive weighted spectral estimation method. First, we verify the linearity of the raw resp
Externí odkaz:
https://doaj.org/article/4bb35d2c152d457fa5a853e864ac1580
Autor:
Yongxian Zhuang, Jordan M. Grainger, Peter T. Vedell, Jia Yu, Ann M. Moyer, Huanyao Gao, Xiao-Yang Fan, Sisi Qin, Duan Liu, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Richard M. Weinshilboum, Liewei Wang
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract The application of patient-derived xenografts (PDX) in drug screening and testing is a costly and time-consuming endeavor. While cell lines permit extensive mechanistic studies, many human breast cancer cell lines lack patient characteristic
Externí odkaz:
https://doaj.org/article/d0faaa823e1d474ca427db78a9f24251
Autor:
Lingxin Zhang, Vivekananda Sarangi, Irene Moon, Jia Yu, Duan Liu, Sandhya Devarajan, Joel M. Reid, Krishna R. Kalari, Liewei Wang, Richard Weinshilboum
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 727-742 (2020)
Single nucleotide variants in the open reading frames (ORFs) of pharmacogenes are important causes of interindividual variability in drug response. The functional characterization of variants of unknown significance within ORFs remains a major challe
Externí odkaz:
https://doaj.org/article/1144fdfe27ac414da66d29418b5a2e86
Publikováno v:
Ecological Indicators, Vol 133, Iss , Pp 108385- (2021)
Developing sustainable agriculture in ecologically fragile areas is important. To date, the ecological service value of the rice-fish co-culture in the northwest area of the Hu Line is unclear. Based on the Millennium Ecosystem Assessment and underst
Externí odkaz:
https://doaj.org/article/60f5ecd7b59140378d097c654ba36d74