Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Duah Alkam"'
Autor:
Stephanie Biedka, Duah Alkam, Charity L. Washam, Svitlana Yablonska, Aaron Storey, Stephanie D. Byrum, Jonathan S. Minden
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Typical multiomics studies employ separate methods for DNA, RNA, and protein sample preparation, which is labor intensive, costly, and prone to sampling bias. We describe a method for preparing high-quality, sequencing-ready DNA and RNA, and
Externí odkaz:
https://doaj.org/article/583a1926d7ed464d861943f11ed1de87
Autor:
Samrat Roy Choudhury, Stephanie D. Byrum, Duah Alkam, Cody Ashby, Fenghuang Zhan, Alan J. Tackett, Frits Van Rhee
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Oncogenic overexpression of integrin-β7 (ITGB7) in cases of high-risk multiple myeloma (MM) was reported to promote enhanced interactions between neoplastic plasma-B cells and stromal cells to develop cell-adhesion mediated drug
Externí odkaz:
https://doaj.org/article/da8930f7c5b643a592478ee5b0d59690
Autor:
Yuguo Zhang, Musa Gabere, Mika A. Taylor, Camila C. Simoes, Chelsae Dumbauld, Oumar Barro, Mulu Z. Tesfay, Alicia L. Graham, Khandoker Usran Ferdous, Alena V. Savenka, Jean Christopher Chamcheu, Charity L. Washam, Duah Alkam, Allen Gies, Stephanie D. Byrum, Matteo Conti, Steven R. Post, Thomas Kelly, Mitesh J. Borad, Martin J. Cannon, Alexei Basnakian, Bolni M. Nagalo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
It has long been known that oncolytic viruses wield their therapeutic capability by priming an inflammatory state within the tumor and activating the tumor immune microenvironment, resulting in a multifaceted antitumor immune response. Vaccine-derive
Externí odkaz:
https://doaj.org/article/cc4969f03b474994ad64d25b34a6caa6
Autor:
Thidathip Wongsurawat, Piroon Jenjaroenpun, Annick De Loose, Duah Alkam, David W. Ussery, Intawat Nookaew, Yuet-Kin Leung, Shuk-Mei Ho, John D. Day, Analiz Rodriguez
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Molecular biomarkers provide both diagnostic and prognostic results for patients with diffuse glioma, the most common primary brain tumor in adults. Here, we used a long-read nanopore-based sequencing technique to simultaneously assess IDH m
Externí odkaz:
https://doaj.org/article/692d00e2e0df4aeeb11fc2273717298d
Autor:
Karen K. Ling, Michaela Jackson, Duah Alkam, Dawei Liu, Norm Allaire, Chao Sun, Mahmoud Kiaei, Alexander McCampbell, Frank Rigo
Publikováno v:
Neurobiology of Disease, Vol 114, Iss , Pp 174-183 (2018)
Amyotrophic lateral sclerosis (ALS) is a fatal adult onset motor neuron disease characterized by progressive denervation and subsequent motor impairment. EphA4, a negative regulator of axonal growth, was recently identified as a genetic modifier in f
Externí odkaz:
https://doaj.org/article/8b15b16f25a84738b84ecdc2cd0e3567
Autor:
Yuguo Zhang, Mulu Tesfay, Khandoker U. Ferdous, Mika Taylor, Musa Gabere, Camila C. Simoes, Chelsae Dumbauld, Oumar Barro, Alicia L. Graham, Charity L. Washam, Duah Alkam, Allen Gies, Jean Christopher Chamcheu, Stephanie D. Byrum, Steven R. Post, Thomas Kelly, Mitesh J. Borad, Martin J. Cannon, Alexei Basnakian, Bolni M. Nagalo
Oncolytic viruses can effectively unwrap a multimodal anti-tumor activity, encompassing a selective tumor cell killing and promoting a systemic anti-tumor immunity, making them a formidable foe against cancer. Among these, several members of the Rhab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb149e9504c232288bab921567f304f7
https://doi.org/10.1101/2022.09.09.507330
https://doi.org/10.1101/2022.09.09.507330
Autor:
Kanishka Manna, Prashanthi Dharanipragada, Duah Alkam, Nathan L. Avaritt, Charity L. Washam, Tung-chin Chiang, Michael S Robeson, Ricky D. Edmondson, Samuel G. Mackintosh, Zhentao Yang, Yan Wang, Shirley H. Lomeli, Gatien Moriceau, Roger S. Lo, Alan J. Tackett, Stephanie D. Byrum
Therapeutic approaches to treat melanoma include small molecule drugs that target activating protein mutations in pro-growth signaling pathways like the MAPK pathway. While beneficial to the approximately 50% of patients with activatingBRAFV600mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b31ecbe4a7f506bf06d484cfc388b48
https://doi.org/10.17504/protocols.io.b68erhte
https://doi.org/10.17504/protocols.io.b68erhte
Autor:
Piroon Jenjaroenpun, Analiz Rodriguez, Annick De Loose, Yuet-Kin Leung, Shuk-Mei Ho, Thidathip Wongsurawat, John D. Day, Duah Alkam, David W. Ussery, Intawat Nookaew
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Molecular biomarkers provide both diagnostic and prognostic results for patients with diffuse glioma, the most common primary brain tumor in adults. Here, we used a long-read nanopore-based sequencing technique to simultaneously assess IDH mutation s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1e1fd7062c442675d9b44d00eb6efc
http://link.springer.com/article/10.1186/s40478-020-00963-0
http://link.springer.com/article/10.1186/s40478-020-00963-0
Autor:
Kanishka Manna, Prashanthi Dharanipragada, Duah Alkam, Nathan L. Avaritt, Charity L. Washam, Michael S. Robeson, Ricky D. Edmondson, Samuel G. Mackintosh, Zhentao Yang, Yan Wang, Shirley H. Lomeli, Gatien Moriceau, Stephanie D. Byrum, Roger S. Lo, Alan J. Tackett
Therapeutic approaches to treat melanoma include small molecule drugs that target activating protein mutations in pro-growth signaling pathways like the MAPK pathway. While beneficial to the approximately 50% of patients with activating BRAFV600 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c901c8d9ebf37fbe61741e5a30391d
https://doi.org/10.1101/2022.02.15.480454
https://doi.org/10.1101/2022.02.15.480454
Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
Autor:
Allen Gies, Jordan T. Bird, Duah Alkam, Kevin Chappell, Stephanie D. Byrum, Sayem Miah, Kanishka Manna, Christopher E. Randolph, Matthew D. Thompson, Lindsey Hazeslip, Charity L. Washam, Maroof K. Zafar, Alicia K. Byrd, Stefan Graw
Publikováno v:
Mol Omics
Triple negative breast cancer (TNBC) is an aggressive type of breast cancer with very little treatment options. TNBC is very heterogeneous with large alterations in the genomic, transcriptomic, and proteomic landscapes leading to various subtypes wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec99fd69338590c103006daa8bf46bb7
https://europepmc.org/articles/PMC8504614/
https://europepmc.org/articles/PMC8504614/