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pro vyhledávání: '"Duaa Babaer"'
Publikováno v:
Oncology letters. 18(6)
Previous phase I DNA-vaccine based clinical trials using Mammaglobin-A (Mam-A), a human breast tumor associated antigen (TAA), demonstrated that this agent was safe and efficient at treating patients with stage IV breast cancer. The long-term success
Autor:
Elbert L. Myles, Roy Zent, Suneetha Amara, Duaa Babaer, Venkataswarup Tiriveedhi, Jeffrey C. Rathmell, Brenda S. McAdory, Owen Johnson
Publikováno v:
Cancers
Volume 11
Issue 5
Cancers, Vol 11, Iss 5, p 672 (2019)
Volume 11
Issue 5
Cancers, Vol 11, Iss 5, p 672 (2019)
Mammaglobin-A (MamA) is overexpressed in 40&ndash
80% of all human breast cancers. Recent phase I clinical trials of the MamA DNA vaccine showed encouraging safety outcomes. However, this vaccine elicited only a modest increase in MamA specific
80% of all human breast cancers. Recent phase I clinical trials of the MamA DNA vaccine showed encouraging safety outcomes. However, this vaccine elicited only a modest increase in MamA specific
Autor:
Duaa Babaer, Yan Zhao, Jens Titze, Philip E. Lammers, Suneetha Amara, Michael T. Ivy, Venkataswarup Tiriveedhi
Publikováno v:
Oncotarget
Recent evidence from our laboratory has demonstrated that high salt (Δ0.05 M NaCl) induced inflammatory response and cancer cell proliferation through salt inducible kinase-3 (SIK3) upregulation. As calcium influx is known to effect inflammatory res